Featured Research

from universities, journals, and other organizations

Earlier depression treatment prevents heart attacks, strokes, study shows

Date:
February 3, 2014
Source:
Indiana University-Purdue University Indianapolis School of Science
Summary:
New research is the first to find that treatment of depression before any apparent signs of cardiovascular disease can decrease the risk of future heart attacks and strokes by almost half.

Research led by Jesse C. Stewart, Ph.D., of the School of Science at Indiana University-Purdue University Indianapolis, is the first to find that treatment of depression before any apparent signs of cardiovascular disease can decrease the risk of future heart attacks and strokes by almost half.

"Previous studies we and others have conducted indicate that depression is a risk factor for cardiovascular disease. But past depression treatment studies involving cardiac patients have not shown the anticipated cardiovascular benefits. So we asked ourselves, what if we treated depression before the onset of cardiovascular disease? Could that cut the risk of heart attack and stroke? Our results suggest that the answer is yes," said Dr. Stewart, associate professor of psychology in the School of Science at IUPUI and affiliated scientist of the Indiana University Center for Aging Research.

The researchers followed 235 older, clinically depressed patients who were randomly assigned to standard care or to a collaborative care program involving antidepressants and psychotherapy.

Among the 168 patients with no cardiovascular disease at the start of the study, those who received collaborative care to treat their depression had a 48 percent lower risk of heart attack or stroke over the next 8 years than did patients who received standard care for their depression.

In contrast, collaborative care was not associated with a lower risk of a heart attack or stroke among the 67 patients with preexisting cardiovascular disease.

These findings suggest that depression treatment may need to be initiated before the onset of cardiovascular disease if cardiovascular benefits are desired.

The study, "Effect of Collaborative Care for Depression on Risk of Cardiovascular Events: Data from the IMPACT Randomized Controlled Trial," appears in the January 2014 issue of Psychosomatic Medicine.

"Lifestyle changes -- such as stopping smoking -- and blood pressure and cholesterol medications are important approaches to decreasing risk of heart attacks and strokes. Our findings, if confirmed in a larger clinical trial, could provide an important new approach -- depression treatment -- to preventing cardiovascular events," said Dr. Stewart.

He and his collaborators are seeking funding to conduct a larger randomized controlled trial to verify that treating depression earlier in the natural history of cardiovascular disease reduces the risk of heart attacks and strokes.

Depression affects more than 6.5 million Americans age 65 years or older, according to the National Alliance on Mental Health.

"In the near future, depression treatment may play an important role in reducing disability and death due to cardiovascular disease," said Dr. Stewart.


Story Source:

The above story is based on materials provided by Indiana University-Purdue University Indianapolis School of Science. The original article was written by Cindy Fox Aisen. Note: Materials may be edited for content and length.


Journal Reference:

  1. J. C. Stewart, A. J. Perkins, C. M. Callahan. Effect of Collaborative Care for Depression on Risk of Cardiovascular Events: Data From the IMPACT Randomized Controlled Trial. Psychosomatic Medicine, 2013; 76 (1): 29 DOI: 10.1097/PSY.0000000000000022

Cite This Page:

Indiana University-Purdue University Indianapolis School of Science. "Earlier depression treatment prevents heart attacks, strokes, study shows." ScienceDaily. ScienceDaily, 3 February 2014. <www.sciencedaily.com/releases/2014/02/140203122827.htm>.
Indiana University-Purdue University Indianapolis School of Science. (2014, February 3). Earlier depression treatment prevents heart attacks, strokes, study shows. ScienceDaily. Retrieved August 29, 2014 from www.sciencedaily.com/releases/2014/02/140203122827.htm
Indiana University-Purdue University Indianapolis School of Science. "Earlier depression treatment prevents heart attacks, strokes, study shows." ScienceDaily. www.sciencedaily.com/releases/2014/02/140203122827.htm (accessed August 29, 2014).

Share This




More Health & Medicine News

Friday, August 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com
Killer Amoeba Found in Louisiana Water System

Killer Amoeba Found in Louisiana Water System

AP (Aug. 28, 2014) State health officials say testing has confirmed the presence of a killer amoeba in a water system serving three St. John the Baptist Parish towns. (Aug. 28) Video provided by AP
Powered by NewsLook.com
Who Could Be Burnt by WHO's E-Cigs Move?

Who Could Be Burnt by WHO's E-Cigs Move?

Reuters - Business Video Online (Aug. 28, 2014) The World Health Organisation has called for the regulation of electronic cigarettes as both tobacco and medical products. Ciara Lee looks at the impact of the move on the tobacco industry. Video provided by Reuters
Powered by NewsLook.com
CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

CDC Director On Ebola Outbreak: 'It's Worse Than I Feared'

Newsy (Aug. 28, 2014) CDC director Tom Frieden says the Ebola outbreak is even worse than he feared. But he also said there's still hope to contain it. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins