Featured Research

from universities, journals, and other organizations

Scientists Use Old Enemy To K.O. Cancer

Date:
August 13, 2008
Source:
University of Warwick
Summary:
Chemists are pulling cancer onto a sucker punch by getting infected cells to drop their guard -- according to research published today. They are using the metal ruthenium as a catalyst to a cancer-busting reaction which calls up an old cellular enemy -- oxidants -- as an ally.

Chemists are pulling cancer onto a sucker punch by getting infected cells to drop their guard – according to new research. They are using the metal ruthenium as a catalyst to a cancer-busting reaction which calls up an old cellular enemy – oxidants – as an ally.

Cancer adapts quickly to traditional drugs which attack infected cells directly. But the latest laboratory tests reveal a second line of defence using ruthenium as a catalyst to a reaction which stops cells developing the anti-oxidant chemical glutathione.

As the targeted cell is forced to drop its glutathione defences, the oxidant levels increase, and the cancerous cell dies.

University of Warwick Chemistry Professor Peter Sadler explained: "We know oxidants produce free radicals that damage cells. Our experiments show ruthenium produces a reaction in the cell which destroys its anti-oxidant defence glutathione – thus destroying the cancer-infected cell.

"Working with colleagues in Edinburgh University and Oncosense we've proved this could be an effective line of defence against cancer."

Scientists working on the project now hope to move the research out of the laboratory – the next stage for this work would be medical trials.

The research was funded the Biotechnology and Biological Sciences Research Council (BBSRC), and the findings are published in the Proceedings of the National Academy of Sciences - August 2008.


Story Source:

The above story is based on materials provided by University of Warwick. Note: Materials may be edited for content and length.


Cite This Page:

University of Warwick. "Scientists Use Old Enemy To K.O. Cancer." ScienceDaily. ScienceDaily, 13 August 2008. <www.sciencedaily.com/releases/2008/08/080812135650.htm>.
University of Warwick. (2008, August 13). Scientists Use Old Enemy To K.O. Cancer. ScienceDaily. Retrieved August 1, 2014 from www.sciencedaily.com/releases/2008/08/080812135650.htm
University of Warwick. "Scientists Use Old Enemy To K.O. Cancer." ScienceDaily. www.sciencedaily.com/releases/2008/08/080812135650.htm (accessed August 1, 2014).

Share This




More Health & Medicine News

Friday, August 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins