Featured Research

from universities, journals, and other organizations

Chemotherapy Diminishes Fertility In Breast Cancer Patients, Study Suggests

Date:
June 2, 2008
Source:
Dana-Farber Cancer Institute
Summary:
Pre-menopausal breast cancer survivors who were treated with chemotherapy following surgery were more likely to have diminished ovarian reserve -- the capacity of the ovaries to provide eggs capable of being fertilized -- compared to women who have never had breast cancer, according to a study led by Dana-Farber Cancer Institute investigators. Their findings will be presented at the annual meeting of the American Society of Clinical Oncology

Pre-menopausal breast cancer survivors who were treated with chemotherapy following surgery were more likely to have diminished ovarian reserve -- the capacity of the ovaries to provide eggs capable of being fertilized - compared to women who have never had breast cancer, according to a study led by Dana-Farber Cancer Institute investigators.

Their findings will be presented at the annual meeting of the American Society of Clinical Oncology (ASCO), May 30-June 3, in Chicago.

The researchers analyzed markers of ovarian reserve in 20 premenopausal breast cancer patients who had been treated with adjuvant chemotherapy, who were one or more years out from their diagnosis, and who had no evidence of recurrence. This group was compared with a "control" group of 20 like-aged women without a history of the disease.

The evaluation involved five tests conducted two, three or four days after a menstrual cycle to assess the ovaries' physical condition, hormone levels and a compound involved in the menstrual cycle. In four of the five tests, the breast cancer survivors had a worse ovarian reserve than did the control group. The other test showed no major difference between the two groups.

"These findings may have important implications for women who are interested in having children after receiving chemotherapy," said Ann Partridge, MD, MPH, of Dana-Farber, who led the study. "Studies that track breast cancer survivors following treatment are needed to determine the predictive value of these tests for pregnancy."

The study's co-authors are Kathryn Ruddy, MD, Shari Gelber, Eric Winer, MD, and Meghan Meyer of Dana-Farber, Boston; Lidia Schapira, MD, of Massachusetts General Hospital, Boston; and Elizabeth Ginsburg, MD, senior author, and Mary Abusief, MD, of Brigham and Women's Hospital, Boston.

Financial support for the study was provided by the Lance Armstrong Foundation.


Story Source:

The above story is based on materials provided by Dana-Farber Cancer Institute. Note: Materials may be edited for content and length.


Cite This Page:

Dana-Farber Cancer Institute. "Chemotherapy Diminishes Fertility In Breast Cancer Patients, Study Suggests." ScienceDaily. ScienceDaily, 2 June 2008. <www.sciencedaily.com/releases/2008/05/080530095450.htm>.
Dana-Farber Cancer Institute. (2008, June 2). Chemotherapy Diminishes Fertility In Breast Cancer Patients, Study Suggests. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2008/05/080530095450.htm
Dana-Farber Cancer Institute. "Chemotherapy Diminishes Fertility In Breast Cancer Patients, Study Suggests." ScienceDaily. www.sciencedaily.com/releases/2008/05/080530095450.htm (accessed July 25, 2014).

Share This




More Health & Medicine News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
Too Few Teens Receiving HPV Vaccination, CDC Says

Too Few Teens Receiving HPV Vaccination, CDC Says

Newsy (July 24, 2014) The Centers for Disease Control and Prevention is blaming doctors for the low number of children being vaccinated for HPV. Video provided by Newsy
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Doctor At Forefront Of Fighting Ebola Outbreak Gets Ebola

Newsy (July 24, 2014) Sheik Umar Khan has treated many of the people infected in the Ebola outbreak, and now he's become one of them. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

    Health News

      Environment News

        Technology News



          Save/Print:
          Share:

          Free Subscriptions


          Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

          Get Social & Mobile


          Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

          Have Feedback?


          Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
          Mobile: iPhone Android Web
          Follow: Facebook Twitter Google+
          Subscribe: RSS Feeds Email Newsletters
          Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins