Featured Research

from universities, journals, and other organizations

Major depression linked with nearly twice the risk of kidney failure in diabetics

Date:
March 27, 2014
Source:
American Society of Nephrology (ASN)
Summary:
Diabetics with major depressive symptoms had an 85% higher risk of developing kidney failure, results of a new study have concluded. Minor depressive symptoms were not significantly linked with the development of kidney failure among diabetics overall.

Major depression may increase diabetes patients' risk of developing kidney failure, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). Additional studies are needed to determine whether treatment for depression can improve kidney health in patients with diabetes.

Individuals with diabetes have a high prevalence of depressive symptoms, which has previously been linked with negative health outcomes such as cardiovascular disease and premature death. Little is known about depression's associations with long-term kidney health in diabetics, however.

To investigate, Margaret Yu, MD, MS and Bessie Young, MD, MPH (VA Puget Sound Health Care System and University of Washington) and their colleagues studied 3886 adults with diabetes who were covered by a large health maintenance organization in Washington State. A total of 448 (11.5%) of the patients had major and 327 (8.4%) had minor depressive symptoms. During a median follow-up of 8.8 years, 87 patients (2.2%) developed kidney failure.

Among the major findings:

• Patients with major depressive symptoms had an 85% higher risk of developing kidney failure, after adjusting for various factors including age, sex, race/ethnicity, marital status, education, smoking, body mass index, diabetes duration, baseline kidney function, hypertension, medication use, and adherence to diabetes self-care.

• Minor depressive symptoms were not significantly linked with the development of kidney failure.

"This is the first study to show that major depressive symptoms are associated with a higher risk of kidney failure in patients with diabetes," said Dr. Yu. "As an observational cohort study, we can only identify an association between major depressive symptoms and kidney failure; additional studies are needed to determine whether treatment of depression can reduce the risk of kidney failure."

Also, because the association was not entirely explained by differences in traditional risk factors for kidney disease or diabetes self-care characteristics, more research is needed to determine the mechanisms involved.


Story Source:

The above story is based on materials provided by American Society of Nephrology (ASN). Note: Materials may be edited for content and length.


Journal Reference:

  1. M. K. Yu, N. S. Weiss, X. Ding, W. J. Katon, X.-H. Zhou, B. A. Young. Associations between Depressive Symptoms and Incident ESRD in a Diabetic Cohort. Clinical Journal of the American Society of Nephrology, 2014; DOI: 10.2215/CJN.08670813

Cite This Page:

American Society of Nephrology (ASN). "Major depression linked with nearly twice the risk of kidney failure in diabetics." ScienceDaily. ScienceDaily, 27 March 2014. <www.sciencedaily.com/releases/2014/03/140327222208.htm>.
American Society of Nephrology (ASN). (2014, March 27). Major depression linked with nearly twice the risk of kidney failure in diabetics. ScienceDaily. Retrieved July 23, 2014 from www.sciencedaily.com/releases/2014/03/140327222208.htm
American Society of Nephrology (ASN). "Major depression linked with nearly twice the risk of kidney failure in diabetics." ScienceDaily. www.sciencedaily.com/releases/2014/03/140327222208.htm (accessed July 23, 2014).

Share This




More Health & Medicine News

Wednesday, July 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Courts Conflicted Over Healthcare Law

Courts Conflicted Over Healthcare Law

AP (July 22, 2014) Two federal appeals courts issued conflicting rulings Tuesday on the legality of the federally-run healthcare exchange that operates in 36 states. (July 22) Video provided by AP
Powered by NewsLook.com
Why Do People Believe We Only Use 10 Percent Of Our Brains?

Why Do People Believe We Only Use 10 Percent Of Our Brains?

Newsy (July 22, 2014) The new sci-fi thriller "Lucy" is making people question whether we really use all our brainpower. But, as scientists have insisted for years, we do. Video provided by Newsy
Powered by NewsLook.com
Scientists Find New Way To Make Human Platelets

Scientists Find New Way To Make Human Platelets

Newsy (July 22, 2014) Boston scientists have discovered a new way to create fully functioning human platelets using a bioreactor and human stem cells. Video provided by Newsy
Powered by NewsLook.com
Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

Gilead's $1000-a-Pill Drug Could Cure Hep C in HIV-Positive People

TheStreet (July 21, 2014) New research shows Gilead Science's drug Sovaldi helps in curing hepatitis C in those who suffer from HIV. In a medical study, the combination of Gilead's Hep C drug with anti-viral drug Ribavirin cured 76% of HIV-positive patients suffering from the most common hepatitis C strain. Hepatitis C and related complications have been a top cause of death in HIV-positive patients. Typical medication used to treat the disease, including interferon proteins, tended to react badly with HIV drugs. However, Sovaldi's %1,000-a-pill price tag could limit the number of patients able to access the treatment. TheStreet's Keris Lahiff reports from New York. Video provided by TheStreet
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins