Featured Research

from universities, journals, and other organizations

Holocaust Survivors At Higher Risk For All Cancers

Date:
October 27, 2009
Source:
Journal of the National Cancer Institute
Summary:
Jewish survivors of World War II who were potentially exposed to the Holocaust are at a higher risk for cancer occurrence, according to a new study.

Jewish survivors of World War II who were potentially exposed to the Holocaust are at a higher risk for cancer occurrence, according to a new study published online October 26 in the Journal of the National Cancer Institute.

Previous studies, in non-Jewish populations, investigating the relationship of cancer incidence rates to physical and psychological stress, such as famine and mental stress, have reached inclusive results.

To further investigate the relationship, Lital Keinan-Boker, M.D., Ph.D., MPH, of the School of Public Health, Faculty of Welfare and Health Sciences, at the University of Haifa in Israel, and colleagues compared the cancer rates in a cohort of over 300,000 Israeli Jews who were born in Europe and immigrated to Israel before or during World War II (the non-exposed group) with cancer rates in a cohort of European-born Israeli Jews who immigrated from Europe after World War II and up to 1989 (the exposed group, those potentially exposed to the Holocaust). Exposure was based on immigration dates because no individual data were available on actual Holocaust exposure.

Likely exposure, compared with non-exposure, was associated with statistically significantly increased risk for overall cancer risk (all cancers combined) for all birth cohorts, and for both sexes. The strongest associations were with breast and colorectal cancer. Earlier exposure, i.e., at a younger age, seemed to be particularly associated with increased risk of all-site cancer.

"These observations may have direct impact on the health of World War II Jewish survivors and thus the care required from their caregivers in Israel and elsewhere," the authors write. "These findings warrant further epidemiological studies (such as case-control studies) of past and present risk factors that use individual data."

In an accompanying editorial, Stephen D. Hursting, Ph.D, MPH, of the Department of Nutritional Sciences at the University of Texas, Austin, and Michele R. Forman, Ph.D., of the Department of Epidemiology, University of Texas -- MD Anderson Cancer Center in Houston, discuss these results in European-born Israeli Jews and those of several past studies of calorie reduction and cancer risk. They say the data from this study add to the growing body of literature on the effects of severely restricted calorie intake and of unimaginable psychosocial and physical hardships on cancer risk.

"Taken together, data from animal and human studies suggest that while [calorie reduction] typically decreases cancer risk, the anticancer effects of [calorie reduction] may be neutralized or overwhelmed in the presence of extreme stressors," the editorialists write. "From this unique cohort we can learn lessons about adaptation to extreme hardships in early life, resilience during life, and cancer susceptibility later in life."


Story Source:

The above story is based on materials provided by Journal of the National Cancer Institute. Note: Materials may be edited for content and length.


Cite This Page:

Journal of the National Cancer Institute. "Holocaust Survivors At Higher Risk For All Cancers." ScienceDaily. ScienceDaily, 27 October 2009. <www.sciencedaily.com/releases/2009/10/091026161840.htm>.
Journal of the National Cancer Institute. (2009, October 27). Holocaust Survivors At Higher Risk For All Cancers. ScienceDaily. Retrieved September 17, 2014 from www.sciencedaily.com/releases/2009/10/091026161840.htm
Journal of the National Cancer Institute. "Holocaust Survivors At Higher Risk For All Cancers." ScienceDaily. www.sciencedaily.com/releases/2009/10/091026161840.htm (accessed September 17, 2014).

Share This



More Health & Medicine News

Wednesday, September 17, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Artificial Sweetener Could Promote Diabetes

Artificial Sweetener Could Promote Diabetes

Newsy (Sep. 17, 2014) Doctors once thought artificial sweeteners lacked the health risks of sugar, but a new study says they can impact blood sugar levels the same way. Video provided by Newsy
Powered by NewsLook.com
Ebola Vaccine Trial Gets Underway at Oxford University

Ebola Vaccine Trial Gets Underway at Oxford University

AFP (Sep. 17, 2014) A healthy British volunteer is to become the first person to receive a new vaccine for the Ebola virus after US President Barack Obama called for action against the epidemic and warned it was "spiralling out of control." Duration: 01:02 Video provided by AFP
Powered by NewsLook.com
Obesity Rates Steady Even As Americans' Waistlines Expand

Obesity Rates Steady Even As Americans' Waistlines Expand

Newsy (Sep. 17, 2014) Researchers are puzzled as to why obesity rates remain relatively stable as average waistlines continue to expand. Video provided by Newsy
Powered by NewsLook.com
President To Send 3,000 Military Personnel To Fight Ebola

President To Send 3,000 Military Personnel To Fight Ebola

Newsy (Sep. 16, 2014) President Obama is expected to send 3,000 troops to West Africa as part of the effort to contain Ebola's spread. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins