Featured Research

from universities, journals, and other organizations

Heart disease risk tool tailored to rheumatoid arthritis patients

Date:
June 10, 2014
Source:
Mayo Clinic
Summary:
Rheumatoid arthritis patients overall are twice as likely as the average person to develop heart problems. Pinpointing which rheumatoid arthritis patients need stepped-up heart disease prevention efforts has been a challenge; research now has found that standard heart disease risk assessment tools may underrate the danger a particular person faces. To better pinpoint rheumatoid arthritis patients’ heart disease risk, an international team of researchers has created a heart disease risk calculator tailored to rheumatoid arthritis.

Rheumatoid arthritis patients overall are twice as likely as the average person to develop heart problems. Pinpointing which rheumatoid arthritis patients need stepped-up heart disease prevention efforts has been a challenge; research by Mayo Clinic and others has found that standard heart disease risk assessment tools may underrate the danger a particular person faces. To better pinpoint rheumatoid arthritis patients' heart disease risk, an international team that includes Mayo researchers has created a heart disease risk calculator tailored to rheumatoid arthritis.

Details on the new method, known as the Transatlantic Cardiovascular Risk Calculator for Rheumatoid Arthritis, or ATACC-RA, were presented at the European League Against Rheumatism annual meeting June 11-14 in Paris. The research team includes institutions from around the United States, Canada, Mexico, South Africa and Europe; Mayo is gathering and analyzing the group's data.

Initial findings show the new calculator is more effective for rheumatoid arthritis patients than standard heart disease risk calculators such as the Framingham and SCORE risk assessment tools. For example, of 314 rheumatoid arthritis patients studied who eventually developed heart problems, Framingham classified 54 percent, or 168 people, as high risk; ATACC-RA identified 201, or 64 percent, as high risk.

"There are completely new factors that are considered," says co-author Sherine Gabriel, M.D., a rheumatologist and epidemiologist at Mayo in Rochester. "What's unique about this calculator is that it incorporates rheumatoid arthritis disease characteristics into the assessment of cardiovascular risk."

Research by Mayo and others shows that major predictors of heart disease in rheumatoid arthritis have to do with the rheumatoid arthritis itself, including the disease, inflammation and perhaps treatments, Dr. Gabriel says. The new risk tool includes such factors; the Framingham and SCORE calculators do not.

The ATACC-RA calculator is designed to accurately predict rheumatoid arthritis patients' chances of developing heart disease within 10 years. The group plans further work to test and refine the calculator so it can be personalized for patients, says Dr. Gabriel, who is working with Mayo biostatistician Cynthia Crowson on the project.

The risk tool could also benefit people with other inflammatory rheumatic diseases that carry higher heart disease risk, such as lupus and psoriatic arthritis.

The international work to develop a better calculator is just part of the picture when it comes to stopping heart disease in rheumatoid arthritis patients. It is important for patients and physicians to be proactive, Dr. Gabriel says.

"I think it's important for patients with rheumatoid arthritis to understand that their disease alone carries added risk of heart disease and discuss that with their rheumatologist and perhaps suggest that their rheumatologist work with a cardiologist or a preventive cardiology clinic to come up with a plan to reduce cardiovascular risk," Dr. Gabriel says.

Mayo Clinic last year established a Cardio-Rheumatology Clinic to prevent heart disease in patients with chronic inflammatory forms of arthritis and to catch it early if it develops.


Story Source:

The above story is based on materials provided by Mayo Clinic. Note: Materials may be edited for content and length.


Cite This Page:

Mayo Clinic. "Heart disease risk tool tailored to rheumatoid arthritis patients." ScienceDaily. ScienceDaily, 10 June 2014. <www.sciencedaily.com/releases/2014/06/140610204859.htm>.
Mayo Clinic. (2014, June 10). Heart disease risk tool tailored to rheumatoid arthritis patients. ScienceDaily. Retrieved August 30, 2014 from www.sciencedaily.com/releases/2014/06/140610204859.htm
Mayo Clinic. "Heart disease risk tool tailored to rheumatoid arthritis patients." ScienceDaily. www.sciencedaily.com/releases/2014/06/140610204859.htm (accessed August 30, 2014).

Share This




More Health & Medicine News

Saturday, August 30, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

We've Got Mites Living In Our Faces And So Do You

We've Got Mites Living In Our Faces And So Do You

Newsy (Aug. 30, 2014) A new study suggests 100 percent of adult humans (those over 18 years of age) have Demodex mites living in their faces. Video provided by Newsy
Powered by NewsLook.com
Liberia Continues Fight Against Ebola

Liberia Continues Fight Against Ebola

AFP (Aug. 30, 2014) Authorities in Liberia try to stem the spread of the Ebola epidemic by raising awareness and setting up sanitation units for people to wash their hands. Duration: 00:41 Video provided by AFP
Powered by NewsLook.com
California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

California Passes 'yes-Means-Yes' Campus Sexual Assault Bill

Reuters - US Online Video (Aug. 30, 2014) California lawmakers pass a bill requiring universities to adopt "affirmative consent" language in their definitions of consensual sex, part of a nationwide drive to curb sexual assault on campuses. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
3 Things To Know About The Ebola Outbreak's Progression

3 Things To Know About The Ebola Outbreak's Progression

Newsy (Aug. 29, 2014) Here are three things you need to know about the deadly Ebola outbreak's progression this week. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins