Featured Research

from universities, journals, and other organizations

Fading Sense Of Smell May Signal Onset Of Parkinson's Disease

Date:
December 11, 2008
Source:
Northwestern Memorial Hospital
Summary:
Many individuals with Parkinson's disease are able to recall losing their sense of smell well before the onset of more commonly recognized symptoms such as tremors, impaired dexterity, speech problems, memory loss and decreased cognitive ability. To determine if a fading sense of smell may signal Parkinson's, researchers are participating in a national study to examine the correlation.

Many individuals with Parkinson's disease are able to recall losing their sense of smell well before the onset of more commonly recognized symptoms such as tremors, impaired dexterity, speech problems, memory loss and decreased cognitive ability.

Related Articles


To determine if a fading sense of smell may signal Parkinson's, researchers at Northwestern Memorial Hospital and Northwestern University's Feinberg School of Medicine are participating in a national study to examine the correlation and ascertain whether smell loss presents a tool for early detection of the disease and an opportunity to delay or ultimately prevent more troublesome symptoms.

Nearly one million people in the United States are affected by Parkinson's disease, which stems from premature aging of dopamine-producing cells in the brain, and the number is likely to grow as the population ages. By the time Parkinson's disease is detected, most individuals have already experienced a 60 to 70 percent loss of dopamine-producing cells in the brain.

"Very little is known about the early stages of this disease," says Tanya Simuni, MD, director of Northwestern's Parkinson's Disease and Movement Disorders Center and Associate Professor of Neurology at Northwestern University's Feinberg School of Medicine. "By utilizing smell testing in conjunction with other tests, we hope to develop a system that identifies the presence of Parkinson's before it develops into problematic symptoms."

Northwestern is one of 15 sites nationwide and the only center in Illinois to participate in the Parkinson's Associated Risk Study (PARS), the largest long-term study in the United States of relatives of individuals with Parkinson's disease. Evaluating 7,500 relatives for three to five years, the study draws from research demonstrating that first-degree family members such as mothers, fathers, siblings or children have a slight increase in their risk to develop the disease. As age has been recognized as the single proven risk factor for the onset of Parkinson's symptoms, the study will monitor relatives 50 years or older.

PARS study participants will be sent a scratch-and-sniff test accompanied by a brief questionnaire to be completed at home, with possible follow-up through continued questionnaires or evaluation by a local neurologist. Participants may also be contacted for more extensive testing.

"This study presents an enormous opportunity to not only better understand the initial stages of Parkinson's, but also help future generations," says Dr. Simuni. "In the future, early detection combined with neuroprotective therapy may pave the way for interventions that slow the progression or even prevent the onset of Parkinson's disease."


Story Source:

The above story is based on materials provided by Northwestern Memorial Hospital. Note: Materials may be edited for content and length.


Cite This Page:

Northwestern Memorial Hospital. "Fading Sense Of Smell May Signal Onset Of Parkinson's Disease." ScienceDaily. ScienceDaily, 11 December 2008. <www.sciencedaily.com/releases/2008/12/081211152516.htm>.
Northwestern Memorial Hospital. (2008, December 11). Fading Sense Of Smell May Signal Onset Of Parkinson's Disease. ScienceDaily. Retrieved December 21, 2014 from www.sciencedaily.com/releases/2008/12/081211152516.htm
Northwestern Memorial Hospital. "Fading Sense Of Smell May Signal Onset Of Parkinson's Disease." ScienceDaily. www.sciencedaily.com/releases/2008/12/081211152516.htm (accessed December 21, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, December 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Touch-Free Smart Phone Empowers Mobility-Impaired

Touch-Free Smart Phone Empowers Mobility-Impaired

Reuters - Innovations Video Online (Dec. 21, 2014) A touch-free phone developed in Israel enables the mobility-impaired to operate smart phones with just a movement of the head. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Earthworms Provide Cancer-Fighting Bacteria

Earthworms Provide Cancer-Fighting Bacteria

Reuters - Innovations Video Online (Dec. 21, 2014) Polish scientists isolate bacteria from earthworm intestines which they say may be used in antibiotics and cancer treatments. Suzannah Butcher reports. Video provided by Reuters
Powered by NewsLook.com
Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Existing Chemical Compounds Could Revive Failing Antibiotics, Says Danish Scientist

Reuters - Innovations Video Online (Dec. 21, 2014) A team of scientists led by Danish chemist Jorn Christensen says they have isolated two chemical compounds within an existing antipsychotic medication that could be used to help a range of failing antibiotics work against killer bacterial infections, such as Tuberculosis. Jim Drury went to meet him. Video provided by Reuters
Powered by NewsLook.com
Hugging It Out Could Help You Ward Off A Cold

Hugging It Out Could Help You Ward Off A Cold

Newsy (Dec. 21, 2014) Carnegie Mellon researchers found frequent hugs can help people avoid stress-related illnesses. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins