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Intermittent Prophylaxis Prevents Malaria In Infants

Date:
October 3, 2005
Source:
BMJ-British Medical Journal
Summary:
Giving infants preventive treatment for malaria can reduce malaria and anaemia even in seasonal, high transmission areas such as Ghana, finds a study in this week's BMJ.

Giving infants preventive treatment for malaria can reduce malaria andanaemia even in seasonal, high transmission areas such as Ghana, findsa study in this week's BMJ.

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But concern exists about a possible rebound when treatment is stopped, warn the authors.

The study followed over 2,400 infants in Ghana who were given apreventive treatment for malaria or a placebo (dummy pill) when theyreceived routine vaccinations and at 12 months of age.

Preventive treatment reduced malaria by 25% and anaemia by 35%up to age 15 months. However, malaria levels increased 20% whentreatment was stopped in the second year of life.

The protective effect was also substantially lower than that reported from previous studies in Tanzania.

Because these findings run counter to earlier studies, theauthors suggest that more data are needed to decide on the appropriatedose schedule for preventive drugs in areas with high seasonaltransmission and its interaction with insecticide treated bed nets.

However, intermittent preventive treatment in infants, linkedto the expanded programme of immunisation schedule, has the potentialto reduce the burden of malaria even in areas with high seasonaltransmission, they conclude.


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Cite This Page:

BMJ-British Medical Journal. "Intermittent Prophylaxis Prevents Malaria In Infants." ScienceDaily. ScienceDaily, 3 October 2005. <www.sciencedaily.com/releases/2005/10/051003080039.htm>.
BMJ-British Medical Journal. (2005, October 3). Intermittent Prophylaxis Prevents Malaria In Infants. ScienceDaily. Retrieved March 28, 2015 from www.sciencedaily.com/releases/2005/10/051003080039.htm
BMJ-British Medical Journal. "Intermittent Prophylaxis Prevents Malaria In Infants." ScienceDaily. www.sciencedaily.com/releases/2005/10/051003080039.htm (accessed March 28, 2015).

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