Featured Research

from universities, journals, and other organizations

Major depression linked with nearly twice the risk of kidney failure in diabetics

Date:
March 27, 2014
Source:
American Society of Nephrology (ASN)
Summary:
Diabetics with major depressive symptoms had an 85% higher risk of developing kidney failure, results of a new study have concluded. Minor depressive symptoms were not significantly linked with the development of kidney failure among diabetics overall.

Major depression may increase diabetes patients' risk of developing kidney failure, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). Additional studies are needed to determine whether treatment for depression can improve kidney health in patients with diabetes.

Related Articles


Individuals with diabetes have a high prevalence of depressive symptoms, which has previously been linked with negative health outcomes such as cardiovascular disease and premature death. Little is known about depression's associations with long-term kidney health in diabetics, however.

To investigate, Margaret Yu, MD, MS and Bessie Young, MD, MPH (VA Puget Sound Health Care System and University of Washington) and their colleagues studied 3886 adults with diabetes who were covered by a large health maintenance organization in Washington State. A total of 448 (11.5%) of the patients had major and 327 (8.4%) had minor depressive symptoms. During a median follow-up of 8.8 years, 87 patients (2.2%) developed kidney failure.

Among the major findings:

• Patients with major depressive symptoms had an 85% higher risk of developing kidney failure, after adjusting for various factors including age, sex, race/ethnicity, marital status, education, smoking, body mass index, diabetes duration, baseline kidney function, hypertension, medication use, and adherence to diabetes self-care.

• Minor depressive symptoms were not significantly linked with the development of kidney failure.

"This is the first study to show that major depressive symptoms are associated with a higher risk of kidney failure in patients with diabetes," said Dr. Yu. "As an observational cohort study, we can only identify an association between major depressive symptoms and kidney failure; additional studies are needed to determine whether treatment of depression can reduce the risk of kidney failure."

Also, because the association was not entirely explained by differences in traditional risk factors for kidney disease or diabetes self-care characteristics, more research is needed to determine the mechanisms involved.


Story Source:

The above story is based on materials provided by American Society of Nephrology (ASN). Note: Materials may be edited for content and length.


Journal Reference:

  1. M. K. Yu, N. S. Weiss, X. Ding, W. J. Katon, X.-H. Zhou, B. A. Young. Associations between Depressive Symptoms and Incident ESRD in a Diabetic Cohort. Clinical Journal of the American Society of Nephrology, 2014; DOI: 10.2215/CJN.08670813

Cite This Page:

American Society of Nephrology (ASN). "Major depression linked with nearly twice the risk of kidney failure in diabetics." ScienceDaily. ScienceDaily, 27 March 2014. <www.sciencedaily.com/releases/2014/03/140327222208.htm>.
American Society of Nephrology (ASN). (2014, March 27). Major depression linked with nearly twice the risk of kidney failure in diabetics. ScienceDaily. Retrieved October 25, 2014 from www.sciencedaily.com/releases/2014/03/140327222208.htm
American Society of Nephrology (ASN). "Major depression linked with nearly twice the risk of kidney failure in diabetics." ScienceDaily. www.sciencedaily.com/releases/2014/03/140327222208.htm (accessed October 25, 2014).

Share This



More Health & Medicine News

Saturday, October 25, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Texas Nurse Nina Pham Cured of Ebola

Texas Nurse Nina Pham Cured of Ebola

AFP (Oct. 25, 2014) — An American nurse who contracted Ebola while caring for a Liberian patient in Texas has been declared free of the virus and will leave the hospital. Duration: 01:01 Video provided by AFP
Powered by NewsLook.com
IKEA Desk Converts From Standing to Sitting With One Button

IKEA Desk Converts From Standing to Sitting With One Button

Buzz60 (Oct. 24, 2014) — IKEA is out with a new convertible desk that can convert from a sitting desk to a standing one with just the push of a button. Jen Markham explains. Video provided by Buzz60
Powered by NewsLook.com
Ebola Protective Suits Being Made in China

Ebola Protective Suits Being Made in China

AFP (Oct. 24, 2014) — A factory in China is busy making Ebola protective suits for healthcare workers and others fighting the spread of the virus. Duration: 00:38 Video provided by AFP
Powered by NewsLook.com
WHO: Millions of Ebola Vaccine Doses by 2015

WHO: Millions of Ebola Vaccine Doses by 2015

AP (Oct. 24, 2014) — The World Health Organization said on Friday that millions of doses of two experimental Ebola vaccines could be ready for use in 2015 and five more experimental vaccines would start being tested in March. (Oct. 24) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins