Featured Research

from universities, journals, and other organizations

Toxicity Of Cigarette Smoking Linked To DNA Damage From Tar Extracts

Date:
April 23, 1998
Source:
American Chemical Society
Summary:
Cigarette tar is deposited in the lungs of smokers, and these lung tissues are continuously bathed in an aqueous solution that can dissolve and transport the water-soluble chemicals in the tar.

The following research article will appear April 21 in the Web edition of Chemical Research in Toxicology, a peer-reviewed journal published by the American Chemical Society, the world's largest scientific society.

Related Articles


Cigarette tar is deposited in the lungs of smokers, and these lung tissues are continuously bathed in an aqueous solution that can dissolve and transport the water-soluble chemicals in the tar. According to William A. Pryor, Ph.D., Director of the Biodynamics Institute at Louisiana State University, this aqueous cigarette tar (ACT) extract is a complex mixture of hundreds of compounds that can cause DNA damage. Now Pryor's research has shown that some of the most active compounds in ACT are compounds called hydroquinones, and their derivatives, quinones and semiquinones. (Semiquinones are free radicals -- reactive chemical species that have an odd number of electrons.) Using mammalian cells, Pryor has shown that these semiquinone free radicals are critically involved in causing DNA damage of a type that is not easily repaired and therefore might lead to mutations and cancer. "It is very likely that these highly reactive free radicals are involved in the toxicity associated with cigarette smoking," Pryor says.

A nonprofit organization with a membership of more than 155,000 chemists and chemical engineers, the American Chemical Society publishes scientific journals, convenes major research conferences, and provides educational, science policy and career programs in chemistry. Its main offices are in Washington, D.C., and Columbus, Ohio.


Story Source:

The above story is based on materials provided by American Chemical Society. Note: Materials may be edited for content and length.


Cite This Page:

American Chemical Society. "Toxicity Of Cigarette Smoking Linked To DNA Damage From Tar Extracts." ScienceDaily. ScienceDaily, 23 April 1998. <www.sciencedaily.com/releases/1998/04/980423070618.htm>.
American Chemical Society. (1998, April 23). Toxicity Of Cigarette Smoking Linked To DNA Damage From Tar Extracts. ScienceDaily. Retrieved February 27, 2015 from www.sciencedaily.com/releases/1998/04/980423070618.htm
American Chemical Society. "Toxicity Of Cigarette Smoking Linked To DNA Damage From Tar Extracts." ScienceDaily. www.sciencedaily.com/releases/1998/04/980423070618.htm (accessed February 27, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, February 27, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

New FDA-Approved Diabetes Medicine Might Save Drugmaker

New FDA-Approved Diabetes Medicine Might Save Drugmaker

Newsy (Feb. 26, 2015) The U.S. Food and Drug Administration approved new diabetes drug Toujeo on Wednesday, a move that might save French drugmaker Sanofi&apos;s profits. Video provided by Newsy
Powered by NewsLook.com
The Best Foods to Battle Stress

The Best Foods to Battle Stress

Buzz60 (Feb. 26, 2015) If you&apos;re dealing with anxiety, there are a few foods that can help. Krystin Goodwin (@krystingoodwin) has the best foods to tame stress. Video provided by Buzz60
Powered by NewsLook.com
The 5 Best Tips to Look Younger Now

The 5 Best Tips to Look Younger Now

Buzz60 (Feb. 26, 2015) Life happens, and we all get older, but forget the pricey anti-aging products and plastic surgery. You can tweak your habits to turn back the hands of time. Krystin Goodwin (@krystingoodwin) has a few simple tips to help you look and feel younger. Video provided by Buzz60
Powered by NewsLook.com
Sleeping Too Much Or Too Little Might Increase Stroke Risk

Sleeping Too Much Or Too Little Might Increase Stroke Risk

Newsy (Feb. 26, 2015) People who sleep more than eight hours per night are 45 percent more likely to have a stroke, according to a University of Cambridge study. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins