Featured Research

from universities, journals, and other organizations

Chemotherapy Diminishes Fertility In Breast Cancer Patients, Study Suggests

Date:
June 2, 2008
Source:
Dana-Farber Cancer Institute
Summary:
Pre-menopausal breast cancer survivors who were treated with chemotherapy following surgery were more likely to have diminished ovarian reserve -- the capacity of the ovaries to provide eggs capable of being fertilized -- compared to women who have never had breast cancer, according to a study led by Dana-Farber Cancer Institute investigators. Their findings will be presented at the annual meeting of the American Society of Clinical Oncology

Pre-menopausal breast cancer survivors who were treated with chemotherapy following surgery were more likely to have diminished ovarian reserve -- the capacity of the ovaries to provide eggs capable of being fertilized - compared to women who have never had breast cancer, according to a study led by Dana-Farber Cancer Institute investigators.

Their findings will be presented at the annual meeting of the American Society of Clinical Oncology (ASCO), May 30-June 3, in Chicago.

The researchers analyzed markers of ovarian reserve in 20 premenopausal breast cancer patients who had been treated with adjuvant chemotherapy, who were one or more years out from their diagnosis, and who had no evidence of recurrence. This group was compared with a "control" group of 20 like-aged women without a history of the disease.

The evaluation involved five tests conducted two, three or four days after a menstrual cycle to assess the ovaries' physical condition, hormone levels and a compound involved in the menstrual cycle. In four of the five tests, the breast cancer survivors had a worse ovarian reserve than did the control group. The other test showed no major difference between the two groups.

"These findings may have important implications for women who are interested in having children after receiving chemotherapy," said Ann Partridge, MD, MPH, of Dana-Farber, who led the study. "Studies that track breast cancer survivors following treatment are needed to determine the predictive value of these tests for pregnancy."

The study's co-authors are Kathryn Ruddy, MD, Shari Gelber, Eric Winer, MD, and Meghan Meyer of Dana-Farber, Boston; Lidia Schapira, MD, of Massachusetts General Hospital, Boston; and Elizabeth Ginsburg, MD, senior author, and Mary Abusief, MD, of Brigham and Women's Hospital, Boston.

Financial support for the study was provided by the Lance Armstrong Foundation.


Story Source:

The above story is based on materials provided by Dana-Farber Cancer Institute. Note: Materials may be edited for content and length.


Cite This Page:

Dana-Farber Cancer Institute. "Chemotherapy Diminishes Fertility In Breast Cancer Patients, Study Suggests." ScienceDaily. ScienceDaily, 2 June 2008. <www.sciencedaily.com/releases/2008/05/080530095450.htm>.
Dana-Farber Cancer Institute. (2008, June 2). Chemotherapy Diminishes Fertility In Breast Cancer Patients, Study Suggests. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2008/05/080530095450.htm
Dana-Farber Cancer Institute. "Chemotherapy Diminishes Fertility In Breast Cancer Patients, Study Suggests." ScienceDaily. www.sciencedaily.com/releases/2008/05/080530095450.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Obesity Rates Steady Even As Americans' Waistlines Expand

Obesity Rates Steady Even As Americans' Waistlines Expand

Newsy (Sep. 17, 2014) Researchers are puzzled as to why obesity rates remain relatively stable as average waistlines continue to expand. Video provided by Newsy
Powered by NewsLook.com
President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com
Obama Orders Military Response to Ebola

Obama Orders Military Response to Ebola

AP (Sep. 16, 2014) Calling the Ebola outbreak in West Africa a potential threat to global security, President Barack Obama is ordering 3,000 U.S. military personnel to the stricken region amid worries that the outbreak is spiraling out of control. (Sept. 16) Video provided by AP
Powered by NewsLook.com
UN: 20,000 Could Be Infected With Ebola by Year End

UN: 20,000 Could Be Infected With Ebola by Year End

AFP (Sep. 16, 2014) Nearly $1.0 billion dollars is needed to fight the Ebola outbreak raging in west Africa, the United Nations say, warning that 20,000 could be infected by year end. Duration: 00:40 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins