Featured Research

from universities, journals, and other organizations

Fast Release Of Data Leads To Rapid Changes In Clinical Practice For Drug-eluting Stents

Date:
July 28, 2009
Source:
American Heart Association
Summary:
Use of drug-eluting stents dropped from 90 percent of all stents to less than 60 percent after negative data were released and publicized. Medical information distributed by e-mail, smart phones and other new technologies has led to rapid changes to medical practice. New processes are needed to help physicians and patients filter through instant medical information and put research into context.

E-mail, search engines, smart phones and other new technologies that can disseminate new medical information quickly led to an almost immediate change in clinical practice for drug-eluting stents, according to a study reported in Circulation: Cardiovascular Quality and Outcomes.

Related Articles


With the rapid-fire release of data, studies presented at medical conferences in the age of instant information can have an almost immediate impact on patient treatment, said Matthew T. Roe, M.D., M.H.S., lead author of the study and associate professor of medicine at Duke University Medical Center and at the Duke Clinical Research Institute in Durham N.C.

“We were interested in whether practice patterns changed after the presentation of these studies,” he said. “That’s indeed what we showed.”

Researchers examined data from two large patient registries that showed from January - September 2006 (before the data were released) about 90 percent of patients with a type of heart attack known as a non-ST-elevation myocardial infarction (NSTEMI) who underwent coronary stent implantation received drug-eluting stents, which are coated with anti-proliferative drugs to prevent narrowings from recurring within the coronary arteries.

In September 2006, a number of studies were presented at the European Society of Cardiology Scientific Sessions that found drug-coated stents were associated with a higher risk of late stent thrombosis, or blood clots in the artery treated with the stent, compared with bare metal stents which were not coated with anti-proliferative drugs. By the end of March 2007, the use of drug-eluting stents fell to 67 percent and usage continued to drop to 58 percent by the beginning of 2008, Roe said. “There was a rapid change of practice patterns after these presentations in September 2006,” he said.

“To our knowledge, this was the most rapid change in practice patterns in cardiology. We presume it was because of a rapid uptake of information.”

The swiftness in which practice patterns changed signaled that speedy distribution of information through media and scientific outlets may become the “predominant stimulus for changes in practice in the future,” researchers said.

Researchers examined records of 54,662 patients with NSTEMI, which included 27,329 patients who had stents implanted. The information was gathered from two large registries: CRUSADE (Can Rapid risk stratification of Unstable angina patients Suppress ADverse outcomes with Early implementation of the ACC/AHA guidelines) during 2006, which transitioned into ACTION Registry–GWTG (Get With the Guidelines) beginning in January, 2007. Hospital or patient characteristics didn’t change during the study, researchers said.

The study’s results show the need for experts to put results in context, Roe said.

“This study demonstrates the dynamic shifts that are occurring in the distribution of medical information,” said Clyde W. Yancy, M.D. president of the American Heart Association and medical director at Baylor Heart and Vascular Institute in Dallas, Texas. “The opportunity to widely share important findings that promptly impact practice is becoming a powerful tool to drive change. The requirements for prompt but thorough peer review and nimble responsiveness to new data are evident. Managing this new health IT space will require focus, assessment and realignment.”

Co-authors are: Anita Y. Chen, M.S.; Christopher P. Cannon, M.D.; Sunil Rao, M.D.; John Rumsfeld, M.D., Ph.D.; David J. Magid, M.D., M.P.H.; Ralph Brindis, M.D., M.P.H.; Lloyd W. Klein, M.D.; W. Brian Gibler, M.D.; E. Magnus Ohman, M.D.; and Eric D. Peterson, M.D., M.P.H.


Story Source:

The above story is based on materials provided by American Heart Association. Note: Materials may be edited for content and length.


Cite This Page:

American Heart Association. "Fast Release Of Data Leads To Rapid Changes In Clinical Practice For Drug-eluting Stents." ScienceDaily. ScienceDaily, 28 July 2009. <www.sciencedaily.com/releases/2009/07/090728170954.htm>.
American Heart Association. (2009, July 28). Fast Release Of Data Leads To Rapid Changes In Clinical Practice For Drug-eluting Stents. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2009/07/090728170954.htm
American Heart Association. "Fast Release Of Data Leads To Rapid Changes In Clinical Practice For Drug-eluting Stents." ScienceDaily. www.sciencedaily.com/releases/2009/07/090728170954.htm (accessed November 28, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, November 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola Leaves Orphans Alone in Sierra Leone

Ebola Leaves Orphans Alone in Sierra Leone

AFP (Nov. 27, 2014) — The Ebola epidemic sweeping Sierra Leone is having a profound effect on the country's children, many of whom have been left without any family members to support them. Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Experimental Ebola Vaccine Shows Promise In Human Trial

Experimental Ebola Vaccine Shows Promise In Human Trial

Newsy (Nov. 27, 2014) — A recent test of a prototype Ebola vaccine generated an immune response to the disease in subjects. Video provided by Newsy
Powered by NewsLook.com
Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) — Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
Today's Prostheses Are More Capable Than Ever

Today's Prostheses Are More Capable Than Ever

Newsy (Nov. 26, 2014) — Advances in prosthetics are making replacement body parts stronger and more lifelike than they’ve ever been. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins