Featured Research

from universities, journals, and other organizations

Breast Cancer Survivors Have High Quality Of Life Up To 15 Years After Lumpectomy And Radiation

Date:
September 23, 2008
Source:
Fox Chase Cancer Center
Summary:
Women with breast cancer who are treated with lumpectomy and radiation report a high level of overall quality of life several years after treatment that is comparable to a general sampling of the adult women US population according to a survey conducted by physicians at Fox Chase Cancer Center.

Women with breast cancer who are treated with lumpectomy and radiation report a high level of overall quality of life several years after treatment that is comparable to a general sampling of the adult women U.S. population according to a survey conducted by physicians at Fox Chase Cancer Center.

"Treatments for breast cancer may decrease quality of life temporarily, but this is evidence that survivors on average will return to a normal quality of life," said Gary Freedman, M.D., an attending physician in the department of radiation oncology at Fox Chase Cancer Center who led the survey. Freedman's research was presented today at the 50th annual meeting of the American Society for Therapeutic Radiology and Oncology.

The study included women with early stage breast cancer treated with breast-conserving surgery and radiation with or without chemotherapy and hormone therapy. During routine follow-up visits with their oncologist, the women were asked to complete a brief questionnaire. Of the 1,050 women surveyed, 32 percent submitted 1 survey, 29 percent submitted 2, 21 percent submitted 3 and 18 percent submitted 4 or more surveys. The women were at various points in their follow-up -- from 3 months to 15 years after treatment. The mean follow-up time between treatment and the survey (midway between the two extremes) was 3 years.

The survey tool used is called EQ-5D, a standardized and validated instrument for measuring health outcomes. There are 5 general questions about health including questions about mobility, self-care, anxiety/depression, pain/discomfort, and ability to perform usual activities. The survey allows for three possible levels of response (1 = no problems, 2 = some problems, or 3 = extreme problems). The answers are combined to determine a health state for each woman at the time of the survey. Considering the 5 questions and 3 possible answers for each, there were 243 possible health states. An index number between 0 and 1 was assigned to each health state. The index scores gathered in this survey were compared to a survey of the general U.S. adult population (Luo et al Med Care 2005; 43:1078-86).

There were no significant differences in health states between patients by age. The mean index score 5 years after treatment was 0.95 for women ages 18󈞘, 0.90 for women ages 45󈞬, and 0.88 for women older than 64. The mean index score 10 years after treatment was 0.96 for women ages 18󈞘, 0.93 for women ages 45󈞬, and 0.76 for women older than 64.

By comparison, the reported mean index scores for the general U.S. female population by age is 0.91 for ages 18-44, 0.84 for ages 45-64, and 0.81 for women over 64.

"These data appear to show breast cancer survivors have a very high quality of life when compared to the general population," said Freedman.

He added that in four of the five questions, a statistically significant trend was observed with the women moving between none or some problems over the years following treatment. For the question regarding self care, the patients trend up, moving from "no problems" to "some problems." For 3 of the questions—anxiety, pain and ability to do usual activities-- patients reported improved health states from "some problems" to "no problems."

There were very few women (less than 5 percent) reporting extreme problems with pain, usual activity or self care.

"The brevity of this survey with its 5 questions and 3 possible responses for each, allows us to conduct it quickly in the clinical setting with more patients," Freedman explained. "However, the survey is a general measure of quality of life and does not include information on all possible side effects, such as lymphedema or if the women are happy with their breast appearance."

In addition to Freedman, other authors include Penny Anderson, Tianyu Li, Nicos Nicolaou and Andre Konski of Fox Chase Cancer Center. The authors report no disclosures.


Story Source:

The above story is based on materials provided by Fox Chase Cancer Center. Note: Materials may be edited for content and length.


Cite This Page:

Fox Chase Cancer Center. "Breast Cancer Survivors Have High Quality Of Life Up To 15 Years After Lumpectomy And Radiation." ScienceDaily. ScienceDaily, 23 September 2008. <www.sciencedaily.com/releases/2008/09/080921162006.htm>.
Fox Chase Cancer Center. (2008, September 23). Breast Cancer Survivors Have High Quality Of Life Up To 15 Years After Lumpectomy And Radiation. ScienceDaily. Retrieved September 23, 2014 from www.sciencedaily.com/releases/2008/09/080921162006.htm
Fox Chase Cancer Center. "Breast Cancer Survivors Have High Quality Of Life Up To 15 Years After Lumpectomy And Radiation." ScienceDaily. www.sciencedaily.com/releases/2008/09/080921162006.htm (accessed September 23, 2014).

Share This



More Health & Medicine News

Tuesday, September 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Liberia Pleads for Help to Fight Ebola

Liberia Pleads for Help to Fight Ebola

AP (Sep. 22, 2014) Liberia's finance minister is urging the international community to quickly follow through on pledges of cash to battle Ebola. Bodies are piling up in the capital Monrovia as the nation awaits more help. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Ebola Doctor Says Border Controls Critical

Ebola Doctor Says Border Controls Critical

AP (Sep. 22, 2014) A Florida doctor who helped fight the expanding Ebola outbreak in West Africa says the disease can be stopped, but only if nations quickly step up their response and make border control a priority. (Sept. 22) Video provided by AP
Powered by NewsLook.com
Global Ebola Aid Increasing But Critics Say It's Late

Global Ebola Aid Increasing But Critics Say It's Late

Newsy (Sep. 21, 2014) More than 100 tons of medical supplies were sent to West Africa on Saturday, but aid workers say the global response is still sluggish. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Lockdown to Control Ebola

Sierra Leone in Lockdown to Control Ebola

AP (Sep. 21, 2014) Sierra Leone residents remained in lockdown on Saturday as part of a massive effort to confine millions of people to their homes in a bid to stem the biggest Ebola outbreak in history. (Sept. 20) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins