Featured Research

from universities, journals, and other organizations

Race, Family History Or Baseline PSA: Which Best Predicts Prostate Cancer Risk?

Date:
May 15, 2008
Source:
American Urological Association
Summary:
African-American men with family histories of prostate cancer could benefit from a baseline prostate-specific antigen (PSA) reading to determine their probability of developing the disease.

African-American men with family histories of prostate cancer could benefit from a baseline prostate-specific antigen (PSA) reading to determine their probability of developing the disease. Researchers from Northwestern University in Chicago say this new perspective on testing could lead to highly individualized screening protocols based on a man’s baseline level and how it relates to established age-specific medians.

According to new data presented recently during the Annual Scientific Meeting of the American Urological Association (AUA) in Orlando, African-American men with known prostate cancer risk factors with baseline levels higher than the age-specific median are more likely to develop the disease in their lifetimes than the general population. However, African-American men with a family history were unlikely to develop prostate cancer if their baseline PSA level was below the age-specific median.

The effect of the baseline PSA level on future prostate cancer risk was so robust that the correlation held true even for men with other significant risk factors.

Using a study cohort drawn from a longitudinal screening study enrolling more than 26,000 volunteers between 1991 and 2001, researchers analyzed a group of 329 African-American men with a family history of prostate cancer. The volunteers were divided into three groups by ages: 40s, 50s and 60+ with a mean follow-up time of 19.5, 71 and 81 months, respectively. None of the men in their 40s or 50s with both risk factors and a baseline PSA below the median were diagnosed with prostate cancer.

Eight percent of men in their 40s with both risk factors and a PSA above the median were diagnosed, as were 16 percent of men in their 50s. Twice as many men in their 60s with both risk factors and a baseline PSA above the median were diagnosed with prostate cancer.


Story Source:

The above story is based on materials provided by American Urological Association. Note: Materials may be edited for content and length.


Journal Reference:

  1. Mondo DM, Roehl KA, Loeb S, Gashti SN, Griffin CR, Smith ND et al: Which is the most important risk factor for prostate cancer: race, family history, or baseline PSA level? J Urol, suppl., 2008; 179: 148, abstract 417. [link]

Cite This Page:

American Urological Association. "Race, Family History Or Baseline PSA: Which Best Predicts Prostate Cancer Risk?." ScienceDaily. ScienceDaily, 15 May 2008. <www.sciencedaily.com/releases/2008/05/080515072912.htm>.
American Urological Association. (2008, May 15). Race, Family History Or Baseline PSA: Which Best Predicts Prostate Cancer Risk?. ScienceDaily. Retrieved October 20, 2014 from www.sciencedaily.com/releases/2008/05/080515072912.htm
American Urological Association. "Race, Family History Or Baseline PSA: Which Best Predicts Prostate Cancer Risk?." ScienceDaily. www.sciencedaily.com/releases/2008/05/080515072912.htm (accessed October 20, 2014).

Share This



More Health & Medicine News

Monday, October 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Microneedle Patch Promises Painless Pricks

Microneedle Patch Promises Painless Pricks

Reuters - Innovations Video Online (Oct. 18, 2014) Researchers at The National University of Singapore have invented a new microneedle patch that could offer a faster and less painful delivery of drugs such as insulin and painkillers. Video provided by Reuters
Powered by NewsLook.com
Raw: Nurse Nina Pham Arrives in Maryland

Raw: Nurse Nina Pham Arrives in Maryland

AP (Oct. 17, 2014) The first nurse to be diagnosed with Ebola at a Dallas hospital walked down the stairs of an executive jet into an ambulance at an airport in Frederick, Maryland, on Thursday. Pham will be treated at the National Institutes of Health. (Oct. 16) Video provided by AP
Powered by NewsLook.com
Raw: Cruise Ship Returns to US Over Ebola Fears

Raw: Cruise Ship Returns to US Over Ebola Fears

AP (Oct. 17, 2014) A Caribbean cruise ship carrying a Dallas health care worker who is being monitored for signs of the Ebola virus is heading back to Texas, US, after being refused permission to dock in Cozumel, Mexico. (Oct. 17) Video provided by AP
Powered by NewsLook.com
Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

Spanish Govt: Four Suspected Ebola Cases in Spain Test Negative

AFP (Oct. 17, 2014) All four suspected Ebola cases admitted to hospitals in Spain on Thursday have tested negative for the deadly virus in a first round of tests, the government said Friday. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins