Featured Research

from universities, journals, and other organizations

Novel memory-enhancing mechanism in brain

Date:
December 15, 2010
Source:
University of California - Irvine
Summary:
Researchers have identified a novel mechanism in the brain that boosts memory. Scientists found that a small protein called neuropeptide S can strengthen and prolong memories of everything from negative events to simple objects.

UC Irvine researchers have identified a novel mechanism in the brain that boosts memory.

In collaboration with scientists at Germany's University of Munster, the UCI team found that a small protein called neuropeptide S can strengthen and prolong memories of everything from negative events to simple objects.

According to study leader Rainer Reinscheid, UCI associate professor of pharmaceutical sciences, the discovery could provide important clues about how the brain stores memories and also lead to new treatments for Alzheimer's disease, dementia and other cognitive impairments.

"Additionally, it may help us better understand post-traumatic stress disorder, which involves exaggerated memories of traumatic events," he said.

In tests on mice, the researchers observed that if neuropeptide S receptors in the brain were activated immediately after a learning experience, it could be recalled for much longer and with much greater intensity.

This memory enhancement lasted up to a week, Reinscheid said, but when NPS receptor activation was disrupted, the mice didn't remember events as strongly -- if at all -- when tested just a day or two later.

Study results, which appear in a Dec. 8 advance online article for the journal Neuropsychopharmacology, are in accordance with Reinscheid's previous findings that NPS causes wakefulness and has a calming effect.

"It appears that the combination of increased alertness and reduced anxiety produced by NPS prepares the animals to learn much better," he said. "Memory is remarkably improved after activation of their NPS system, and the effects are long-lasting, independent of content."

Naoe Okamura, Celia Garau, Dee Duangdao and Stewart Clark of UCI as well as Kay Jungling and Hans-Christian Pape of the University of Munster contributed to the study, which was funded in part by the National Institute of Mental Health.


Story Source:

The above story is based on materials provided by University of California - Irvine. Note: Materials may be edited for content and length.


Journal Reference:

  1. Naoe Okamura, Celia Garau, Dee M Duangdao, Stewart D Clark, Kay Jόngling, Hans-Christian Pape, Rainer K Reinscheid. Neuropeptide S Enhances Memory During the Consolidation Phase and Interacts with Noradrenergic Systems in the Brain. Neuropsychopharmacology, 2010; DOI: 10.1038/npp.2010.207

Cite This Page:

University of California - Irvine. "Novel memory-enhancing mechanism in brain." ScienceDaily. ScienceDaily, 15 December 2010. <www.sciencedaily.com/releases/2010/12/101214122852.htm>.
University of California - Irvine. (2010, December 15). Novel memory-enhancing mechanism in brain. ScienceDaily. Retrieved July 25, 2014 from www.sciencedaily.com/releases/2010/12/101214122852.htm
University of California - Irvine. "Novel memory-enhancing mechanism in brain." ScienceDaily. www.sciencedaily.com/releases/2010/12/101214122852.htm (accessed July 25, 2014).

Share This




More Mind & Brain News

Friday, July 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

University Quiz Implies Atheists Are Smarter Than Christians

University Quiz Implies Atheists Are Smarter Than Christians

Newsy (July 25, 2014) — An online quiz from a required course at Ohio State is making waves for suggesting atheists are inherently smarter than Christians. Video provided by Newsy
Powered by NewsLook.com
Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

Beatings and Addiction: Pakistan Drug 'clinic' Tortures Patients

AFP (July 24, 2014) — A so-called drugs rehab 'clinic' is closed down in Pakistan after police find scores of ‘patients’ chained up alleging serial abuse. Duration 03:05 Video provided by AFP
Powered by NewsLook.com
New Painkiller Designed To Discourage Abuse: Will It Work?

New Painkiller Designed To Discourage Abuse: Will It Work?

Newsy (July 24, 2014) — The FDA approved Targiniq ER on Wednesday, a painkiller designed to keep users from abusing it. Like any new medication, however, it has doubters. Video provided by Newsy
Powered by NewsLook.com
Can Watching TV Make You Feel Like A Failure?

Can Watching TV Make You Feel Like A Failure?

Newsy (July 24, 2014) — A study by German researchers claims watching TV while you're stressed out can make you feel guilty and like a failure. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins