Human Biology News
October 13, 2015

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updated 2:58am EDT

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October 13, 2015

Turncoat Protein Regulates Sensitivity of Breast Cancer Cells to Drug

Oct. 12, 2015 — A surprising, paradoxical relationship between a tumor suppressor molecule and an oncogene may be the key to explaining and working around how breast cancer tumor cells become desensitized to a ... read more

Immune Gene Prevents Parkinson's Disease, Dementia

Oct. 9, 2015 — An estimated seven to ten million people worldwide are living with Parkinson's disease (PD). More than half of PD patients develop progressive disease showing signs of dementia similar to ... read more

Common Gene Variant Linked to Chromosome Errors, Early Pregnancy Loss

Oct. 8, 2015 — Researchers have identified a common genetic variant strongly associated with chromosome gains and losses during the early stages of human embryonic development. These errors in cell division, which ... read more

Oct. 8, 2015 — Biochemists have long known that crucial cell processes depend on a highly regulated cleanup system known as proteolysis, where specialized proteins called proteases degrade damaged or ... read more

Genetic Variation Is Key to Fighting Viruses

Oct. 8, 2015 — Using a genome-wide association study, scientists have identified subtle genetic changes that can cause substantial differences to how we fight viral infections. The new work connects genetics to ... read more

Oct. 8, 2015 — Our cells contain proteins, essential to functions like protein creation and DNA repair but also involved in forms of ALS and cancer, that never take a characteristic shape, a new study shows. ... read more

Oct. 8, 2015 — A new technique allows scientists to study diseases like Alzheimer's and Parkinson's using cells from human patients. Historically, animal models -- from fruit flies to mice -- have been ... read more

Oct. 8, 2015 — Compared with direct gene injection, cell-mediated GDNF gene delivery led to considerably more pronounced preservation of myelinated fibers in the remote segments of the spinal cord (5 vs 3 mm from ... read more

Oct. 8, 2015 — The organization of DNA packaged in chromosomes during cell division has been very difficult to study experimentally. Researchers have found that the structure of translocations in cancer cells shows ... read more

'Alarm Clock' of a Leukemia-Causing Oncogene Identified

Oct. 8, 2015 — Mutations in DNMT3A gene cause MEIS1 activacion, triggering leukemia, a research team ... read more

Oct. 8, 2015 — The organization of DNA packaged in chromosomes during cell division has been very difficult to study experimentally. Researchers from the Universitat Autònoma de Barcelona have found that the ... read more

'Chromosomal Chaos:' Complex Array of Mutations Found in Rare, Aggressive Leukemia

Oct. 7, 2015 — Sezary syndrome (SS), an aggressive leukemia of mature T cells, is more complicated at a molecular level than ever suspected. With a poor prognosis and limited options for targeted therapies, this ... read more

Shaking Up the Foundations of Epigenetics

Oct. 7, 2015 — Cells of multicellular organisms contain identical genetic material (the genome) yet can have drastic differences in their structural arrangements and functions. This variation of the distinct cell ... read more

New Player Found in Tumor Suppression, Aging

Oct. 7, 2015 — The protective role played by a little-known protein complex, SMC 5/6, in cancer and aging has been revealed by new research. These results emphasize, once more, the relationship between these two ... read more

Groundbreaking Computer Program Diagnoses Cancer in Two Days

Oct. 7, 2015 — In about one in 20 cancer cases, the doctor can confirm that the patient has cancer -- but cannot find the source. These patients then face the prospect of a long wait with numerous diagnostic tests ... read more

Oct. 7, 2015 — The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry for 2015 to Tomas Lindahl Francis Crick Institute and Clare Hall Laboratory, Hertfordshire, UK, Paul Modrich ... read more

Oct. 7, 2015 — An international team of researchers have designed and synthesized a nanometer-scale DNA 'machine' whose customized modifications enable it to recognize a specific target ... read more

Studies Suggest New Ways to Inhibit Oncogenes, Enhance Tumor-Suppressor Activity

Oct. 6, 2015 — Two studies suggest new approaches for treating cancer by inhibiting overactive cancer-promoting genes and by enhancing the activity of sluggish tumor-suppressor ... read more

Oct. 6, 2015 — In what is believed to be a first, artificial intelligence (AI) has been used to discover a molecular model that explains deviations from normal embryonic development. Scientists applied AI that ... read more

Unlikely Partners? Cell's Waste Disposal System Regulates Body Clock Proteins

Oct. 6, 2015 — Researchers have a new genome screen that has identified partner molecules of cell-waste disposal proteins. They applied their new method to identify other clock partners that target a multipurpose ... read more

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