Featured Research

from universities, journals, and other organizations

Delaying radiation therapy after hysterectomy ups risk of uterine cancer recurrence, researchers find

Date:
October 30, 2012
Source:
Henry Ford Health System
Summary:
Waiting too long after a hysterectomy to begin radiation therapy may increase the risk of uterine cancer recurrence, according to researchers.

Waiting too long after a hysterectomy to begin radiation therapy may increase the risk of uterine cancer recurrence, according to a new study from researchers at Henry Ford Hospital in Detroit.

The study shows that for patients with uterine cancer not receiving chemotherapy, tumors were more likely to return if radiation therapy was delayed nine weeks or longer following surgery, with only 43 percent having relapse-free survival after five years.

By comparison, patients starting radiation treatment soon after surgery had a five-year relapse-free survival of 90 percent.

"Our data suggests that a shorter interval of time between hysterectomy and start of radiation treatment may be beneficial for patients," says lead author Mohamed Elshaikh, M.D., senior staff physician in the Department of Radiation Oncology at Henry Ford Hospital.

Study results will be presented Tuesday, Oct. 30 at the 54th Annual Meeting of the American Society for Radiation Oncology (ASTRO) in Boston.

Endometrial cancers mainly arise from the tissue lining the uterus. They are the most common gynecologic cancers in the U.S., with more than 43,000 women diagnosed and an estimated 7,950 dying from the disease in 2010, according to the National Cancer Institute.

A total hysterectomy (surgical removal of the uterus) is the most common approach for treatment of endometrial cancers.

To assess the impact of time between hysterectomy and the start of radiation treatment on tumor recurrence, Dr. Elshaikh and his colleagues conducted a retrospective study of patients who underwent surgery for uterine cancer between 1988 and 2010.

Of the 1,450 Henry Ford patients reviewed with stage I-III uterine cancer, 308 received radiation therapy without chemotherapy after hysterectomy with at least one year follow-up. The median age for patients was 65 and the median follow-up was six years.

About 75 percent of the study group started radiation therapy less than nine weeks after surgery, while the others began treatment nine weeks or more after surgery.

Among the study group, there were 43 cases where the cancer returned. Tumor recurrence was significantly associated with treatment delay of nine weeks or longer.

Along with Dr. Elshaikh, Henry Ford study co-authors are Richard Cattaneo II, M.D.; Gordon Jacobsen, MS; and Rabbie Hanna, M.D.


Story Source:

The above story is based on materials provided by Henry Ford Health System. Note: Materials may be edited for content and length.


Cite This Page:

Henry Ford Health System. "Delaying radiation therapy after hysterectomy ups risk of uterine cancer recurrence, researchers find." ScienceDaily. ScienceDaily, 30 October 2012. <www.sciencedaily.com/releases/2012/10/121030161226.htm>.
Henry Ford Health System. (2012, October 30). Delaying radiation therapy after hysterectomy ups risk of uterine cancer recurrence, researchers find. ScienceDaily. Retrieved October 1, 2014 from www.sciencedaily.com/releases/2012/10/121030161226.htm
Henry Ford Health System. "Delaying radiation therapy after hysterectomy ups risk of uterine cancer recurrence, researchers find." ScienceDaily. www.sciencedaily.com/releases/2012/10/121030161226.htm (accessed October 1, 2014).

Share This



More Health & Medicine News

Wednesday, October 1, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pregnancy Spacing Could Have Big Impact On Autism Risks

Pregnancy Spacing Could Have Big Impact On Autism Risks

Newsy (Oct. 1, 2014) A new study says children born less than one year and more than five years after a sibling can have an increased risk for autism. Video provided by Newsy
Powered by NewsLook.com
Robotic Hair Restoration

Robotic Hair Restoration

Ivanhoe (Oct. 1, 2014) A new robotic procedure is changing the way we transplant hair. The ARTAS robot leaves no linear scarring and provides more natural results. Video provided by Ivanhoe
Powered by NewsLook.com
Insertable Cardiac Monitor

Insertable Cardiac Monitor

Ivanhoe (Oct. 1, 2014) A heart monitor the size of a paperclip that can save your life. The “Reveal Linq” allows a doctor to monitor patients with A-Fib on a continuous basis for up to 3 years! Video provided by Ivanhoe
Powered by NewsLook.com
Attacking Superbugs

Attacking Superbugs

Ivanhoe (Oct. 1, 2014) Two weapons hospitals can use to attack superbugs. Scientists in Ireland created a new gel resistant to superbugs, and a robot that can disinfect a room in minutes. Video provided by Ivanhoe
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins