Featured Research

from universities, journals, and other organizations

The butterfly effect in nanotech medical diagnostics

Date:
February 6, 2012
Source:
Inderscience Publishers
Summary:
Tiny metallic nanoparticles that shimmer in the light like the scales on a butterfly's wing are set to become the color-change components of a revolutionary new approach to point-of-care medical diagnostics, according to a new study.

Tiny metallic nanoparticles that shimmer in the light like the scales on a butterfly's wing are set to become the color-change components of a revolutionary new approach to point-of-care medical diagnostics, according to a study published in International Journal of Design Engineering.

Related Articles


Thomas Schalkhammer and colleagues at Attophotonics Biosciences GmbH in Austria are working with Roland Palkovits of the University of Applied Sciences, in Wiener Neustadt, to develop a nanoparticle microfluidic color device for medical diagnostics. The team has demonstrated proof of principle in the detection of interleukin-6 as an important marker of acute sepsis.

The researchers point out that point-of-care medical diagnostics is an important part of healthcare today because it provides timely information to medical staff caring for patients as well as ensuring blood transfusion safety and providing useful surveillance data for emergency public health intervention as well as long-term public health strategies. Various studies, including one from the Bill and Melinda Gates Foundation and the National Institutes of Health (NIH) have emphasized repeatedly the importance of point-of-care diagnostics. As such, researchers the world over are searching for the insights and the technology to make simple, portable, and effective diagnostic devices to meet this need.

The Austrian team has developed a novel immunoassay for gold or palladium nanoparticles that are captured via immune-reactive proteins and positioned as a thin layer just a few nanometers above a light reflective surface. The nanoparticles and the mirror form an interference system the color of which can be tuned across the visible light spectrum. A microfluidic system -- a so-called lab-on-a-chip -- takes in a sample. If the target biomolecule, the disease marker, is present it will attach to the modified nanoparticles and cause a visible color change.

The addition of a silver colloidal solution enhances the effect making the metallic color change even more apparent. The tests can be performed in the clinic in just two to three minutes and importantly avoids any medical laboratory bottlenecks and incubation times for samples. The team reports that the tests are highly accurate and sensitive to a mere half a millionth of a milligram (500 picograms) per milliliter of sample. The nanoparticle test works even if the sample is cloudy.


Story Source:

The above story is based on materials provided by Inderscience Publishers. Note: Materials may be edited for content and length.


Journal Reference:

  1. Saied Assadollahi, Roland Palkovits, Peter Pointl, Thomas Schalkhammer. Development of a nanoparticle microfluidic colour device for point-of-care diagnostics. International Journal of Design Engineering, 2011; 4 (2): 159 DOI: 10.1504/IJDE.2011.045118

Cite This Page:

Inderscience Publishers. "The butterfly effect in nanotech medical diagnostics." ScienceDaily. ScienceDaily, 6 February 2012. <www.sciencedaily.com/releases/2012/02/120206122620.htm>.
Inderscience Publishers. (2012, February 6). The butterfly effect in nanotech medical diagnostics. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2012/02/120206122620.htm
Inderscience Publishers. "The butterfly effect in nanotech medical diagnostics." ScienceDaily. www.sciencedaily.com/releases/2012/02/120206122620.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Kids Die While Under Protective Services

Kids Die While Under Protective Services

AP (Dec. 18, 2014) As part of a six-month investigation of child maltreatment deaths, the AP found that hundreds of deaths from horrific abuse and neglect could have been prevented. AP's Haven Daley reports. (Dec. 18) Video provided by AP
Powered by NewsLook.com
Dads-To-Be Also Experience Hormone Changes During Pregnancy

Dads-To-Be Also Experience Hormone Changes During Pregnancy

Newsy (Dec. 18, 2014) A study from University of Michigan researchers found that expectant fathers see a decrease in testosterone as the baby's birth draws near. Video provided by Newsy
Powered by NewsLook.com
Prenatal Exposure To Pollution Might Increase Autism Risk

Prenatal Exposure To Pollution Might Increase Autism Risk

Newsy (Dec. 18, 2014) Harvard researchers found children whose mothers were exposed to high pollution levels in the third trimester were twice as likely to develop autism. Video provided by Newsy
Powered by NewsLook.com
UN: Up to One Million Facing Hunger in Ebola-Hit Countries

UN: Up to One Million Facing Hunger in Ebola-Hit Countries

AFP (Dec. 17, 2014) Border closures, quarantines and crop losses in West African nations battling the Ebola virus could lead to as many as one million people going hungry, UN food agencies said on Wednesday. Duration: 00:52 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins