Featured Research

from universities, journals, and other organizations

Contraceptive pill and HRT may protect against cerebral aneurysm, study suggests

Date:
May 5, 2011
Source:
BMJ-British Medical Journal
Summary:
Women who develop cerebral aneurysms are less likely to have taken the oral contraceptive pill or hormone replacement therapy, suggesting taking estrogen could have a protective effect, reveals new research.

Women who develop cerebral aneurysms are less likely to have taken the oral contraceptive pill or hormone replacement therapy, suggesting taking estrogen could have a protective effect, reveals research published in the Journal of NeuroInterventional Surgery.

Cerebral aneurysms, weaknesses in the blood vessel walls of the brain which cause the vessels to balloon, occur more frequently in women, and it has been suggested that female hormones may play a role in their development. If the cerebral aneurysm ruptures, because the ballooning wall bursts, this can be life threatening and is known as a hemorrhagic stroke.

Estrogen helps maintain the structure of blood vessel walls by promoting the division of endothelial cells within the vessel walls, which is important for repair if the vessels become damaged. However, estrogen levels drop significantly at the menopause.

Women have been shown to be more likely to develop a cerebral aneurysms after the age of 40 years, and aneurysms are most likely to rupture between the ages of 50 and 59 years.

The authors asked 60 women with cerebral aneurysms about their use of the oral contraceptive pill and hormone replacement therapy, and this was compared with usage in 4,682 other women drawn from the general public.

Women with cerebral aneurysms were found to have been significantly less likely to have taken oral contraceptives or hormone replacement therapy. Women with cerebral aneurysms also had an earlier average age of menopause.

Previous studies have shown that use of the oral contraceptive pill protects against hemorrhagic stroke in later life, while women who start their periods early and/or do not have children are at greater risk.

Current medical management of unruptured cerebral aneurysms is limited and consists mainly of smoking cessation and blood pressure control. The alternative is a surgical intervention, such as the insertion of a coil or placement of a clip, to try to control the aneurysm, and a lifetime of anxiety.

The authors say that the results of this study may not only provide additional insight into how cerebral aneurysms develop and progress, but more importantly may lead to new therapies for patients, either harboring an unruptured cerebral aneurysm or at risk of developing one, that address their underlying vascular predisposition towards aneurysms.


Story Source:

The above story is based on materials provided by BMJ-British Medical Journal. Note: Materials may be edited for content and length.


Cite This Page:

BMJ-British Medical Journal. "Contraceptive pill and HRT may protect against cerebral aneurysm, study suggests." ScienceDaily. ScienceDaily, 5 May 2011. <www.sciencedaily.com/releases/2011/05/110504201757.htm>.
BMJ-British Medical Journal. (2011, May 5). Contraceptive pill and HRT may protect against cerebral aneurysm, study suggests. ScienceDaily. Retrieved August 23, 2014 from www.sciencedaily.com/releases/2011/05/110504201757.htm
BMJ-British Medical Journal. "Contraceptive pill and HRT may protect against cerebral aneurysm, study suggests." ScienceDaily. www.sciencedaily.com/releases/2011/05/110504201757.htm (accessed August 23, 2014).

Share This




More Health & Medicine News

Saturday, August 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Two US Ebola Patients Leave Hospital Free of the Disease

Two US Ebola Patients Leave Hospital Free of the Disease

AFP (Aug. 21, 2014) Two American missionaries who were sickened with Ebola while working in Liberia and were treated with an experimental drug are doing better and have left the hospital, doctors say on August 21, 2014. Duration: 01:05 Video provided by AFP
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins