Featured Research

from universities, journals, and other organizations

Study Links Allergies To Parkinson's Disease

Date:
August 8, 2006
Source:
Mayo Clinic
Summary:
Researchers from Mayo Clinic have discovered that allergic rhinitis is associated with the development of Parkinson's disease later in life.

Researchers from Mayo Clinic have discovered that allergic rhinitis is associated with the development of Parkinson's disease later in life. Findings will be published in the Aug. 8 issue of the journal Neurology.

Related Articles


"The association with Parkinson's disease is increased to almost three times that of someone who does not have allergic rhinitis," says James Bower, M.D., Mayo Clinic neurologist and lead study investigator. "That's actually a pretty high elevation."

Previous studies had shown that people who regularly take nonsteroidal anti-inflammatory drugs, such as ibuprofen, are less likely to develop Parkinson's disease. These results prompted the Mayo Clinic investigators to look further into the links between diseases characterized by inflammation and Parkinson's. They studied 196 people who developed Parkinson's disease, matched with people of similar age and gender who did not develop Parkinson's. The study was conducted in Olmsted County, Minn., home of Mayo Clinic, over a 20-year period.

The researchers examined these groups to determine if those who developed Parkinson's disease had more inflammatory diseases. They found that those with allergic rhinitis were 2.9 times more likely to develop Parkinson's. They did not find a similar association between inflammatory diseases such as lupus, rheumatoid arthritis, pernicious anemia or vitiligo and Parkinson's disease. The researchers hypothesize that they may not have found significant links between these diseases and Parkinson's disease due to the relatively small number of those in the population who have these diseases, and thus the small number with these diseases in their population sample study. They also did not find the same association with Parkinson's disease in patients with asthma that they discovered in those with allergic rhinitis.

Dr. Bower says that this study did not examine patients' types of allergies or when they developed allergies.

The investigators theorize that a tendency toward inflammation is the key link between the diseases.

"People with allergic rhinitis mount an immune response with their allergies, so they may be more likely to mount an immune response in the brain as well, which would produce inflammation," Dr. Bower says. "The inflammation produced may release certain chemicals in the brain and inadvertently kill brain cells, as we see in Parkinson's."

Dr. Bower explains that this study does not prove that allergies cause Parkinson's disease; instead, it points to an association between the two diseases. He advises that allergy patients can do little to reduce the potential risk for Parkinson's.

"I wouldn't worry if you have allergies," he says. "Treat the allergy symptoms you have to alleviate them at the time. At this point, we have no good evidence that this treatment will protect you from possibly developing Parkinson's disease later."

Dr. Bower and colleagues hope, however, that the clues in this study may give scientists a strong hint about inflammation's role in Parkinson's.

"This is exciting, because we may be able to develop medications to block the inflammation," he says.

Parkinson's is a complex disease, says Dr. Bower, because many factors can contribute to its development and its causes can differ. The complexity can be compared to heart attacks, which can be caused by hypertension, high cholesterol or smoking, among other factors. Thus, allergic rhinitis would now be considered one among many possible risk factors for development of Parkinson's disease.

Parkinson's disease affects nerve cells (neurons) in the part of the brain that controls muscle movement. People with Parkinson's disease often experience trembling, muscle rigidity, difficulty walking, and problems with balance and coordination. These symptoms generally develop after age 50, although the disease also affects a small percentage of younger people. The normal lifetime risk to develop Parkinson's disease for men and women combined is 1.7 percent.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Cite This Page:

Mayo Clinic. "Study Links Allergies To Parkinson's Disease." ScienceDaily. ScienceDaily, 8 August 2006. <www.sciencedaily.com/releases/2006/08/060808091749.htm>.
Mayo Clinic. (2006, August 8). Study Links Allergies To Parkinson's Disease. ScienceDaily. Retrieved March 29, 2015 from www.sciencedaily.com/releases/2006/08/060808091749.htm
Mayo Clinic. "Study Links Allergies To Parkinson's Disease." ScienceDaily. www.sciencedaily.com/releases/2006/08/060808091749.htm (accessed March 29, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, March 29, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) — Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) — The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com
House Ready to Pass Medicare Doc Bill

House Ready to Pass Medicare Doc Bill

AP (Mar. 26, 2015) — In rare bipartisan harmony, congressional leaders pushed a $214 billion bill permanently blocking physician Medicare cuts toward House passage Thursday, moving lawmakers closer to resolving a problem that has plagued them for years. (March 26) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins