Featured Research

from universities, journals, and other organizations

Does smoking compound other multiple sclerosis risk factors?

Date:
April 8, 2010
Source:
American Academy of Neurology
Summary:
A new study shows that smoking may increase the risk of multiple sclerosis (MS) in people who also have specific established risk factors for MS.

A new study shows that smoking may increase the risk of multiple sclerosis (MS) in people who also have specific established risk factors for MS. The research is found in the April 7, 2010, online issue of Neurologyฎ, the medical journal of the American Academy of Neurology.

Related Articles


The research involved 442 people with MS and 865 people without the disease from three studies: the Nurses' Health Study I/Nurses' Health Study II, the Tasmanian MS Study and the Swedish MS Study. Researchers first determined whether participants had known risk factors for MS, including having a high level of antibody in the blood to the Epstein-Barr virus (a common herpes virus that infects most people but is associated with MS in a small fraction of those infected), or having an immune-system-related gene called the HLA-DR15 gene (which is present in 20% of the population at large but 60% of patients with MS).

The study found that among those with high levels of the antibody to the Epstein-Barr virus, smokers were twice as likely to have MS as those who had never smoked. The same association was not seen in those with low antibody levels. The risk of MS associated with smoking was not different in people with and without the HLA-DR15 gene.

"The consistency of an association between MS, smoking and the body's immune response to the Epstein-Barr virus based on these three distinct, geographically diverse studies suggests this finding is not due to chance," said study author Claire Simon, ScD, with Harvard School of Public Health in Boston. "This relationship may provide clues as to why certain individuals develop MS while others do not."

In the United States, the average lifetime risk of developing MS is approximately one in 200 for women and one in 600 for men. Among those with high antibody levels to the Epstein-barr virus, smokers may have up to a twofold increase in MS risk compared to non-smokers.

MS is the most common non‑traumatic disabling neurologic disease in the US among young adults

The study was supported by the National Institutes of Health, the National Health and Research Council of Australia, the Australian Rotary Health Research Fund and MS Australia.


Story Source:

The above story is based on materials provided by American Academy of Neurology. Note: Materials may be edited for content and length.


Journal Reference:

  1. Combined effects of smoking, anti-EBNA antibodies, and HLA-DRB1*1501 on multiple sclerosis risk. K. C. Simon, I. A.F. van der Mei, K. L. Munger, A. Ponsonby, J. Dickinson, T. Dwyer, P. Sundstr๖m, and A. Ascherio. Neurology, 2010; DOI: 10.1212/WNL.0b013e3181dad57e

Cite This Page:

American Academy of Neurology. "Does smoking compound other multiple sclerosis risk factors?." ScienceDaily. ScienceDaily, 8 April 2010. <www.sciencedaily.com/releases/2010/04/100407161734.htm>.
American Academy of Neurology. (2010, April 8). Does smoking compound other multiple sclerosis risk factors?. ScienceDaily. Retrieved December 18, 2014 from www.sciencedaily.com/releases/2010/04/100407161734.htm
American Academy of Neurology. "Does smoking compound other multiple sclerosis risk factors?." ScienceDaily. www.sciencedaily.com/releases/2010/04/100407161734.htm (accessed December 18, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Thursday, December 18, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) — As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) — A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) — Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) — Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins