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New Protein Found In Excessive Quantities In Alzheimer's Disease

Date:
December 16, 1997
Source:
Massachusetts General Hospital
Summary:
A research team based at the Massachusetts General Hospital has discovered a new gene that appears to play a role in Alzheimer's disease. The gene's protein is found in excessive quantities in brain tissue and cerebrospinal fluid of people with Alzheimer's and produces Alzheimer's-like damage in nerve cells.

A research team based at the Massachusetts General Hospital (MGH) has discovered a new gene that appears to play a role in Alzheimer's disease. The gene produces a protein in nerve cells, and the researchers found excessive quantities of this protein in brain tissue and cerebrospinal fluid (CSF) of people with Alzheimer's. They also showed that accumulation in nerve cells of this protein, called AD7c-NTP, causes changes similar to those seen in Alzheimer's, including cell death. Published in the December issue of the Journal of Clinical Investigation, the study additionally describes a highly sensitive and specific assay for AD7c-NTP, developed by scientists from the Nymox Corporation.


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The above story is based on materials provided by Massachusetts General Hospital. Note: Materials may be edited for content and length.


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Massachusetts General Hospital. "New Protein Found In Excessive Quantities In Alzheimer's Disease." ScienceDaily. ScienceDaily, 16 December 1997. <www.sciencedaily.com/releases/1997/12/971216045921.htm>.
Massachusetts General Hospital. (1997, December 16). New Protein Found In Excessive Quantities In Alzheimer's Disease. ScienceDaily. Retrieved April 20, 2014 from www.sciencedaily.com/releases/1997/12/971216045921.htm
Massachusetts General Hospital. "New Protein Found In Excessive Quantities In Alzheimer's Disease." ScienceDaily. www.sciencedaily.com/releases/1997/12/971216045921.htm (accessed April 20, 2014).

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