Featured Research

from universities, journals, and other organizations

Knowledge gaps for 20 suspected carcinogens outlined

Date:
July 19, 2010
Source:
American Cancer Society
Summary:
A new report identifies gaps in research for 20 suspected carcinogens whose potential to cause cancer is as yet unresolved. The report is designed to prioritize agents for additional research, and to lead to well-planned epidemiologic or mechanistic studies leading to more definitive classification of these agents.

A new report from the American Cancer Society and other world-leading health groups identifies gaps in research for 20 suspected carcinogens whose potential to cause cancer is as yet unresolved. The report is designed to prioritize agents for additional research, and to lead to well-planned epidemiologic or mechanistic studies leading to more definitive classification of these agents.

The report, "Identification of research needs to resolve the carcinogenicity of high-priority IARC carcinogens," is a concerted effort to identify ways to close existing gaps in knowledge for particular agents classified by the International Agency for Research on Cancer (IARC) by identifying information needs and the research to address them for 20 selected agents. The agents are generally in IARC Groups 2A, 2B, and 3. The project originated as part of the National Institute for Occupational Safety and Health's (NIOSH) National Occupational Research Agenda (NORA) to enhance occupational cancer research, and involved collaboration with IARC, the American Cancer Society, the National Institute of Environmental Health Sciences (NIEHS), and the National Cancer Institute (NCI). The effort was co-sponsored by the American Cancer Society.

The agents prioritized as needing additional study are:

  • Lead and lead compounds
  • Indium phosphide
  • Cobalt with tungsten carbide
  • Titanium dioxide
  • Welding fumes
  • Refractory ceramic fibers
  • Diesel exhaust
  • Carbon black
  • Styrene-7,8-oxide and styrene
  • Propylene oxide
  • Formaldehyde
  • Acetaldehyde
  • Dichloromethane, methylene chloride (DCM)
  • Trichloroethylene (TCE)
  • Tetrachloroethylene (perc, tetra, PCE)
  • Chloroform
  • Polychlorinated biphenyls (PCBs)
  • Di(2-ethylhexyl) phthalate (DEHP)
  • Atrazine
  • Shift work

"There is significant concern among the public about substances or exposures in the environment that may cause cancer, and there are some common occupational agents and exposure circumstances where evidence of carcinogenicity is substantial but not yet conclusive for humans," said Elizabeth Ward, Ph. D., vice president, Surveillance and Health Policy Research at the American Cancer Society and lead author of the report.. "The objectives of this report are to identify research gaps and needs for 20 agents prioritized for review based on evidence of widespread human exposures and potential carcinogenicity in animals or humans." Dr. Ward, one of the organizers of the meeting and lead author of a version of the report that appears in the journal Environmental Health Perspectives, added that the report highlights the importance of research in occupational settings for the identification of human carcinogens as well as the need for funding and access to populations for this work to continue.


Story Source:

The above story is based on materials provided by American Cancer Society. Note: Materials may be edited for content and length.


Journal Reference:

  1. Elizabeth M. Ward, Paul A. Schulte, Kurt Straif, Nancy B. Hopf, Jane C. Caldwell, Tania Carreσn, David M. DeMarini, Bruce A. Fowler, Bernard D. Goldstein, Kari Hemminki, Kirsti Husgafvel Pursiainen, Eileen Kuempel, Joellen Lewtas, Ruth M. Lunn, Elsebeth Lynge, Damien M. McElvenny, Hartwig Muhle, Tamie Nakajima, Larry W. Robertson. Research Recommendations for Selected IARC-Classified Agents. Environmental Health Perspectives, 2010; DOI: 10.1289/ehp.0901828

Cite This Page:

American Cancer Society. "Knowledge gaps for 20 suspected carcinogens outlined." ScienceDaily. ScienceDaily, 19 July 2010. <www.sciencedaily.com/releases/2010/07/100715111430.htm>.
American Cancer Society. (2010, July 19). Knowledge gaps for 20 suspected carcinogens outlined. ScienceDaily. Retrieved September 30, 2014 from www.sciencedaily.com/releases/2010/07/100715111430.htm
American Cancer Society. "Knowledge gaps for 20 suspected carcinogens outlined." ScienceDaily. www.sciencedaily.com/releases/2010/07/100715111430.htm (accessed September 30, 2014).

Share This



More Health & Medicine News

Tuesday, September 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How 'Yes Means Yes' Defines Sexual Assault

How 'Yes Means Yes' Defines Sexual Assault

Newsy (Sep. 29, 2014) — Aimed at reducing sexual assaults on college campuses, California has adopted a new law changing the standard of consent for sexual activity. Video provided by Newsy
Powered by NewsLook.com
Scientists May Have Found An Early Sign Of Pancreatic Cancer

Scientists May Have Found An Early Sign Of Pancreatic Cancer

Newsy (Sep. 29, 2014) — Researchers looked at 1,500 blood samples and determined people who developed pancreatic cancer had more branched chain amino acids. Video provided by Newsy
Powered by NewsLook.com
Colo. Doctors See Cluster of Enterovirus Cases

Colo. Doctors See Cluster of Enterovirus Cases

AP (Sep. 29, 2014) — Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com
Dr.'s Unsure of Cause of Fast-Spreading Virus

Dr.'s Unsure of Cause of Fast-Spreading Virus

AP (Sep. 29, 2014) — Doctors at the Children's Hospital of Colorado say they have treated over 4,000 children with serious respiratory illnesses since August. Nine of the patients have shown distinct neurological symptoms, including limb weakness. (Sept. 29) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins