Featured Research

from universities, journals, and other organizations

Receiving vaccine for pneumonia by men not associated with reduced risk of heart attack, stroke

Date:
May 4, 2010
Source:
JAMA and Archives Journals
Summary:
Men 45 years or older who received pneumococcal vaccine were not less likely to have a heart attack or stroke compared to men who did not receive the vaccine, according to a new study.

Men 45 years or older who received pneumococcal vaccine were not less likely to have a heart attack or stroke compared to men who did not receive the vaccine, according to a study in the May 5 issue of JAMA.

Hung Fu Tseng, Ph.D., of Kaiser Permanente Southern Califor¬nia, Pasadena, and colleagues conducted a study to examine the association between vaccination with pneumococcal vaccine and the risk of developing acute heart attack and stroke in men, taking into account known and potentially important confounders (factors that can influence a study, leading to unexpected outcomes that improperly skew the results).

The study included Kaiser Permanente Northern and Southern California health plans, with 84,170 participants ages 45 to 69 years from the California Men's Health Study, who were recruited between Janu¬ary 2002 and December 2003, and followed up until December 31, 2007. The cohort was similar to the population of health plan members and men who responded to a gen¬eral health survey in California on important demographic and clinical characteristics. Demographic and detailed lifestyle characteristics were collected from surveys. Vaccination records were obtained from the Kaiser Immunization Tracking System.

During follow-up, there were 1,211 first myocardial infarctions (MIs; heart attack) in vaccinated persons (rate of 10.7 per 1000 person-years) compared with 1,494 first MI events in unvaccinated individuals (6.07 per 1000 person-years). For stroke, there were 651 events in vaccinated persons (5.3 per 1000 person-years) compared with 483 events in unvaccinated persons (1.9 per 1000 person-years). After analysis of the data, the researchers found no evidence for an association between pneumococcal vaccination and reduced risk of acute MI or stroke. "In addition, association was not observed either in the current smokers, men with his¬tory of diabetes, men with history of hy¬pertension, or men of the low-risk group."

Editorial: Preventing Myocardial Infarction With Vaccination -- Myths and Realities

Mohammad Madjid, M.D., M.S., and Daniel M. Musher, M.D., of the Texas Heart Institute, St. Luke's Episcopal Hospital, and Bay¬lor College of Medicine, Houston, comment on the findings of this study.

"The study by Tseng et al is another important reminder of the complexities involved in evaluating observational stud¬ies examining the relationship between vaccine adminis¬tration and clinical outcomes, and the need for more robust study designs. Until rigorous data from clinical trials are available to determine whether pneumonia vaccine can prevent MI, physicians should strictly adhere to available guidelines for optimizing vaccination rates in recom¬mended target groups, because these rates are still far from optimal."


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal References:

  1. Hung Fu Tseng; Jeffrey M. Slezak; Virginia P. Quinn; Lina S. Sy; Stephen K. Van Den Eeden; Steven J. Jacobsen. Pneumococcal Vaccination and Risk of Acute Myocardial Infarction and Stroke in Men. JAMA, 2010; 303 (17): 1699-1706 [link]
  2. Mohammad Madjid; Daniel M. Musher. Preventing Myocardial Infarction With Vaccination: Myths and Realities. JAMA, 2010; 303 (17): 1751-1752 [link]

Cite This Page:

JAMA and Archives Journals. "Receiving vaccine for pneumonia by men not associated with reduced risk of heart attack, stroke." ScienceDaily. ScienceDaily, 4 May 2010. <www.sciencedaily.com/releases/2010/05/100504163111.htm>.
JAMA and Archives Journals. (2010, May 4). Receiving vaccine for pneumonia by men not associated with reduced risk of heart attack, stroke. ScienceDaily. Retrieved July 30, 2014 from www.sciencedaily.com/releases/2010/05/100504163111.htm
JAMA and Archives Journals. "Receiving vaccine for pneumonia by men not associated with reduced risk of heart attack, stroke." ScienceDaily. www.sciencedaily.com/releases/2010/05/100504163111.htm (accessed July 30, 2014).

Share This




More Health & Medicine News

Wednesday, July 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Generics Eat Into Pfizer's Sales

Generics Eat Into Pfizer's Sales

Reuters - Business Video Online (July 29, 2014) — Pfizer, the world's largest drug maker, cut full-year revenue forecasts because generics could cut into sales of its anti-arthritis drug, Celebrex. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com
Nigeria Ups Ebola Stakes on 1st Death

Nigeria Ups Ebola Stakes on 1st Death

Reuters - Business Video Online (July 29, 2014) — Nigerian authorities have shut and quarantined a Lagos hospital where a Liberian man died of the Ebola virus, the first recorded case of the highly-infectious disease in Africa's most populous economy. David Pollard reports Video provided by Reuters
Powered by NewsLook.com
Running 5 Minutes A Day Might Add Years To Your Life

Running 5 Minutes A Day Might Add Years To Your Life

Newsy (July 29, 2014) — According to a new study, just five minutes of running or jogging a day could add years to your life. Video provided by Newsy
Powered by NewsLook.com
Ebola Outbreak Poses Little Threat To U.S.: CDC

Ebola Outbreak Poses Little Threat To U.S.: CDC

Newsy (July 29, 2014) — The Ebola outbreak in West Africa poses little threat to Americans, according to officials with the Centers for Disease Control and Prevention. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins