Featured Research

from universities, journals, and other organizations

Bisphenol A exposure linked to increased risk of future onset of heart disease

Date:
February 23, 2012
Source:
The Peninsula College of Medicine and Dentistry
Summary:
Bisphenol A (BPA) is a controversial chemical widely used in the plastics industry. A new study followed people over a 10-year time period and shows that healthy people with higher urine concentrations of BPA were more likely to later develop heart disease.

Bisphenol A (BPA) is a controversial chemical widely used in the plastics industry. A new study followed people over a 10-year time period and shows that healthy people with higher urine concentrations of BPA were more likely to later develop heart disease. But researchers "can't be certain that BPA itself is responsible" -- more research needed to determine whether the link is causal.

Related Articles


The study was carried out by researchers at the Peninsula College of Medicine and Dentistry, the University of Exeter and the European Centre for the Environment and Human Health, in association with the University of Cambridge. The analysis was funded by the British Heart Foundation. The paper is published online in Circulation -- a Journal of the American Heart Association.

The research team had previously identified the link between BPA and the increased risk of cardiovascular disease by using two sets of US data, which are effectively snapshots in time. The previous data showed a correlation between exposure to BPA and cardiovascular disease but it could not help researchers to predict how exposure to the chemical might affect future health.

The most recent study uses data from the European Prospective Investigation of Cancer (EPIC) in Norfolk, UK, a long term population study led by the University of Cambridge, supported by the Medical Research Council UK and Cancer Research UK. It is the first time that data has been used to establish a link between exposure to BPA and future onset of cardiovascular disease.

The study compared urine BPA measures from 758 initially healthy EPIC study respondents who later developed cardiovascular disease, and 861 respondents who remained heart disease free. The findings of the study show that those who developed heart disease tended to have higher urinary BPA concentrations at the start of the 10-year period. The extent of the effect is very difficult to estimate given that just one urine specimen from each participant was available for testing at the beginning of the 10-year follow-up.

Professor David Melzer of the Peninsula Medical School, who led the team, said: "This study strengthens the statistical link between BPA and heart disease, but we can't be certain that BPA itself is responsible. It is now important that government agencies organise drug style safety trials of BPA in humans, as much basic information about how BPA behaves in the human body is still unknown."

Professor Tamara Galloway of the University of Exeter, senior author on the paper, said: "If BPA itself is directly responsible for this increase in risk, the size of effect is difficult to estimate. However, it adds to the evidence that BPA may be an additional contributor to heart disease risk alongside the major risk factors, such as smoking, high blood pressure and high cholesterol levels."

BPA is one of the world's highest production volume chemicals. The global population is exposed to BPA primarily through packaged food and drink, but also through drinking water, dental sealants, exposure to the skin and the inhalation of household dust.


Story Source:

The above story is based on materials provided by The Peninsula College of Medicine and Dentistry. Note: Materials may be edited for content and length.


Journal Reference:

  1. david Melzer; Nicholas J. Osborne; William E. Henley; Ricardo Cipelli; Anita Young; Cathryn Money; Paul Mccormack; Robert Luben; Kay-Tee Khaw; Nicholas J. Wareham; Tamara S. Galloway. Urinary Bisphenol: A Concentration and Risk of Future Coronary Artery Disease in Apparently Healthy Men and Women. Circulation, 2012 DOI: 10.1161/%u200BCIRCULATIONAHA.111.069153

Cite This Page:

The Peninsula College of Medicine and Dentistry. "Bisphenol A exposure linked to increased risk of future onset of heart disease." ScienceDaily. ScienceDaily, 23 February 2012. <www.sciencedaily.com/releases/2012/02/120223104019.htm>.
The Peninsula College of Medicine and Dentistry. (2012, February 23). Bisphenol A exposure linked to increased risk of future onset of heart disease. ScienceDaily. Retrieved November 23, 2014 from www.sciencedaily.com/releases/2012/02/120223104019.htm
The Peninsula College of Medicine and Dentistry. "Bisphenol A exposure linked to increased risk of future onset of heart disease." ScienceDaily. www.sciencedaily.com/releases/2012/02/120223104019.htm (accessed November 23, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Sunday, November 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins