Featured Research

from universities, journals, and other organizations

Surgery sooner rather than later better for children with perforated appendicitis

Date:
February 22, 2011
Source:
JAMA and Archives Journals
Summary:
For children with a perforated appendix, early appendectomy appears to reduce the time away from normal activities and has fewer adverse events as compared to another common option, the interval appendectomy, which is performed several weeks after diagnosis, according to a new study.

For children with a perforated appendix, early appendectomy appears to reduce the time away from normal activities and has fewer adverse events as compared to another common option, the interval appendectomy, which is performed several weeks after diagnosis, according to a report published online first in the Archives of Surgery, one of the JAMA/Archives journals. The paper will appear in the June 2011 print issue of the journal.

"Appendicitis is the most common gastrointestinal condition that requires urgent surgical treatment in children in the United States," according to background information provided by the authors. About 30 percent of the cases are perforated appendicitis. For acute, nonperforated appendicitis, the universally accepted treatment is urgent appendectomy. But, for children with perforated appendicitis, there are two commonly used surgical treatment options: early appendectomy, in which the patient undergoes surgery within the first 24 hours of hospitalization, and interval appendectomy, in which the surgical removal of the appendix is planned for 6 to 8 weeks after the initial diagnosis and the patient has left the hospital and returned to normal activities. The authors note the potential advantage of the interval appendectomy is to perform the operation when contamination in the abdominal cavity has resolved, potentially resulting in fewer surgical complications.

To compare the effectiveness and adverse event rates of early versus interval appendectomy, Martin L. Blakely, M.D., M.S., from University of Tennessee Health Science Center, Memphis, Tenn., and colleagues evaluated the surgical outcomes of 131 patients under the age of 18 who had a preoperative diagnosis of perforated appendicitis between October 2006 and August 2009. The patients were randomized into two groups: 64 were in the early appendectomy group and 67 were in the interval appendectomy group. The researchers used time away from normal activities and overall adverse event rates (such as, intra-abdominal abscess, surgical site infection, unplanned readmission) as the main outcome measures.

"Early appendectomy, compared with interval appendectomy, significantly reduced the time away from normal activities (average, 13.8 vs. 19.4 days)," the authors report. The overall adverse event rate was 30 percent compared to 55 percent for early versus interval appendectomy. The total length of hospital stay was also reduced by an average of more than two days for patients receiving the early appendectomy compared to those who received the interval appendectomy. Some of the patients in the interval group (23 patients or 34 percent) had an appendectomy earlier than planned because of failure to improve (17 patients), recurrent appendicitis (five patients), and other reasons (one patient).

"We found that those treated with early appendectomy return to normal activities an average of five days earlier. Because a child's time away from normal activities limits parents' abilities to work, we believe it is an important outcome from a patient and family perspective," the authors remark. "The overall adverse event rate after early appendectomy was significantly lower compared with interval appendectomy," the authors conclude.


Story Source:

The above story is based on materials provided by JAMA and Archives Journals. Note: Materials may be edited for content and length.


Journal Reference:

  1. Martin L. Blakely; Regan Williams; Melvin S. Dassinger; James W. Eubanks, III; Peter Fischer; Eunice Y. Huang; Elizabeth Paton; Barbara Culbreath; Allison Hester; Christian Streck; S. Douglas Hixson; Max R. Langham, Jr. Early vs Interval Appendectomy for Children With Perforated Appendicitis. Archives of Surgery, 2011; DOI: 10.1001/archsurg.2011.6

Cite This Page:

JAMA and Archives Journals. "Surgery sooner rather than later better for children with perforated appendicitis." ScienceDaily. ScienceDaily, 22 February 2011. <www.sciencedaily.com/releases/2011/02/110221163056.htm>.
JAMA and Archives Journals. (2011, February 22). Surgery sooner rather than later better for children with perforated appendicitis. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/2011/02/110221163056.htm
JAMA and Archives Journals. "Surgery sooner rather than later better for children with perforated appendicitis." ScienceDaily. www.sciencedaily.com/releases/2011/02/110221163056.htm (accessed April 20, 2014).

Share This



More Health & Medicine News

Sunday, April 20, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Nine-Month-Old Baby Can't Open His Mouth

Nine-Month-Old Baby Can't Open His Mouth

Newsy (Apr. 19, 2014) Nine-month-old Wyatt Scott was born with a rare disorder called congenital trismus, which prevents him from opening his mouth. Video provided by Newsy
Powered by NewsLook.com
'Holy Grail' Of Weight Loss? New Find Could Be It

'Holy Grail' Of Weight Loss? New Find Could Be It

Newsy (Apr. 18, 2014) In a potential breakthrough for future obesity treatments, scientists have used MRI scans to pinpoint brown fat in a living adult for the first time. Video provided by Newsy
Powered by NewsLook.com
Little Progress Made In Fighting Food Poisoning, CDC Says

Little Progress Made In Fighting Food Poisoning, CDC Says

Newsy (Apr. 18, 2014) A new report shows rates of two foodborne infections increased in the U.S. in recent years, while salmonella actually dropped 9 percent. Video provided by Newsy
Powered by NewsLook.com
Scientists Create Stem Cells From Adult Skin Cells

Scientists Create Stem Cells From Adult Skin Cells

Newsy (Apr. 17, 2014) The breakthrough could mean a cure for some serious diseases and even the possibility of human cloning, but it's all still a way off. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins