Featured Research

from universities, journals, and other organizations

First Optical Pacemaker: Laser Controls Beating Of Heart Muscle Cells In Cell Culture

Date:
May 29, 2008
Source:
Optical Society of America
Summary:
The world's first optical pacemaker has been devised. Powerful, but very short, laser pulses can help control the beating of heart muscle cells.

The world's first optical pacemaker has been devised. A team of scientists at Osaka University in Japan show that powerful, but very short, laser pulses can help control the beating of heart muscle cells.

"If you put a large amount of laser power through these cells over a very short time period, you get a huge response," says Nicholas Smith, who led the research. The laser pulses cause the release of calcium ions within the cells, Smith explains, and this action forces the cells to contract.

This technique provides a tool for controlling heart muscle cells in the laboratory, a breakthrough that may help scientists better understand the mechanism of heart muscle contraction.

One potential application of this technology is in studying uncoordinated contractions in heart muscle. Normally, heart muscle contracts in a highly coordinated fashion, and this is what allows the heart to pump blood through the vasculature. But in some people, this coordinated beating breaks down, and the heart twitches irregularly--a condition known as fibrillation.

The new laser technique may allow scientists to create a form of fibrillation in the test tube. The lasers can destabilize the beating of the cells in laboratory experiments by introducing a beat frequency in one target cell distinct from the surrounding cells. This would allow scientists to study irregular heart beats on a cellular level and screen anti-fibrillation drugs.

Outside the laboratory, exposing heart muscle cells to powerful laser pulses can have its drawbacks. Although the laser pulses last for less than a trillionth of a second, damaging effects can build up over time and this currently limits the possibility of clinical applications.

This work was supported by the Japan Science and Technology organization.


Story Source:

The above story is based on materials provided by Optical Society of America. Note: Materials may be edited for content and length.


Journal Reference:

  1. N.I. Smith et al. A Femtosecond Laser Pacemaker for Heart Muscle Cells. Optics Express, 2008

Cite This Page:

Optical Society of America. "First Optical Pacemaker: Laser Controls Beating Of Heart Muscle Cells In Cell Culture." ScienceDaily. ScienceDaily, 29 May 2008. <www.sciencedaily.com/releases/2008/05/080528095727.htm>.
Optical Society of America. (2008, May 29). First Optical Pacemaker: Laser Controls Beating Of Heart Muscle Cells In Cell Culture. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2008/05/080528095727.htm
Optical Society of America. "First Optical Pacemaker: Laser Controls Beating Of Heart Muscle Cells In Cell Culture." ScienceDaily. www.sciencedaily.com/releases/2008/05/080528095727.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Nigeria Beat Its Ebola Outbreak

How Nigeria Beat Its Ebola Outbreak

Newsy (Oct. 20, 2014) The World Health Organization has declared Nigeria free of Ebola. Health experts credit a bit of luck and the government's initial response. Video provided by Newsy
Powered by NewsLook.com
Another Study Suggests Viagra Is Good For The Heart

Another Study Suggests Viagra Is Good For The Heart

Newsy (Oct. 20, 2014) An ingredient in erectile-dysfunction medications such as Viagra could improve heart function. Perhaps not surprising, given Viagra's history. Video provided by Newsy
Powered by NewsLook.com
Ebola Worries End for Dozens on U.S. Watch Lists

Ebola Worries End for Dozens on U.S. Watch Lists

Reuters - US Online Video (Oct. 20, 2014) Forty-three people who had contact with Thomas Eric Duncan, the first person diagnosed with Ebola in the U.S., were cleared overnight of twice-daily monitoring after 21 days of showing no symptoms. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com
CDC Calls for New Ebola Safety Guidelines

CDC Calls for New Ebola Safety Guidelines

AP (Oct. 20, 2014) Centers for Disease Control and Prevention Director Dr. Tom Frieden laid out new guidelines for health care workers when dealing with the deadly Ebola virus including new precautions when taking off personal protective equipment. (Oct. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins