Featured Research

from universities, journals, and other organizations

High Dosage Brachytherapy Obtains Excellent Results In Head And Neck Tumors

Date:
April 4, 2009
Source:
Basque Research
Summary:
High-dosage perioperative brachytherapy (applied within the surgical process) obtains excellent results in the treatment of head and neck tumors, at the same time as reducing the period of radiation.

High-dosage perioperative brachytherapy (applied within the surgical process) obtains excellent results in the treatment of head and neck tumours, at the same time as reducing the period of radiation. These are the conclusions of research undertaken jointly by three Departments at the University of Navarra Hospital and which was published in the latest issue of Brachytherapy.

Related Articles


The work describes the application of this new radiotherapy technique to 40 patients between 2000 and 2006. Given the size of the sample, the article is a description of the greatest number of patients treated with high-dosage brachytherapy for head and neck tumours in world medical literature. According to results, after a seven-year follow-up, the illness was controlled in 86% of the cases and the percentage of survival was 52%.

In concrete, the research focused on the treatment of tumours in the oral cavity, those affecting the tongue and the floor of the mouth, and those in the oropharyngeal region, such as tumours of the tonsils.

Involved in the study was a multidisciplinary team of seven specialists from three departments at the University of Navarra Hospital: the Radiotherapy Department, the Department of Oral and Maxillofacial Surgery and the Ear, Nose and Throat Department.

Intensifying radiation dosage

As is known, brachytherapy is a radiotherapy treatment involving the placing of radioactive sources within the tumour or nearby.

In the case in hand, the work analysed the application of brachytherapy as complementary post-surgery treatment, explained Doctor Rafael Martínez-Monge, Director of the Radiotherapy Department. Some cases of head and neck tumours require the application of radiotherapy after the surgical operation. Using this technique, they have managed to intensify the radiation dosage with the goal of reducing relapse rates.

In certain treatments, brachytherapy provides better end-result possibilities than conventional radiotherapy. The procedure enables the administration of doses that would not be easily achieved using other techniques, due to toxic effects, explained the specialist from the University of Navarra Hospital.

Two weeks of treatment less

Moreover, the use in brachytherapy of high dosages involves a series of benefits for the patient as regards the overall treatment. The great advantage, points out Doctor Martínez-Monge, is the reduction of total time. While conventional radiotherapy treatment lasted seven weeks, administering part of the radiation through brachytherapy can take two weeks less.

This technique also manages to reduce the time of radiation compared to treatment with low dosage brachytherapy. Thanks to the existence of new sources of radiation, the treatment is released in a matter of minutes. Before the patient under brachytherapy treatment carried the radioactive source for several days and, thus, had to be isolated in a lead-lined room, with limitations on visits and nursing care. With high-dosage brachytherapy, however, the patient is only radioactive during the actual administration of the treatment; as such, the rest of the time can be spent in a conventional room.

For the administration of this technique it is necessary to prepare the affected region during the surgical operation. On extirpating the tumour, the surgeon covers the surgery zone — the area with greatest possibilities for relapse — with a series of plastic tubes which are subsequently filled with radioactive material, the aim being to effect a highly selective and precise radiation. Brachytherapy is introduced through these tubes, one end of which appears at the surface of the skin, like a drainpipe, explained Doctor Rafael Martínez-Monge. These tubes are connected to a machine that administers the treatment according to a computer programme personalised for each patient, he added.

Application to other types of tumour

Apart from perioperative high-dosage brachytherapy treatment for head and neck tumours, the University of Navarra Hospital has been working on the application of this procedure to other oncological processes for a number of years. There are a number of studies under way on its use in gynaecological tumours and sarcomas, amongst others. Since 2000 about 400 patients, with different types of tumours, have been treated with this technique.


Story Source:

The above story is based on materials provided by Basque Research. Note: Materials may be edited for content and length.


Cite This Page:

Basque Research. "High Dosage Brachytherapy Obtains Excellent Results In Head And Neck Tumors." ScienceDaily. ScienceDaily, 4 April 2009. <www.sciencedaily.com/releases/2009/03/090327112545.htm>.
Basque Research. (2009, April 4). High Dosage Brachytherapy Obtains Excellent Results In Head And Neck Tumors. ScienceDaily. Retrieved March 30, 2015 from www.sciencedaily.com/releases/2009/03/090327112545.htm
Basque Research. "High Dosage Brachytherapy Obtains Excellent Results In Head And Neck Tumors." ScienceDaily. www.sciencedaily.com/releases/2009/03/090327112545.htm (accessed March 30, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, March 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

S. Leone in New Anti-Ebola Lockdown

S. Leone in New Anti-Ebola Lockdown

AFP (Mar. 28, 2015) — Sierra Leone imposed a three-day nationwide lockdown Friday for the second time in six months in a bid to prevent a resurgence of the deadly Ebola virus. Duration: 01:17 Video provided by AFP
Powered by NewsLook.com
These Popular Antibiotics Can Cause Permanent Nerve Damage

These Popular Antibiotics Can Cause Permanent Nerve Damage

Newsy (Mar. 27, 2015) — A popular class of antibiotic can leave patients in severe pain and even result in permanent nerve damage. Video provided by Newsy
Powered by NewsLook.com
Sierra Leone in Ebola Lockdown

Sierra Leone in Ebola Lockdown

Reuters - News Video Online (Mar. 27, 2015) — Millions of people in Sierra Leone are urged to stay at home in a three-day lockdown to help end the country&apos;s Ebola outbreak. Paul Chapman reports. Video provided by Reuters
Powered by NewsLook.com
WH Plan to Fight Antibiotic-Resistant Germs

WH Plan to Fight Antibiotic-Resistant Germs

AP (Mar. 27, 2015) — The White House on Friday announced a five-year plan to fight the threat posed by antibiotic-resistant bacteria amid fears that once-treatable germs could become deadly. (March 27) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins