Featured Research

from universities, journals, and other organizations

Facts in scientific drug literature may not be

Date:
May 29, 2012
Source:
University of Illinois at Chicago
Summary:
A growing concern with fraud and misconduct in published drug studies has led researchers to investigate the extent and reasons for retractions in the research.

A growing concern with fraud and misconduct in published drug studies has led researchers at the University of Illinois at Chicago's Center for Pharmacoeconomic Research to investigate the extent and reasons for retractions in the research.

Related Articles


"We were surprised to find the proportion of retractions due to scientific misconduct in the drug literature is higher than in general biomedical literature," said Simon Pickard, associate professor of pharmacy practice and senior author of a study published in the journal Pharmacotherapy.

Nearly three-quarters of the retracted drug studies were attributed to scientific misconduct, he said, "which includes data falsification or fabrication, questionable veracity, unethical author conduct, or plagiarism. While these studies comprise a small percentage of the overall literature, health care professionals may rely on this evidence to make treatment recommendations."

These studies can affect the treatment of thousands of patients, since scientific publications are often printed months in advance. There is an average lag in time of 39 months between the original publication and a retraction notice, Pickard said.

"Once a health care professional changes treatment options, it's not easy to reverse," said Jennifer Samp, a fellow in Pickard's research group and lead author of the study. "Staying current with new findings in scientific literature is a priority for health care practitioners -- especially pharmacists -- and it is important for them to know when a study has been retracted, especially those with manipulated data."

The UIC team found that a considerable number of the retracted papers were attributable to two authors, one based in Japan and the other in Germany.

Little attention was paid to the implications of scientific publication retractions until a 1998 review documented 235 instances from 1966 to 1997; 37 percent of the retractions were due to scientific misconduct.

Since the 1998 study, more interest has been given to retracted studies. In 2009, the Committee on Publication Ethics released the first set of guidelines to editors on issuing retractions.

"These guidelines should help to reduce the extent and impact of scientific misconduct," Pickard said. "Ironically, greater detection may give the impression that fraudulent science is on the rise, when it is actually being mitigated by these policies."

Glen Schumock, director of the UIC Center for Pharmacoeconomic Research, assisted Pickard and Samp in the study, which was funded by the UIC College of Pharmacy and Takeda Pharmaceuticals U.S.A, Inc., which funded Samp's fellowship.


Story Source:

The above story is based on materials provided by University of Illinois at Chicago. Note: Materials may be edited for content and length.


Journal Reference:

  1. Jennifer C. Samp, Glen T. Schumock, A. Simon Pickard. Retracted Publications in the Drug Literature. Pharmacotherapy, 2012 DOI: 10.1002/j.1875-9114.2012.01100.x

Cite This Page:

University of Illinois at Chicago. "Facts in scientific drug literature may not be." ScienceDaily. ScienceDaily, 29 May 2012. <www.sciencedaily.com/releases/2012/05/120529181145.htm>.
University of Illinois at Chicago. (2012, May 29). Facts in scientific drug literature may not be. ScienceDaily. Retrieved December 22, 2014 from www.sciencedaily.com/releases/2012/05/120529181145.htm
University of Illinois at Chicago. "Facts in scientific drug literature may not be." ScienceDaily. www.sciencedaily.com/releases/2012/05/120529181145.htm (accessed December 22, 2014).

Share This


More From ScienceDaily



More Science & Society News

Monday, December 22, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

After Sony Hack, What's Next?

After Sony Hack, What's Next?

Reuters - US Online Video (Dec. 19, 2014) The hacking attack on Sony Pictures has U.S. government officials weighing their response to the cyber-attack. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
S. Leone Limits Chistmas Activities to Stem Ebola Spread

S. Leone Limits Chistmas Activities to Stem Ebola Spread

AFP (Dec. 19, 2014) Sierra Leone has launched sweeping efforts to stem the spread of Ebola in the west of the country. While church services will be allowed to go ahead over the festive period, public gatherings and entertainment have been banned. Duration: 01:10 Video provided by AFP
Powered by NewsLook.com
Obama: Better Ways to Create Jobs Than Keystone Pipeline

Obama: Better Ways to Create Jobs Than Keystone Pipeline

AFP (Dec. 19, 2014) US President Barack Obama says that construction of the Keystone pipeline would have 'very little impact' on US gas prices and believes there are 'more direct ways' to create construction jobs. Duration: 00:47 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Science & Society

Business & Industry

Education & Learning

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins