Featured Research

from universities, journals, and other organizations

More Studies Needed To Determine Genetic Controls Of Il-4 Receptors In Allergies and Asthma, According To National Jewish Medical And Research Center Physician

Date:
December 10, 1997
Source:
National Jewish Medical And Research Center
Summary:
A National Jewish researcher who earlier reported genetic variations of interleukin-4 in people predisposed to asthma and allergies writes in tomorrow’s edition of the New England Journal of Medicine that new research increasing understanding of the role of IL-4 receptors in genetic predisposition to these diseases deserves continued exploration.

DENVER-A National Jewish Medical and Research Center researcher who earlier reported genetic variations of interleukin-4 in people predisposed to asthma and allergies writes in today’s edition of the New England Journal of Medicine that new research increasing understanding of the role of IL-4 receptors in genetic predisposition to these diseases deserves continued exploration.

Related Articles


"Research on genetic variations of IL-4 and IL-4 receptors will have value as markers for susceptibility and as models that may lead to innovative treatments for allergic disease and asthma," said Lanny Rosenwasser, M.D., head, Division of Allergy and Clinical Immunolgy at National Jewish.

The new research expands scientists’ understanding of IL-4 receptors. IL-4, a type of protein, or cytokine, released by cells when they come in contact with an allergen, causes the body’s immune system to release substances that cause inflammation in diseases such as asthma. IL-4 is also instrumental in causing the immune sytem to produce the allergic antibody IgE. When activated by an allergen entering the body, IL-4 binds to IL-4 receptors causing a series of immune responses by cells. These responses can cause inflammation of the airways.

In clinical trials at National Jewish, researchers are using a soluble form of IL-4 receptors to treat people with asthma who have a particularly high number of the IL-4 receptors. Researchers hope to "turn off" IL-4’s immune response to allergens.

For more information about National Jewish, call (800) 222-LUNG or visit http://www.nationaljewish.org/pa.


Story Source:

The above story is based on materials provided by National Jewish Medical And Research Center. Note: Materials may be edited for content and length.


Cite This Page:

National Jewish Medical And Research Center. "More Studies Needed To Determine Genetic Controls Of Il-4 Receptors In Allergies and Asthma, According To National Jewish Medical And Research Center Physician." ScienceDaily. ScienceDaily, 10 December 1997. <www.sciencedaily.com/releases/1997/12/971210111137.htm>.
National Jewish Medical And Research Center. (1997, December 10). More Studies Needed To Determine Genetic Controls Of Il-4 Receptors In Allergies and Asthma, According To National Jewish Medical And Research Center Physician. ScienceDaily. Retrieved March 4, 2015 from www.sciencedaily.com/releases/1997/12/971210111137.htm
National Jewish Medical And Research Center. "More Studies Needed To Determine Genetic Controls Of Il-4 Receptors In Allergies and Asthma, According To National Jewish Medical And Research Center Physician." ScienceDaily. www.sciencedaily.com/releases/1997/12/971210111137.htm (accessed March 4, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, March 4, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Adults Only Get The Flu Twice A Decade, Researchers Say

Adults Only Get The Flu Twice A Decade, Researchers Say

Newsy (Mar. 4, 2015) Researchers found adults only get the flu about once every five years. Scientists analyzed how a person&apos;s immunity builds up over time as well. Video provided by Newsy
Powered by NewsLook.com
New Hormone Could Protect Against Diabetes And Weight Gain

New Hormone Could Protect Against Diabetes And Weight Gain

Newsy (Mar. 4, 2015) A newly discovered hormone mimics the effects of exercise, protecting against diabetes and weight gain. Video provided by Newsy
Powered by NewsLook.com
Mount Everest Has a Poop Problem

Mount Everest Has a Poop Problem

Buzz60 (Mar. 4, 2015) With no bathrooms to use, climbers of Mount Everest have been leaving human waste on the mountain for years, and it&apos;s becoming a health issue. Mike Janela (@mikejanela) has more. Video provided by Buzz60
Powered by NewsLook.com
The Best Tips to 'Skinny' Your Home

The Best Tips to 'Skinny' Your Home

Buzz60 (Mar. 4, 2015) If you&apos;re looking to reach your health goals this season, there are a few simple tips to help you spring clean your space and improve your nutrition. Krystin Goodwin (@krystingoodwin) has the skinny on keeping a healthy home. Video provided by Buzz60
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins