Featured Research

from universities, journals, and other organizations

Radiation at time of lumpectomy may offer faster, more precise treatment for breast cancer patients, experts say

Date:
April 13, 2011
Source:
Northwestern Memorial Hospital
Summary:
Physicians are currently utilizing a new treatment option for breast cancer that allows women to receive a full dose of radiation therapy during breast conserving surgery. Traditionally, women who opt to have a lumpectomy must first have surgery then undergo approximately six weeks of radiation. This schedule can be challenging for women who have busy schedules or do not have access to a center offering radiation therapy. In some cases, the demanding schedule causes women to not comply with the recommended course of treatment, increasing their risk for cancer recurrence.

Northwestern Medicine physicians are currently utilizing a new treatment option for breast cancer that allows women to receive a full dose of radiation therapy during breast conserving surgery. Traditionally, women who opt to have a lumpectomy must first have surgery then undergo approximately six weeks of radiation. This schedule can be challenging for women who have busy schedules or do not have access to a center offering radiation therapy. In some cases, the demanding schedule causes women to not comply with the recommended course of treatment, increasing their risk for cancer recurrence. Intraoperative radiation therapy combines lumpectomy and the full course of radiation during a two and half hour operation.

Related Articles


"With this technique, the radiation oncologist will be in the operating room administering radiation to the tumor bed immediately following the surgeon's removal of the tumor," said William Small, Jr., MD, vice chairman radiation oncology at Northwestern Memorial Hospital and professor of radiation oncology at Northwestern University Feinberg School of Medicine. "Instead of waiting a month to start the radiation therapy, it will take place immediately. A patient will wake up from surgery and have received the full amount of radiation therapy that is typically administered over six weeks."

Currently, a breast cancer patient first sees a surgeon to remove the tumor and then is referred to a radiation oncologist for follow up radiotherapy. Intraoperative radiation therapy allows physicians to deliver radiotherapy at the time of surgery directly to the area where the cancer was removed. Using a system called IntraBeam®, the radiation oncologist is now able to be in the operating room with the surgical oncologist, delivering the entire dose of radiation during surgery. A large international randomized trial confirmed that delivering radiation at the time of lumpectomy was as effective in preventing breast cancer recurrence as whole breast radiation therapy in selected patients (WBRT).

Not all patients who choose lumpectomy comply with the recommended follow up treatment because of factors including time, money, distance and access to a treatment facility. Neglecting follow up radiation after lumpectomy can increase the risk of cancer recurrence. Intraoperative radiation significantly cuts treatment time and allows women to complete radiation and surgery at the same time.

"By eliminating the geographic and time constraints of traditional radiotherapy, intraoperative radiation can make breast conservation surgery a realistic option for more women," said Kevin Bethke, MD, surgical oncologist at Northwestern Memorial and assistant professor of clinical surgery at the Feinberg School. "Active women with busy jobs can choose lumpectomy and comply with the recommended radiation therapy, but limit the impact the treatment has on their lives."

Along with offering an expedited treatment schedule, intraoperative radiation therapy also has the potential for better cosmetic outcomes, including less scarring, and fewer side effects compared to those associated with WBRT. Skin reactions, including redness, rashes, and irritation, as well as more severe complications including fatigue, swelling, tissue stiffness and scarring are sometimes associated with traditional radiation therapy.

While initial findings indicate single-dose radiation is as effective as WBRT in limiting recurrence of breast cancer in selected patients, it is not an option for every breast cancer diagnosis. Currently, only women with early stage breast cancer are considered as candidates for intraoperative radiation therapy.

"This isn't a replacement for traditional breast cancer treatment, but for the right candidate it may be an attractive alternative," said Small. "This has potential to expand access to radiation therapy allowing more women to comply with the recommended course of treatment. Hopefully, with a more concise and convenient treatment available, a broader group of women will have the option to choose breast conserving treatment options."

The physicians hope that by offering intraoperative radiation therapy, they can help their patients effectively treat their cancer, but also do so in a manner that minimizes its impact on their daily lives. "A cancer diagnosis can be extremely stressful for a patient, so it's important that treatment is not," said Bethke. "With this new option, we're giving women a way to treat their disease while continuing to live a normal, active life."


Story Source:

The above story is based on materials provided by Northwestern Memorial Hospital. Note: Materials may be edited for content and length.


Cite This Page:

Northwestern Memorial Hospital. "Radiation at time of lumpectomy may offer faster, more precise treatment for breast cancer patients, experts say." ScienceDaily. ScienceDaily, 13 April 2011. <www.sciencedaily.com/releases/2011/04/110412121316.htm>.
Northwestern Memorial Hospital. (2011, April 13). Radiation at time of lumpectomy may offer faster, more precise treatment for breast cancer patients, experts say. ScienceDaily. Retrieved November 25, 2014 from www.sciencedaily.com/releases/2011/04/110412121316.htm
Northwestern Memorial Hospital. "Radiation at time of lumpectomy may offer faster, more precise treatment for breast cancer patients, experts say." ScienceDaily. www.sciencedaily.com/releases/2011/04/110412121316.htm (accessed November 25, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Tuesday, November 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) — The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) — Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) — Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) — A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins