Featured Research

from universities, journals, and other organizations

Physician urges changes in diagnosis for sore throat in young adults

Date:
December 27, 2009
Source:
University of Alabama at Birmingham
Summary:
New analysis suggests that physicians need to re-think their diagnosis and treatment of sore throat, or pharyngitis, in adolescents and young adults to consider a more newly identified and potentially dangerous culprit as the source of that infection.

New analysis from the University of Alabama at Birmingham (UAB) suggests that physicians need to re-think their diagnosis and treatment of sore throat, or pharyngitis, in adolescents and young adults to consider a more newly identified and potentially dangerous culprit as the source of that infection.

Currently, physicians are taught to suspect group A streptococcal bacteria as the primary cause of pharyngitis. But according to findings published Dec. 1 in the Annals of Internal Medicine, physicians also should look for the presence of bacteria called Fusobacterium necrophorum when treating sore throat in young adults and adolescents that worsens or is strep-negative.

"F. necrophorum, which only has been recognized as a potential cause of pharyngitis in adolescents and young adults in the past five years, may cause up to 10 percent of sore throat in those 15-24 years of age," said Robert Centor, M.D., professor of internal medicine, associate dean of medicine at UAB and the paper's lead author. "More important, F. necrophorum is associated with a rare but life-threatening complication called Lemierre syndrome."

Lemierre syndrome mostly affects adolescents and young adults and rarely is seen in pre-adolescents. It begins with a sore throat, followed by an infected jugular vein after four to five days. Abscesses in other parts of the body may occur. Approximately 5 percent of people who get Lemierre syndrome die.

Group A strep also is associated with a serious complication -- rheumatic fever -- but the incidence rate of Lemierre syndrome following exposure to F. necrophorum is much higher and associated with greater morbidity and mortality.

"The risk of Lemierre syndrome exceeds the risk of acute rheumatic fever, which is the classic reason that physicians worry about sore throats," said Centor.

Centor said clinicians should expand their diagnostic process for adolescents and young adults with sore throat to consider F. necrophorum, especially if the sore throat does not improve within three to five days. Centor said physicians need to be aware of the red flags that might indicate Lemierre syndrome, including unilateral neck swelling, rigors, night sweats or high fevers. There is not a routine test for F. necrophorum pharyngitis and a CT scan is required to detect Lemierre syndrome

Aggressive treatment with antibiotics such as a combination of penicillin and metronidazole or with clindamycin alone is appropriate. Centor said he hopes this analysis will lead to better diagnostic tests for the presence of F. necrophorum.


Story Source:

The above story is based on materials provided by University of Alabama at Birmingham. Note: Materials may be edited for content and length.


Cite This Page:

University of Alabama at Birmingham. "Physician urges changes in diagnosis for sore throat in young adults." ScienceDaily. ScienceDaily, 27 December 2009. <www.sciencedaily.com/releases/2009/11/091130192924.htm>.
University of Alabama at Birmingham. (2009, December 27). Physician urges changes in diagnosis for sore throat in young adults. ScienceDaily. Retrieved July 28, 2014 from www.sciencedaily.com/releases/2009/11/091130192924.htm
University of Alabama at Birmingham. "Physician urges changes in diagnosis for sore throat in young adults." ScienceDaily. www.sciencedaily.com/releases/2009/11/091130192924.htm (accessed July 28, 2014).

Share This




More Health & Medicine News

Monday, July 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Trees Could Save More Than 850 Lives Each Year

Trees Could Save More Than 850 Lives Each Year

Newsy (July 27, 2014) A national study conducted by the USDA Forest Service found that trees collectively save more than 850 lives on an annual basis. Video provided by Newsy
Powered by NewsLook.com
Google's Next Frontier: The Human Body

Google's Next Frontier: The Human Body

Newsy (July 27, 2014) Google is collecting genetic and molecular information to paint a picture of the perfectly healthy human. Video provided by Newsy
Powered by NewsLook.com
What's To Blame For Worst Ebola Outbreak In History?

What's To Blame For Worst Ebola Outbreak In History?

Newsy (July 27, 2014) A U.S. doctor has tested positive for the deadly Ebola virus, as the worst-ever outbreak continues to grow. Video provided by Newsy
Powered by NewsLook.com
Losing Sleep Leaves You Vulnerable To 'False Memories'

Losing Sleep Leaves You Vulnerable To 'False Memories'

Newsy (July 27, 2014) A new study shows sleep deprivation can make it harder for people to remember specific details of an event. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins