Featured Research

from universities, journals, and other organizations

Shockwaves work better than surgery for smaller kidney stones trapped in the ureter, study suggests

Date:
November 19, 2010
Source:
Wiley-Blackwell
Summary:
Surgeons are recommending two different techniques for removing single kidney stones that have become lodged in the ureter, based on results from 273 patients. Noninvasive shockwaves worked best for stones of up to 1 cm, while larger stones were more effectively removed using a ureteroscope.

Different techniques should be used to remove single stones that have become lodged in the distal ureter after being expelled by the kidney, depending on whether they are under or above one centimetre, according to the December issue of BJUI.

Surgeons from the Department of Urology at University Federico II, Naples, Italy, believe that extracorporeal shockwave lithotripsy (ESWL) -- which uses a non-invasive acoustic pulse to break down ureteric stones -- should be the treatment of first choice in patients with a stone of up to 1cm. Patients with a stone over 1cm should be treated using uretoscopy (URS), where a ureteroscope is passed into the distal ureter to remove the stone.

"ESWL and URS are both accepted treatments for distal ureteric stones, but there is a lot of discussion about which surgical technique should be used as a first-line strategy for this condition" explains co-author Professor Vincenzo Mirone.

"Approximately one in three adults with kidney stones will have a distal ureteric stone at some point in their lives. Most stones with a diameter of up to 0.5cm will be expelled spontaneously when the patient urinates without requiring any active intervention. For larger stones that get stuck in the ureter, spontaneous expulsion is very difficult and requires active intervention."

The Italian team studied 273 patients with single distal ureteric stones ranging from 0.5cm to 1.5cm, in what they believe is the first prospective randomised study comparing ESWL using an electromagnetic lithotripter and URS.

There were no significant differences between the groups, which had an average age of 50 and were equally split between males and females.

Most of the ESWL treatments (98%) were performed on an outpatient basis and none of the patients required anaesthesia or sedation. Patients received 120 shockwaves, with an average of 3,200 per session. Treatment sessions ranged from 29 to 42 minutes, averaging just under 34 minutes.

The majority of the URS treatments (96%) were performed on an inpatient basis, with 22% of patients receiving general anaesthesia, 66% receiving local anaesthesia and 12% just receiving sedation. Surgery time ranged from 22 to 52 minutes, averaging just under 34 minutes.

Overall results included:

  • Just under 93% of the ESWL patients achieved stone-free status after the procedure, with the remaining seven per cent successfully treated using URS. One ESWL session was sufficient in 55% of cases, two sessions were needed in 31% and three in 13%.
  • Fifteen per cent (21) of the ESWL patients suffered complications, with two-thirds requiring a ureteric stent following obstructive pyelonephritis (kidney infection) and just under half reporting mild pain.
  • Just under 95% of the URS patients were stone free following their procedure, 92% after the first procedure and the remainder after four weeks following a second URS procedure.
  • Nineteen per cent (26) of the URS patients suffered complications. Nine patients had intraoperative complications, 15 had postoperative fever and seven had postoperative bleeding.

    "Statistical analysis showed no significant differences in overall stone free rates, treatment duration, complications and the need for auxiliary procedures" says Professor Mirone.

    "However, there were clear differences in both groups when we divided them into patients with stones of up to 1cm and stones of over 1cm."

  • ESWL patients with stones of 1cm or less had significantly fewer complications than patients with stones of more than 1cm. (7% versus 28%). They also required significantly fewer re-treatments (12% versus 80%) and auxiliary procedures (3% versus 20%). Stone-free status also fell from 96% for smaller stones to 90% for larger stones.
  • Stone-free rates in URS patients were very similar, regardless of stone size, at approximately 95%. Retreatment was higher in patients with stones exceeding 1cm (11% versus 5%) but complications were lower (14% versus 24%) as was the need for auxiliary procedures (12% versus 25%).

"These results clearly indicate that ESWL should be the first choice for patients with stones of 1cm and under and URS should be the first choice for patients with stones exceeding 1cm" concludes Professor Mirone.


Story Source:

The above story is based on materials provided by Wiley-Blackwell. Note: Materials may be edited for content and length.


Journal Reference:

  1. Paolo Verze, Ciro Imbimbo, Gennaro Cancelmo, Massimiliano Creta, Alessandro Palmieri, Francesco Mangiapia, Roberto Buonopane, Vincenzo Mirone. Extracorporeal shockwave lithotripsy vs ureteroscopy as first-line therapy for patients with single, distal ureteric stones: a prospective randomized study. BJU International, 2010; 106 (11): 1748 DOI: 10.1111/j.1464-410X.2010.09338.x

Cite This Page:

Wiley-Blackwell. "Shockwaves work better than surgery for smaller kidney stones trapped in the ureter, study suggests." ScienceDaily. ScienceDaily, 19 November 2010. <www.sciencedaily.com/releases/2010/11/101118110757.htm>.
Wiley-Blackwell. (2010, November 19). Shockwaves work better than surgery for smaller kidney stones trapped in the ureter, study suggests. ScienceDaily. Retrieved August 28, 2014 from www.sciencedaily.com/releases/2010/11/101118110757.htm
Wiley-Blackwell. "Shockwaves work better than surgery for smaller kidney stones trapped in the ureter, study suggests." ScienceDaily. www.sciencedaily.com/releases/2010/11/101118110757.htm (accessed August 28, 2014).

Share This




More Health & Medicine News

Thursday, August 28, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Mini Pacemaker Has No Wires

Mini Pacemaker Has No Wires

Ivanhoe (Aug. 27, 2014) Cardiac experts are testing a new experimental device designed to eliminate major surgery and still keep the heart on track. Video provided by Ivanhoe
Powered by NewsLook.com
After Cancer: Rebuilding Breasts With Fat

After Cancer: Rebuilding Breasts With Fat

Ivanhoe (Aug. 27, 2014) More than 269 million women are diagnosed with breast cancer each year. Many of them will need surgery and radiation, but there’s a new simple way to reconstruct tissue using a patient’s own fat. Video provided by Ivanhoe
Powered by NewsLook.com
Blood Clots in Kids

Blood Clots in Kids

Ivanhoe (Aug. 27, 2014) Every year, up to 200,000 Americans die from a blood clot that travels to their lungs. You’ve heard about clots in adults, but new research shows kids can get them too. Video provided by Ivanhoe
Powered by NewsLook.com
Radio Waves Knock out Knee Pain

Radio Waves Knock out Knee Pain

Ivanhoe (Aug. 27, 2014) Doctors have used radio frequency ablation or RFA to reduce neck and back pain for years. But now, that same technique is providing longer-term relief for patients with severe knee pain. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins