Featured Research

from universities, journals, and other organizations

Researcher identifies nearly 100 studies supporting use of thermal ablation to treat lung cancer

Date:
August 31, 2011
Source:
Lifespan
Summary:
New research supports the use of ablation procedures for the treatment of lung cancer.

The journal Radiology will publish in its September issue an article written by Damian E. Dupuy, M.D., director of tumor ablation at Rhode Island Hospital, supporting the use of ablation procedures for the treatment of lung cancer. The article, "Image-guided Thermal Ablation of Lung Malignancies," reviews the results of nearly 100 studies conducted between 1991 and 2011 that conclude that image-guided ablation for lung cancer is a successful alternative for patients who cannot withstand surgery due to advanced age or medical comorbidities.

Percutaneous image-guided tumor ablation, which has been applied to a variety of solid tumors, is a proven alternative to radiation therapy and surgery. It is being adopted by many in the radiology community, and has begun to take hold with physicians in the surgical, medical, and radiation oncology fields who are incorporating this new treatment in the care of their patients.

"Many of the lung cancer patients we see at Rhode Island Hospital are unable to have surgery, and may have trouble tolerating radiation therapy," Dupuy said. "Treating these patients with thermal ablation provides them with a safe, effective alternative. It also allows them to receive treatment on an outpatient basis, and enables them get back to their lives more quickly."

Image-guided ablation is proving to be an important tool in the treatment of primary and secondary lung tumors. It offers clinicians and patients a repeatable, effective, low-cost, and safe treatment and, in some cases, cure of both primary and metastatic thoracic malignancies either before or concurrently with systemic therapy and radiation therapy.

Radiofrequency ablation is the current ablative method of choice, although other techniques, including microwave ablation, laser ablation, and cryoablation, are also available. Each of these image-guided thermal ablation procedures involves the use of needlelike applicators that are placed directly into tumors by using imaging guidance. Tumors are destroyed by the application of either intense heat or cold.

Dupuy reviewed the findings of lung ablation studies conducted between 1991 and 2011, including 16 in which he was an investigator. He served as the senior author on the majority of the studies, and as principal investigator on four: "Percutaneous radiofrequency ablation of malignancies in the lung," (2000); "Image-guided radiofrequency tumor ablation: challenges and opportunities -- part II," (2001); "Radiofrequency ablation followed by conventional radiotherapy for medically inoperable stage I non-small cell lung cancer," (2006); and "Radiofrequency and microwave tumor ablation in patients with implanted cardiac devices: Is it safe?" (2010).

Dupuy's review of the literature concludes that thermal ablation has achieved an overall survival rate of 48 to 80 percent at two years. Based on the numbers of published reports, and a 13 percent increase from 2007 to 2008 in the use of Medicare Current Procedural Terminology code for lung radio frequency ablation, image-guided ablation of thoracic malignancies is definitely increasing. It is clear that patients who have lung malignancies with limited treatment options are benefiting from image-guided ablation therapy, though the exact subset of patients who will benefit most and with what ablating technology remains unknown. Therefore, additional research must be conducted.

Dupuy also said that prospective comparisons of this technology with other treatment alternatives (i.e. stereotactic body radiation therapy alone or in combination in similar populations) are necessary if this field is to garner more widespread support and use in the oncology community.


Story Source:

The above story is based on materials provided by Lifespan. Note: Materials may be edited for content and length.


Cite This Page:

Lifespan. "Researcher identifies nearly 100 studies supporting use of thermal ablation to treat lung cancer." ScienceDaily. ScienceDaily, 31 August 2011. <www.sciencedaily.com/releases/2011/08/110831115803.htm>.
Lifespan. (2011, August 31). Researcher identifies nearly 100 studies supporting use of thermal ablation to treat lung cancer. ScienceDaily. Retrieved July 31, 2014 from www.sciencedaily.com/releases/2011/08/110831115803.htm
Lifespan. "Researcher identifies nearly 100 studies supporting use of thermal ablation to treat lung cancer." ScienceDaily. www.sciencedaily.com/releases/2011/08/110831115803.htm (accessed July 31, 2014).

Share This




More Health & Medicine News

Thursday, July 31, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

House Republicans Vote to Sue Obama Over Healthcare Law

House Republicans Vote to Sue Obama Over Healthcare Law

Reuters - US Online Video (July 31, 2014) The Republican-led House of Representatives votes to sue President Obama, accusing him of overstepping his executive authority in making changes to the Affordable Care Act. Mana Rabiee reports. Video provided by Reuters
Powered by NewsLook.com
Despite Health Questions, E-Cigs Are Beneficial: Study

Despite Health Questions, E-Cigs Are Beneficial: Study

Newsy (July 31, 2014) Citing 81 previous studies, new research out of London suggests the benefits of smoking e-cigarettes instead of regular ones outweighs the risks. Video provided by Newsy
Powered by NewsLook.com
Dangerous Bacteria Kills One in Florida

Dangerous Bacteria Kills One in Florida

AP (July 31, 2014) Sarasota County, Florida health officials have issued a warning against eating raw oysters and exposing open wounds to coastal and inland waters after a dangerous bacteria killed one person and made another sick. (July 31) Video provided by AP
Powered by NewsLook.com
Health Insurers' Profits Slide

Health Insurers' Profits Slide

Reuters - Business Video Online (July 30, 2014) Obamacare-related costs were said to be behind the profit plunge at Wellpoint and Humana, but Wellpoint sees the new exchanges boosting its earnings for the full year. Fred Katayama reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins