Featured Research

from universities, journals, and other organizations

Older age marker may be more appropriate for papillary thyroid cancer prognosis

Date:
September 21, 2012
Source:
American Thyroid Association
Summary:
Although age 45 is used to establish staging in well-differentiated papillary thyroid cancer using the American Joint Committee on Cancer and the International Union Against Cancer TNM Classification of Malignant Tumors (TNM) staging system, a new study suggests that > 65 may be a more accurate age marker for prognosis.

Although age 45 is used to establish staging in well-differentiated papillary thyroid cancer using the American Joint Committee on Cancer and the International Union Against Cancer TNM Classification of Malignant Tumors (TNM) staging system, a new study presented at the 82nd Annual Meeting of the American Thyroid Association (ATA) in Québec City, Québec, Canada, suggests that > 65 may be a more accurate age marker for prognosis.

Related Articles


"While age at diagnosis appears to play a role in papillary thyroid cancer outcomes, new data suggest that a more appropriate age marker for prognosis is > 65 years," said Elizabeth Pearce, MD, of the Boston Medical Center and Program Co-Chair of the ATA annual meeting. "Use of this older age marker would result in down-staging of many patients, reflecting a more favorable prognosis that could avoid potentially unnecessary therapies and allay patients' fears about their longevity."

A review of the literature to determine the origin of this age marker appears to date back to an article by Byar, et al., published in European Journal of Cancer in 1979, that was underpowered and not specific to well-differentiated thyroid cancer. In addition, empiric clinical observations often suggest that patients aged 45 to 64 years appear to have similar long-term outcomes when compared to patients < 45 years of age.

A team of researchers led by Lindsay Bischoff, MD, of the Thomas Jefferson University Hospital in Philadelphia, Pa., thus conducted a study to determine the accuracy of age 45 as a prognostic cut-off. They performed a search of the Surveillance, Epidemiology, and End Result (SEER) database to obtain data for histology-confirmed papillary thyroid cancer. Data were stratified in 5-year categories by age at diagnosis from 20 to 84 years old, with patients 85 years of age and older categorized together. All stages, race/ethnicity groups, and sexes were included. A total of 53, 581 patients were identified with histologically confirmed papillary thyroid cancers.

Researchers found that the overall 5-year survival remained above 90% for all age groups under 65 years. It was not until age 65 years and older that patients had a progressively less favorable prognosis with each advancing age group.


Story Source:

The above story is based on materials provided by American Thyroid Association. Note: Materials may be edited for content and length.


Cite This Page:

American Thyroid Association. "Older age marker may be more appropriate for papillary thyroid cancer prognosis." ScienceDaily. ScienceDaily, 21 September 2012. <www.sciencedaily.com/releases/2012/09/120921123957.htm>.
American Thyroid Association. (2012, September 21). Older age marker may be more appropriate for papillary thyroid cancer prognosis. ScienceDaily. Retrieved December 19, 2014 from www.sciencedaily.com/releases/2012/09/120921123957.htm
American Thyroid Association. "Older age marker may be more appropriate for papillary thyroid cancer prognosis." ScienceDaily. www.sciencedaily.com/releases/2012/09/120921123957.htm (accessed December 19, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, December 19, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

The Best Tips to Curb Holiday Carbs

The Best Tips to Curb Holiday Carbs

Buzz60 (Dec. 19, 2014) — It's hard to resist those delicious but fattening carbs we all crave during the winter months, but there are some ways to stay satisfied without consuming the extra calories. Vanessa Freeman (@VanessaFreeTV) has the details. Video provided by Buzz60
Powered by NewsLook.com
Sierra Leone Bikers Spread the Message to Fight Ebola

Sierra Leone Bikers Spread the Message to Fight Ebola

AFP (Dec. 19, 2014) — More than 100 motorcyclists hit the road to spread awareness messages about Ebola. Nearly 7,000 people have now died from the virus, almost all of them in west Africa, according to the World Health Organization. Video provided by AFP
Powered by NewsLook.com
Researchers Test Colombian Village With High Alzheimer's Rates

Researchers Test Colombian Village With High Alzheimer's Rates

AFP (Dec. 19, 2014) — In Yarumal, a village in N. Colombia, Alzheimer's has ravaged a disproportionately large number of families. A genetic "curse" that may pave the way for research on how to treat the disease that claims a new victim every four seconds. Duration: 02:42 Video provided by AFP
Powered by NewsLook.com
Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Double-Amputee Becomes First To Move Two Prosthetic Arms With His Mind

Buzz60 (Dec. 19, 2014) — A double-amputee makes history by becoming the first person to wear and operate two prosthetic arms using only his mind. Jen Markham has the story. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins