Human Biology News
June 29, 2015

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More Human Biology News
June 29, 2015

Upsetting a Fragile Alliance Triggers a Deadly Childhood Disease

June 29, 2015 — SMA is a devastating neuromuscular disorder that robs children of their ability to walk, eat, or breathe. Mostly caused by an inherited flaw in the Survival Motor Neuron (SMN) gene, SMA is presently ... read more

RNASEH1 Mutations Impair mtDNA Replication, Cause Adult-Onset Mitochondrial Encephalomyopathy

June 26, 2015 — Next Generation Sequencing (NGS) technology offers an incredible opportunity for the rapid and relatively low-cost characterization of individual genomes, giving us a chance to make a substantial ... read more

A Novel DNA Damage Alarm

June 25, 2015 — How does our body keep its DNA intact? Researchers have just found a new piece of this puzzle. They discovered a novel alarm that cells use to signal DNA ... read more

June 25, 2015 — A team of scientists has developed a method for dividing a DNA sample into thousands of tiny droplets. What sets it apart from previous methods is above all the fact that it is considerably easier to ... read more

DNA Shed from Head and Neck Tumors Detected in Blood, Saliva

June 24, 2015 — On the hunt for better cancer screening tests, scientists led a proof of principle study that successfully identified tumor DNA shed into the blood and saliva of 93 patients with head and neck ... read more

June 24, 2015 — Telomeres, specialized ends of our chromosomes that dictate how long cells can continue to duplicate themselves, have long been studied for their links to the aging process and cancer. In an ... read more

Tiny Particles in Blood Useful for Early Diagnosis of Pancreatic Cancer

June 24, 2015 — A protein encoded by the gene glypican-1 (GPC1) present on cancer exosomes may be used as part of a potential non-invasive diagnostic and screening tool to detect early pancreatic cancer, potentially ... read more

Low-Grade Brain Tumor Diagnosis Redefined

June 24, 2015 — A group of patients have made important contributions to an American cancer study that proposes a change in how some brain tumors are classified and ultimately treated. The study reveals that a ... read more

Study Identifies Multiple Genetic Changes Linked to Increased Pancreatic Cancer Risk

June 23, 2015 — In a genome-wide association study believed to be the largest of its kind, researchers have uncovered four regions in the human genome where changes may increase the risk of pancreatic ... read more

June 23, 2015 — Groundbreaking new reproductive research has identified key molecular events that could be playing a critical role as sperm and egg fuse to create new life. The findings might one day lead to the ... read more

June 23, 2015 — In an apparent effort to help themselves, inflamed kidney cells produce one of the same inflammation-suppressing enzymes fetuses use to survive, researchers ... read more

Big Data Analysis Platform to Unveil Gene Interactions in Cancer

June 23, 2015 — A breakthrough in cancer genomics has been achieved by developing a novel big data analysis platform for analyzing the interactions among genes. The analysis platform unveils the unregulated patterns ... read more

June 23, 2015 — A promising biomarker for the severity of age-related white matter changes (ARWMCs) and endothelial function was recently evaluated. The researchers investigated the association between the telomere ... read more

Research Team Evolves CRISPR-Cas9 Nucleases With Novel Properties

June 22, 2015 — A team of researchers has found a way to expand the use and precision of the powerful gene-editing tools called CRISPR-Cas9 RNA-guided nucleases. In their report, the investigators describe evolved ... read more

June 22, 2015 — Using X-rays, scientists measured the ultrafast response of DNA nucleobases to UV light. They found that the UV excited state in the nucleobase thymine decays rapidly, harmlessly dissipating the ... read more

June 19, 2015 — DNA naturally folds itself into cross-shaped structures called cruciforms that jut out along the sprawling length of its double helix. DNA cruciforms are abundant; scientists estimate as many as ... read more

Health Records and Genetic Data from More Than 100,000 Californians Power Medical Research

June 19, 2015 — By volunteering to mail saliva to researchers working with their health care provider, thousands of people in California have helped build one of the nation's most powerful medical research ... read more

Simultaneous Live Imaging of a Specific Gene's Transcription, Dynamics

June 19, 2015 — A research group has developed a live-imaging method for simultaneous measurements of the transcriptional activity and nuclear position of endogenous genes. This method is used to detect ... read more

Genomics Holds Key to Understanding Ecological, Evolutionary Processes

June 19, 2015 — Scientists believe that Next-Generation Sequencing (NGS) of invasive organisms holds the key to furthering our understanding of ecological and evolutionary processes. In a review of recent studies, ... read more

Mapping Genetic Mutations in Skin Cancer

June 18, 2015 — A study by The Cancer Genome Atlas network of researchers refined and revealed molecular sub-groups of patients with cutaneous melanoma who could potentially benefit from targeted treatments based on ... read more

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