Featured Research

from universities, journals, and other organizations

Secondary thyroid cancer more deadly than primary malignancy in young individuals

Date:
February 24, 2014
Source:
Wiley
Summary:
A new analysis has found that adolescents and young adults who develop thyroid cancer as a secondary cancer have a significantly greater risk of dying than those with primary thyroid cancer. The findings stress the importance of screening young cancer survivors to detect early signs of a potentially life-threatening thyroid malignancy. Thyroid cancer is one of the five most common malignancies in adolescent and young adult patients (ages 15 to 39 years). It can develop as an initial cancer or rarely after treatment for a previous cancer.

A new analysis has found that adolescents and young adults who develop thyroid cancer as a secondary cancer have a significantly greater risk of dying than those with primary thyroid cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings stress the importance of screening young cancer survivors to detect early signs of a potentially life-threatening thyroid malignancy.

Related Articles


Thyroid cancer is one of the five most common malignancies in adolescent and young adult patients (ages 15 to 39 years). It can develop as an initial cancer or rarely after treatment for a previous cancer. Melanie Goldfarb, MD, and David Freyer, DO, of the Keck School of Medicine of the University of Southern California and Children's Hospital Los Angeles, designed a study to compare the tumor characteristics, treatment, and survival of such primary versus secondary thyroid cancers in adolescent and young adult patients.

Their analysis included all adolescent and young adult thyroid cancer cases documented in the 1998-2010 American College of Surgeons National Cancer Database. Of 41,062 cases, 1349 (3.3 percent) had experienced a prior malignancy. Compared with cases of primary thyroid cancer, cases of secondary thyroid cancer were more likely to be small but to occur in more than one location. Also, patients with secondary thyroid cancer were more than 6.6-times as likely to die than patients with primary cancer, though survival with treatment is excellent for both at greater than 95%. This study suggests that there may be differences between thyroid cancers seen with or without a prior malignancy.

"This study will hopefully spur future research that will investigate if there are any causes -- biologic, environmental, prior treatment-related, or access to care disparities -- to account for the survival differences in these secondary cancers," said Dr. Goldfarb.

The authors consider whether the current screening guidelines for survivors of childhood cancer would detect these smaller cancers. Dr. Freyer noted that the results may have implications for thyroid cancer screening in young cancer survivors.


Story Source:

The above story is based on materials provided by Wiley. Note: Materials may be edited for content and length.


Journal Reference:

  1. Melanie Goldfarb and David R. Freyer. Comparison of secondary and primary thyroid cancer in adolescents and young adults. Cancer, February 2014 DOI: 10.1002/cncr.28463

Cite This Page:

Wiley. "Secondary thyroid cancer more deadly than primary malignancy in young individuals." ScienceDaily. ScienceDaily, 24 February 2014. <www.sciencedaily.com/releases/2014/02/140224081021.htm>.
Wiley. (2014, February 24). Secondary thyroid cancer more deadly than primary malignancy in young individuals. ScienceDaily. Retrieved January 31, 2015 from www.sciencedaily.com/releases/2014/02/140224081021.htm
Wiley. "Secondary thyroid cancer more deadly than primary malignancy in young individuals." ScienceDaily. www.sciencedaily.com/releases/2014/02/140224081021.htm (accessed January 31, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Saturday, January 31, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC: Get Vaccinated for Measles

CDC: Get Vaccinated for Measles

Reuters - US Online Video (Jan. 30, 2015) The CDC is urging people to get vaccinated for measles amid an outbreak that began at Disneyland and has now infected more than 90 people. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Obama To Outline New Plan For Personalized Medicine

Obama To Outline New Plan For Personalized Medicine

Newsy (Jan. 30, 2015) President Obama is expected to speak with drugmakers Friday about his Precision Medicine Initiative first introduced last week. Video provided by Newsy
Powered by NewsLook.com
NFL Concussions Down; Still on Parents' Minds

NFL Concussions Down; Still on Parents' Minds

AP (Jan. 30, 2015) The NFL announced this week that the number of game concussions dropped by a quarter over last season. Still, the dangers of the sport still weigh on players, and parents&apos; minds. (Jan. 30) Video provided by AP
Powered by NewsLook.com
U.S. Wants to Analyze DNA from 1 Million People

U.S. Wants to Analyze DNA from 1 Million People

Reuters - US Online Video (Jan. 30, 2015) The U.S. has proposed analyzing genetic information from more than 1 million American volunteers to learn how genetic variants affect health and disease. Rough Cut (no reporter narration). Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins