Featured Research

from universities, journals, and other organizations

Model Identifies Targets For Eradication Of Malaria

Date:
March 16, 2008
Source:
Public Library of Science
Summary:
Scientists have shown that malaria eradication in Africa is sustainable, and any re-emergence of malaria in industrialized nations is highly unlikely. Researchers have created a mathematical model of malaria transmission throughout sub-Saharan Africa.

Scientists at the Instituto Gulbenkian de Ciκncia (IGC), in Portugal, have shown that Malaria eradication in Africa is sustainable, and any re-emergence of malaria in industrialized nations is highly unlikely. Working with colleagues in Kenya, the IGC researchers created a mathematical model of malaria transmission throughout sub-Saharan Africa.

Related Articles


After several exposures to malaria, humans develop clinical immunity to the disease. In this state, they no longer have symptoms of malaria, but are nevertheless capable of transmitting the disease to others. In regions where malaria is endemic, many people have developed clinical immunity, and this has a large effect on how the disease spreads, that is, on its epidemiology.

Gabriela Gomes and her team at the Theoretical Epidemiology group developed a mathematical model which, for the first time, estimates the significance of asymptomatic infections in malaria transmission when looking at the distribution of the disease in different populations. They applied their model to data from hospital admissions of children with malaria, provided by researchers working in eight different regions in sub-Saharan Africa, where malaria is endemic.

The model shows that, contrary to what was previously thought, in regions of moderate transmission there is a threshold for malaria eradication, separating endemic and malaria-free states. Any intervention success depends critically on reducing occurrence of disease below this threshold, which the model predicts to be possible in areas of moderate transmission, which is the case for most of Africa.

Industrialised nations sit well below this threshold, in the malaria-free state, since the number of clinically immune people is extremely low, making any re-emergence of malaria in these countries highly improbable.

Ricardo Αguas, first author of the paper, says, "This is a very powerful model, since it should allow us to determine quantifiable targets for reducing transmission of malaria (by providing mosquito nets, for example) and for fighting the disease (through mass- handing out of anti-malaria drugs), for a specific region."

Gabriela Gomes added, "Huge efforts are being put into fighting malaria in developing countries. Our model presents a very optimistic outlook for eradicating the disease in areas where it is moderately endemic, contrary to current thinking. We are now looking for research partners who may provide us with more clinical data, from more regions in Africa, which we could use to strengthen our model, and feed into effective eradication programmes."

Citation: Αguas R, White LJ, Snow RW, Gomes MGM (2008) Prospects for Malaria Eradication in Sub-Saharan Africa. PLoS One 3(3): e1767. doi:10.1371/journal.pone.0001767 http://www.plosone.org/doi/pone.0001767


Story Source:

The above story is based on materials provided by Public Library of Science. Note: Materials may be edited for content and length.


Cite This Page:

Public Library of Science. "Model Identifies Targets For Eradication Of Malaria." ScienceDaily. ScienceDaily, 16 March 2008. <www.sciencedaily.com/releases/2008/03/080311215658.htm>.
Public Library of Science. (2008, March 16). Model Identifies Targets For Eradication Of Malaria. ScienceDaily. Retrieved November 21, 2014 from www.sciencedaily.com/releases/2008/03/080311215658.htm
Public Library of Science. "Model Identifies Targets For Eradication Of Malaria." ScienceDaily. www.sciencedaily.com/releases/2008/03/080311215658.htm (accessed November 21, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) — Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) — Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com
Milestone Birthdays Can Bring Existential Crisis, Study Says

Milestone Birthdays Can Bring Existential Crisis, Study Says

Newsy (Nov. 21, 2014) — Researchers find that as people approach new decades in their lives they make bigger life decisions. Video provided by Newsy
Powered by NewsLook.com
Ebola: Life Without School in Guinea

Ebola: Life Without School in Guinea

AFP (Nov. 21, 2014) — Following the closure of schools and universities in Guinea because of the Ebola virus, students look for temporary work or gather in makeshift classrooms to catch up on their syllabus. Duration: 02:14 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins