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Intermittent Prophylaxis Prevents Malaria In Infants

Date:
October 3, 2005
Source:
BMJ-British Medical Journal
Summary:
Giving infants preventive treatment for malaria can reduce malaria and anaemia even in seasonal, high transmission areas such as Ghana, finds a study in this week's BMJ.

Giving infants preventive treatment for malaria can reduce malaria and anaemia even in seasonal, high transmission areas such as Ghana, finds a study in this week's BMJ.

But concern exists about a possible rebound when treatment is stopped, warn the authors.

The study followed over 2,400 infants in Ghana who were given a preventive treatment for malaria or a placebo (dummy pill) when they received routine vaccinations and at 12 months of age.

Preventive treatment reduced malaria by 25% and anaemia by 35% up to age 15 months. However, malaria levels increased 20% when treatment was stopped in the second year of life.

The protective effect was also substantially lower than that reported from previous studies in Tanzania.

Because these findings run counter to earlier studies, the authors suggest that more data are needed to decide on the appropriate dose schedule for preventive drugs in areas with high seasonal transmission and its interaction with insecticide treated bed nets.

However, intermittent preventive treatment in infants, linked to the expanded programme of immunisation schedule, has the potential to reduce the burden of malaria even in areas with high seasonal transmission, they conclude.


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Cite This Page:

BMJ-British Medical Journal. "Intermittent Prophylaxis Prevents Malaria In Infants." ScienceDaily. ScienceDaily, 3 October 2005. <www.sciencedaily.com/releases/2005/10/051003080039.htm>.
BMJ-British Medical Journal. (2005, October 3). Intermittent Prophylaxis Prevents Malaria In Infants. ScienceDaily. Retrieved April 16, 2014 from www.sciencedaily.com/releases/2005/10/051003080039.htm
BMJ-British Medical Journal. "Intermittent Prophylaxis Prevents Malaria In Infants." ScienceDaily. www.sciencedaily.com/releases/2005/10/051003080039.htm (accessed April 16, 2014).

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