Featured Research

from universities, journals, and other organizations

New Study Details Trends In Diagnosis, Treatment Of Brain Tumors

Date:
February 6, 2005
Source:
University Of Virginia Health System
Summary:
A two year study involving over 560 patients with the newly-diagnosed malignant brain tumors shows that patterns of care are varied and there is a need for new, detailed clinical guidelines for management of brain tumors.

CHARLOTTESVILLE, Va. (Feb. 2, 2005) -- A two year study involving over 560 patients with the newly-diagnosed malignant brain tumors shows that patterns of care are varied and there is a need for new, detailed clinical guidelines for management of brain tumors. The study is published in the Feb. 2, 2005 issue of the Journal of the American Medical Association (JAMA).

“We have a long way to go because we still do not have a reliable way of controlling these malignant tumors,” said study co-author Dr. Edward R. Laws, Jr., professor of neurological surgery, internal medicine and pediatrics at the University of Virginia Health System. “Physicians and other caregivers do fairly well treating these tumors, but this important study helps us see where we might do better.” The average life expectancy for patients with malignant brain tumors is a little over one year, unchanged since the 1960’s, Laws said.

The study found that there are common practice patterns that follow published medical findings, such as the use of radiation therapy, magnetic resonance imaging (MRI) or surgery on brain tumor patients. Over 75 percent of patients underwent such procedures (92 percent in the case of MRI, 87 percent in the case of postoperative radiation therapy).

But, the study discovered that some practice patterns contradict published guidelines. Over 80 percent of the patients received anti-epileptic drugs, where there is little value for patients who do not have epileptic seizures and significant side effects. The infrequent use of chemotherapy may also conflict with published literature. Only 54 percent of patients received chemotherapy, which has been found to correlate with increased survival, though modest.

One of the most surprising findings was the infrequent use of anti-depressant medications (8 percent) for patients with symptoms of depression. “The incidence of depression is very high and very few of these patients are treated for depression. This isone patient management tool that could be implement immediately to help a patients’ quality of life,” Laws said. Few patients (7 percent) received the drug heparin for blood clots as well, despite the risk of deep venous thrombosis. The study found conflicting literature on the efficacy of low-dose heparin in brain tumor patients.

The JAMA article was the final report on the “Glioma Outcomes Project,” a prospective, longitudinal database begun in 1997 that tracked clinical practice patterns and outcomes among North American patients with malignant gliomas at 52 clinical sites, including U. Va.

“Now we have a really solid benchmark,” Laws said. “This paper tells us a great deal about where we are now and where we need to go in diagnosing and treating malignant brain tumors. When we have studies involving the same kind of patient treated with new ways, we can hopefully answer the questions- is it really better than the treatment standard in 2003 or 2004?”


Story Source:

The above story is based on materials provided by University Of Virginia Health System. Note: Materials may be edited for content and length.


Cite This Page:

University Of Virginia Health System. "New Study Details Trends In Diagnosis, Treatment Of Brain Tumors." ScienceDaily. ScienceDaily, 6 February 2005. <www.sciencedaily.com/releases/2005/02/050204215353.htm>.
University Of Virginia Health System. (2005, February 6). New Study Details Trends In Diagnosis, Treatment Of Brain Tumors. ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/2005/02/050204215353.htm
University Of Virginia Health System. "New Study Details Trends In Diagnosis, Treatment Of Brain Tumors." ScienceDaily. www.sciencedaily.com/releases/2005/02/050204215353.htm (accessed August 30, 2014).

Share This




More Health & Medicine News

Saturday, August 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com
Liberia Continues Fight Against Ebola

Liberia Continues Fight Against Ebola

AFP (Aug. 30, 2014) Authorities in Liberia try to stem the spread of the Ebola epidemic by raising awareness and setting up sanitation units for people to wash their hands. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

Reuters - US Online Video (Aug. 30, 2014) California lawmakers pass a bill requiring universities to adopt "affirmative consent" language in their definitions of consensual sex, part of a nationwide drive to curb sexual assault on campuses. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins