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Over-the-counter Eardrops May Cause Hearing Loss Or Damage, Study Suggests

Date:
January 30, 2008
Source:
McGill University Health Centre
Summary:
A new study has revealed that certain over-the-counter earwax softeners containing the active ingredient triethanolamine polypeptide oleate condensate (10%) can cause severe inflammation and damage to the eardrum and inner ear. "Because some of these products are readily available to the public without a consultation with or prescription from a physician, it is important to make sure they are safe to use. Our study shows that in a well-established animal model, one such product, Cerumenex, is in fact, toxic to the cells of the ear," says Dr. Daniel of The Montreal Children's Hospital.

A new study, led by researchers at The Montreal Children's Hospital (MCH) of the MUHC, has revealed that certain over-the-counter earwax softeners can cause severe inflammation and damage to the eardrum and inner ear. The results of the study, recently published in The Laryngoscope, suggest that use of these medications should be discouraged.

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"Patients often complain that wax is blocking their ears and is causing discomfort and sometimes deafness," says Dr. Sam Daniel principal investigator of the study and director of McGill Auditory Sciences Laboratory at The Children's. "Over-the-counter earwax softeners are used to breakup and disperse this excess wax. However, the effects of these medications on the cells of the ear had not been thoroughly analyzed."

"Because some of these products are readily available to the public without a consultation with or prescription from a physician, it is important to make sure they are safe to use. Our study shows that in a well-established animal model, one such product, Cerumenex, is in fact, toxic to the cells of the ear," says Dr. Daniel.

Dr. Daniel and his team studied the impact of Cerumenex on hearing. In addition, overall toxicity in the outer ear and changes in the nerve cells of the inner ear were analyzed.

"Harmful effects to many of the cells were observed after only one dose," says Dr. Melvin Schloss co-author and MCH Director of Otolaryngology. "We observed reduced hearing, severe inflammation, and lesions to the nerve cells."

"We believe these findings are applicable to humans," add Dr. Daniel. "The animal model we chose has been widely used to test toxicity. In addition, this model has a very similar hearing mechanism. Overall, our findings suggest that Cerumenex has a toxic potential and it should be used with caution."


Story Source:

The above story is based on materials provided by McGill University Health Centre. Note: Materials may be edited for content and length.


Cite This Page:

McGill University Health Centre. "Over-the-counter Eardrops May Cause Hearing Loss Or Damage, Study Suggests." ScienceDaily. ScienceDaily, 30 January 2008. <www.sciencedaily.com/releases/2008/01/080128113212.htm>.
McGill University Health Centre. (2008, January 30). Over-the-counter Eardrops May Cause Hearing Loss Or Damage, Study Suggests. ScienceDaily. Retrieved February 27, 2015 from www.sciencedaily.com/releases/2008/01/080128113212.htm
McGill University Health Centre. "Over-the-counter Eardrops May Cause Hearing Loss Or Damage, Study Suggests." ScienceDaily. www.sciencedaily.com/releases/2008/01/080128113212.htm (accessed February 27, 2015).

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