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Endoscopy-based research can affect quality of life in healthy volunteers?

Date:
February 4, 2010
Source:
World Journal of Gastroenterology
Summary:
A research team from Germany prospectively analyzed the impact of an endoscopy-based long-term research on the quality of life (QOL) in healthy volunteers. Their results demonstrated that an endoscopy-based drug trial has no significant influence on the QOL in healthy volunteers even under rigorous conditions and a long-term protocol.

The involvement of healthy volunteers (HV) in clinical and preclinical research, especially in the gastroenterology, has grown dramatically over the past few years. However, many issues of ethical, methodological or even legal concerns have not been systematically studied.

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A research article to be published on January 28, 2010 in the World Journal of Gastroenterology addresses this question. A research team lead by Professor Peter Malfertheiner, evaluated prospectively the changes in quality of life (QOL) in ten HV during a long-term endoscopy-based study.

The study was conducted strictly according to existing ethical recommendations and guidelines. Using the validated SF-36 survey and visual analog scale-based questionnaires, they showed that the research study with multiple endoscopic examinations and a long-term protocol did not or only minimally affected the QOL of HV.

This study provided valuable and important information regarding the QOL of HV who participate in endoscopy-based studies, and supported the existing recommendation and guidelines on this topic in Gastroenterology.


Story Source:

The above story is based on materials provided by World Journal of Gastroenterology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Link A, Treiber G, Peters B, Wex T, Malfertheiner P. Impact of endoscopy-based research on quality of life in healthy volunteers. World Journal of Gastroenterology, 2010; 16 (4): 467 DOI: 10.3748/wjg.v16.i4.467

Cite This Page:

World Journal of Gastroenterology. "Endoscopy-based research can affect quality of life in healthy volunteers?." ScienceDaily. ScienceDaily, 4 February 2010. <www.sciencedaily.com/releases/2010/02/100204101730.htm>.
World Journal of Gastroenterology. (2010, February 4). Endoscopy-based research can affect quality of life in healthy volunteers?. ScienceDaily. Retrieved November 28, 2014 from www.sciencedaily.com/releases/2010/02/100204101730.htm
World Journal of Gastroenterology. "Endoscopy-based research can affect quality of life in healthy volunteers?." ScienceDaily. www.sciencedaily.com/releases/2010/02/100204101730.htm (accessed November 28, 2014).

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