Featured Research

from universities, journals, and other organizations

High risks associated with egg donation to women with Turner’s syndrome, research reveals

Date:
May 4, 2011
Source:
European Society of Endocrinology
Summary:
Pregnancy via egg donation for women with Turner’s syndrome is potentially risky, both for the mother and the child, according to a multi-center study.

Pregnancy via egg donation for women with Turner's syndrome is potentially risky, both for the mother and the child, according to a multi-centre study presented at the European Congress of Endocrinology in Rotterdam.

Related Articles


Turner's syndrome is a chromosomal disorder which affects approximately 1 in 2500 women. Most women are born with two X chromosomes, but a woman with Turner's syndrome has only a single X chromosome, which leads to a variety of health problems. These include a greater tendency to heart disease, skeletal problems, and short stature (which is often treated with growth hormone). In addition, women who grow up with Turner's syndrome are normally infertile.

Some women with Turner's syndrome have been able to bear children by receiving donated eggs (oocyte donation), leading to the possibility that they will be able to raise a family. However, new work led by researchers from the University of Nice in France now shows that this is a high-risk option.

Professor Patrick Fénichel led a multi-centre study which looked at the results of Turner pregnancies in almost all the French centres for assisted reproduction carrying out egg donation. They followed the pregnancies of 93 mothers who had Turner's syndrome. They found that in 37.8% of pregnancies, mothers suffered from pregnancy-associated hypertensive disorders; these included preeclampsia in 54.8% of cases, and severe eclampsia in four patients. In the babies of Turner's mothers, 38.3% were born premature and 27.5% of the babies suffered from in-utero growth retardation. Two mothers died from rupture of the aorta after giving birth by caesarean section, and a fetal death was linked to eclampsia in the mother. Only 40% of pregnancies were associated with a normal outcome for both the mother and child.

Researcher Professor Patrick Fénichel commented:

"Most women with Turner's syndrome are infertile. If you can't have a baby it can be very distressing, and donated eggs can give these women a chance of raising a family. However, this work shows that for women who have Turner's syndrome, pregnancy is a high-risk option, both for the mother and the baby. The mothers have a significantly increased risk of illness and even death by aortic dissection and eclampsia, but in addition the fetus is also at risk of problems, such as growth problems following pre-eclampsia, and stress. Only 40% of the pregnancies we studied produced an absolutely normal outcome for both mother and baby.

"In these circumstances, we need to be very cautious indeed about recommending mothers to undergo egg donation. It is important that women with Turner's syndrome who undergo egg donation have their cardiac function monitored before, during and after pregnancy, and that they are very closely monitored by their physician throughout and after pregnancy."

Professor Fénichel went on to state, "My group and the French oocyte donation research group will now concentrate on understanding if eclampsia is linked only to Turner's syndrome or also to egg donation itself. We will also look at ways in which better monitoring during pregnancy, delivery and the immediate post-partum period in an appropriate hospital centre might improve the outcomes of pregnancy in Turner's mothers."


Story Source:

The above story is based on materials provided by European Society of Endocrinology. Note: Materials may be edited for content and length.


Cite This Page:

European Society of Endocrinology. "High risks associated with egg donation to women with Turner’s syndrome, research reveals." ScienceDaily. ScienceDaily, 4 May 2011. <www.sciencedaily.com/releases/2011/05/110503181018.htm>.
European Society of Endocrinology. (2011, May 4). High risks associated with egg donation to women with Turner’s syndrome, research reveals. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2011/05/110503181018.htm
European Society of Endocrinology. "High risks associated with egg donation to women with Turner’s syndrome, research reveals." ScienceDaily. www.sciencedaily.com/releases/2011/05/110503181018.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) — The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) — Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) — Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com
Are Female Bosses More Likely To Be Depressed?

Are Female Bosses More Likely To Be Depressed?

Newsy (Nov. 24, 2014) — A new study links greater authority with increased depressive symptoms among women in the workplace. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins