Young teens who smoked just one cigarette at the age of 11 were twice as likely to take up smoking within the next few years as their peers who resisted the urge, the study shows. This was despite not having smoked in the intervening period.

In 2004, 14% of 11 year olds and 62% of 15 year olds in England said they had experimented with cigarettes.

The researchers base their findings on annual surveys of almost 6000 eleven to 16 year olds attending 36 representative schools across South London, and measurements of salivary cotinine, a biochemical indicator of nicotine intake.

Full information for each of the five years was available for just over a third of the entire sample.

By the age of 14, pupils who had given smoking a go just once at the age of 11 were twice as likely to have become regular smokers as their peers who had not tried out smoking. This was the case even after a gap of three years or more.

These findings held true irrespective of gender, ethnicity, and deprivation, all factors known to influence the likelihood of taking up smoking.

Other influential factors, such as whether the parents smoked. or whether the pupil was a bit of a rebel, also had no bearing on the results.

The researchers say that their findings provide the first clear evidence of a "sleeper effect" or period of "dormant vulnerability," for teenagers who experiment with smoking just the once.

Just one cigarette could change the reward pathway in the brain, which might then be activated by triggers, such as stress, depression, or the school environment, suggest the authors.

Alternatively, trying out a cigarette might simply break down the social barriers that prevent teens from smoking, such as fear of displeasing adults or insecurities around how to smoke, they say.

Note: If no author is given, the source is cited instead.

• Smoking
• Teen Health
• Staying Healthy

• Smoking Addiction
• Behavior
• Addiction

• Nicotine
• Tobacco smoking
• Bronchitis
• Lung cancer
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