Featured Research

from universities, journals, and other organizations

T cell protein boosts learning

Date:
May 4, 2010
Source:
Rockefeller University Press
Summary:
Stress, sickness and depression can generate inflammation in the brain, which is detrimental to learning. According to a new study T cells level the learning curve by producing a protein that combats inflammation, establishing a more learning-conducive environment in the brain.

Stress, sickness and depression can generate inflammation in the brain, which is detrimental to learning. According to a new study that will appear online on May 3rd in the Journal of Experimental Medicine, T cells level the learning curve by producing a protein that combats inflammation, establishing a more learning-conducive environment in the brain.

Related Articles


Learning defects had been reported in mice lacking T cells, but how these cells boosted brain power was unknown. A team led by Jonathan Kipnis (University of Virginia, Charlottesville) investigated the activity of these cells in mice trained to find their way through a water maze. Training the mice caused T cells to accumulate in the membrane that surrounds the brain. Once there, the cells produced a protein called interleukin-4 (IL-4), which reduced the abundance of inflammatory proteins known to hinder learning. Mice lacking IL-4 had a hard time navigating the maze, but their learning disability could be reversed by giving them IL-4-producing T cells.

It's not yet clear if IL-4 has similar effects in humans. If so, these findings could impact the design of new therapies aimed at boosting learning and memory in children with learning disabilities or adults with age-related dementia.


Story Source:

The above story is based on materials provided by Rockefeller University Press. Note: Materials may be edited for content and length.


Journal Reference:

  1. Derecki, N.C., et al. Meningeal immunity in learning and memory. he Journal of Experimental Medicine, DOI: 10.1084/jem.20091419

Cite This Page:

Rockefeller University Press. "T cell protein boosts learning." ScienceDaily. ScienceDaily, 4 May 2010. <www.sciencedaily.com/releases/2010/05/100503135428.htm>.
Rockefeller University Press. (2010, May 4). T cell protein boosts learning. ScienceDaily. Retrieved March 5, 2015 from www.sciencedaily.com/releases/2010/05/100503135428.htm
Rockefeller University Press. "T cell protein boosts learning." ScienceDaily. www.sciencedaily.com/releases/2010/05/100503135428.htm (accessed March 5, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Thursday, March 5, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Former NFL Players Donate Brains to Science

Former NFL Players Donate Brains to Science

Reuters - US Online Video (Mar. 3, 2015) Super Bowl champions Sidney Rice and Steve Weatherford donate their brains, post-mortem, to scientific research into repetitive brain trauma. Jillian Kitchener reports. Video provided by Reuters
Powered by NewsLook.com
Alzheimer's Protein Plaque Found In 20-Year-Olds

Alzheimer's Protein Plaque Found In 20-Year-Olds

Newsy (Mar. 3, 2015) Researchers found an abnormal protein associated with Alzheimer&apos;s disease in the brains of 20-year-olds. Video provided by Newsy
Powered by NewsLook.com
This Nasal Treatment Could Help Ease Migraine Pain

This Nasal Treatment Could Help Ease Migraine Pain

Newsy (Mar. 2, 2015) Researchers gave lidocaine to 112 patients, and about 88 percent of the subjects said they needed less migraine-relief medicine the next day. Video provided by Newsy
Powered by NewsLook.com
How Facebook Use Can Lead To Depression

How Facebook Use Can Lead To Depression

Newsy (Mar. 1, 2015) Margaret Duffy of the University of Missouri talks about her study on the social network and the envy and depression that Facebook use can cause. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins