Featured Research

from universities, journals, and other organizations

Scientists Use Old Enemy To K.O. Cancer

Date:
August 13, 2008
Source:
University of Warwick
Summary:
Chemists are pulling cancer onto a sucker punch by getting infected cells to drop their guard -- according to research published today. They are using the metal ruthenium as a catalyst to a cancer-busting reaction which calls up an old cellular enemy -- oxidants -- as an ally.

Chemists are pulling cancer onto a sucker punch by getting infected cells to drop their guard – according to new research. They are using the metal ruthenium as a catalyst to a cancer-busting reaction which calls up an old cellular enemy – oxidants – as an ally.

Related Articles


Cancer adapts quickly to traditional drugs which attack infected cells directly. But the latest laboratory tests reveal a second line of defence using ruthenium as a catalyst to a reaction which stops cells developing the anti-oxidant chemical glutathione.

As the targeted cell is forced to drop its glutathione defences, the oxidant levels increase, and the cancerous cell dies.

University of Warwick Chemistry Professor Peter Sadler explained: "We know oxidants produce free radicals that damage cells. Our experiments show ruthenium produces a reaction in the cell which destroys its anti-oxidant defence glutathione – thus destroying the cancer-infected cell.

"Working with colleagues in Edinburgh University and Oncosense we've proved this could be an effective line of defence against cancer."

Scientists working on the project now hope to move the research out of the laboratory – the next stage for this work would be medical trials.

The research was funded the Biotechnology and Biological Sciences Research Council (BBSRC), and the findings are published in the Proceedings of the National Academy of Sciences - August 2008.


Story Source:

The above story is based on materials provided by University of Warwick. Note: Materials may be edited for content and length.


Cite This Page:

University of Warwick. "Scientists Use Old Enemy To K.O. Cancer." ScienceDaily. ScienceDaily, 13 August 2008. <www.sciencedaily.com/releases/2008/08/080812135650.htm>.
University of Warwick. (2008, August 13). Scientists Use Old Enemy To K.O. Cancer. ScienceDaily. Retrieved January 26, 2015 from www.sciencedaily.com/releases/2008/08/080812135650.htm
University of Warwick. "Scientists Use Old Enemy To K.O. Cancer." ScienceDaily. www.sciencedaily.com/releases/2008/08/080812135650.htm (accessed January 26, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, January 26, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Mistakes Should Serve a Lesson Says WHO

Ebola Mistakes Should Serve a Lesson Says WHO

AFP (Jan. 25, 2015) The World Health Organization&apos;s chief on Sunday admitted the UN agency had been caught napping on Ebola, saying it should serve a lesson to avoid similar mistakes in future. Duration: 00:55 Video provided by AFP
Powered by NewsLook.com
Disneyland Measles Outbreak Spreads To 5 States

Disneyland Measles Outbreak Spreads To 5 States

Newsy (Jan. 24, 2015) Much of the Disneyland measles outbreak is being blamed on the anti-vaccination movement. The CDC encourages just about everyone get immunized. Video provided by Newsy
Powered by NewsLook.com
Growing Measles Outbreak Worries Calif. Parents

Growing Measles Outbreak Worries Calif. Parents

AP (Jan. 23, 2015) Public health officials are rushing to contain a measles outbreak that has sickened 70 people across 6 states and Mexico. The AP&apos;s Raquel Maria Dillon has more. (Jan. 23) Video provided by AP
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins