Featured Research

from universities, journals, and other organizations

'Vast majority' of acoustic tumor patients benefit from surgery, study suggests

Date:
December 7, 2010
Source:
Loyola University Health System
Summary:
Surgery to remove tumors under the brain known as acoustic neuromas produces favorable outcomes in the "vast majority" of patients, according to one of the largest studies of its kind.

Surgery to remove tumors under the brain known as acoustic neuromas produces favorable outcomes in the "vast majority" of patients, according to one of the largest studies of its kind.

Related Articles


Loyola University Hospital surgeons Dr. Douglas Anderson and Dr. John Leonetti followed 730 patients whom they had jointly operated on during a 21-year period. Patients ranged in age from 9 to 79, with a median age of 48. The average clinical follow-up was 32 months.

Every patient survived the surgery, and the surgeons were able to completely remove the tumors in 95.1 percent of the patients. Ninety percent of patients experienced little or no facial paralysis. And among those who still retained hearing in the affected ear before surgery, 44 percent came out of the surgery with useful hearing in that ear, and 63 percent had at least some hearing.

These results are as good as or better than any other series of acoustic neuromas reported in the medical literature.

"With careful microsurgical technique, one can achieve gross total resection [removal] of the vast majority of acoustic tumors with minimal major morbidity or mortality and at the same time achieve a high percentage of normal to near-normal facial function," the study authors concluded.

Anderson is first author of the study. He presented results at the 2010 Congress of Neurological Surgeons, which awarded him the Synthes Skull Base Surgery Award.

An acoustic neuroma, also known as a vestibular schwannoma, is a slow-growing, usually benign, tumor, located behind the ear on the nerve that connects the ear to the brain. The tumor can cause hearing loss in one ear and paralysis on one side of the face. If the tumor grows large enough, it can be fatal. Treatment options include microsurgery (surgery with a microscope), radiation or simply keeping a watchful eye on the tumor.

In the study, the average tumor diameter was 2.2 cm, and 89.5 percent of patients had experienced partial or complete loss of hearing in one ear. Other presurgery symptoms included tinnitus (43.7 percent of patients), dizziness/imbalance (26.8 percent), facial numbness (11.1 percent), headache (10.3 percent) and facial weakness (2.6 percent).

Leonetti and Anderson work as a team, with Leonetti gaining access to the tumor and Anderson removing it. If the patient still retains hearing, Leonetti uses one of two surgical techniques, called the retrosigmoid approach or the middle fossa approach. If the patient has lost all hearing, Leonetti uses a technique called the translabyrinthine approach. Leonetti is a professor in the departments of Otolaryngology and Neurological Surgery and program director of Cranial Base Surgery, and Anderson is a professor in the Department of Neurological Surgery at Loyola University Chicago Stritch School of Medicine.

In recent years, the adoption of techniques to monitor neural structures during surgery has enabled surgeons to frequently preserve hearing and facial nerves. "Before, the goal simply was to get the tumor out and be glad if the patient survived," Anderson said.

Though Anderson and Leonetti have their own practices, they also collaborate to remove acoustic neuromas and other tumors. Over the last 23 years, they have performed about 1,250 surgeries together.

"It's been a long and successful partnership," Anderson said. "We have had wonderful results. It's like a nice marriage."

Anderson said Leonetti "is a very innovative surgeon, and extremely adept at the myriad of approaches to the skull base. He also has a wonderful attitude -- highly professional but also fun to work with."

Leonetti also has high praise for Anderson. "He is the most technically gifted neurosurgeon I have ever seen," Leonetti said. "More importantly, he is a kind, compassionate and wonderful person, but he'll never beat me at golf."

Other co-authors of the study are Dr. Edward Perry, a resident in neurological surgery and Marc Pisansky, a research assistant.


Story Source:

The above story is based on materials provided by Loyola University Health System. Note: Materials may be edited for content and length.


Cite This Page:

Loyola University Health System. "'Vast majority' of acoustic tumor patients benefit from surgery, study suggests." ScienceDaily. ScienceDaily, 7 December 2010. <www.sciencedaily.com/releases/2010/12/101207121433.htm>.
Loyola University Health System. (2010, December 7). 'Vast majority' of acoustic tumor patients benefit from surgery, study suggests. ScienceDaily. Retrieved November 22, 2014 from www.sciencedaily.com/releases/2010/12/101207121433.htm
Loyola University Health System. "'Vast majority' of acoustic tumor patients benefit from surgery, study suggests." ScienceDaily. www.sciencedaily.com/releases/2010/12/101207121433.htm (accessed November 22, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, November 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com
Milestone Birthdays Can Bring Existential Crisis, Study Says

Milestone Birthdays Can Bring Existential Crisis, Study Says

Newsy (Nov. 21, 2014) Researchers find that as people approach new decades in their lives they make bigger life decisions. Video provided by Newsy
Powered by NewsLook.com
Ebola: Life Without School in Guinea

Ebola: Life Without School in Guinea

AFP (Nov. 21, 2014) Following the closure of schools and universities in Guinea because of the Ebola virus, students look for temporary work or gather in makeshift classrooms to catch up on their syllabus. Duration: 02:14 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins