Human Biology News
February 7, 2016

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More Human Biology News
February 7, 2016

Single-Lesion Biopsy May Be Insufficient to Choose Therapy Targeting Resistance Mutations

Feb. 5, 2016 — When metastatic tumors driven by drug-targetable genetic mutations become resistant to a targeted therapy drug, the usual practice is to test a single metastatic lesion for new mutations that can ... read more

New Analysis Method May Reduce Need for Invasive Biopsies

Feb. 5, 2016 — Scientists have identified a quantitative method to measure changes in biomarkers, which may reduce or eliminate the need for invasive ... read more

Feb. 5, 2016 — IBS researchers create multiplex Digenome-seq to find errors in CRISPR-Cas9 ... read more

Fast, Accurate Cystic Fibrosis Test Developed

Feb. 4, 2016 — Researchers have developed a fast, inexpensive and highly accurate test to screen newborns for cystic fibrosis. The new method detects virtually all mutations in the CF gene, preventing missed ... read more

Genetic Cause of Rare Allergy to Vibration Discovered

Feb. 3, 2016 — Scientists have identified a genetic mutation responsible for a rare form of inherited hives induced by vibration, also known as vibratory urticaria. Running, hand clapping, towel drying or even ... read more

Feb. 3, 2016 — A new way to use the empty shell of a hepatitis E virus has been developed to carry vaccines or drugs into the body. The technique has been tested in rodents as a way to target breast cancer, and is ... read more

Clinical Investigations of Mitochondrial Replacement Techniques Are 'Ethically Permissible' If Conditions Met

Feb. 3, 2016 — Conducting clinical investigations of mitochondrial replacement techniques in humans is ethically permissible as long as significant conditions and principles are met, says a new ... read more

Feb. 3, 2016 — A powerful, three-way mechanism by which a mutation drives the growth of childhood brain cancers, was discovered by scientists. The team hopes the discovery will lead to better methods for diagnosing ... read more

Feb. 3, 2016 — For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds ... read more

Sstudy Identifies Mechanism for Drug Target to Help Block HIV's Ability to Spread

Feb. 2, 2016 — A new study identifies how RNA-based drug 5-aza-C blocks HIV's ability to spread by converting to DNA before infiltrating the virus. Because RNA drugs are more cost-effective, the findings could ... read more

Feb. 2, 2016 — It is normal -- in fact necessary -- for our immune system to occasionally fly into an inflammatory rage to defend the host (us) against pathogens or even tumor cells. Problems arise when the rage ... read more

Feb. 2, 2016 — Researchers have found evidence that a “housekeeping” gene present in every cell of the body may have a link to male infertility. The results of the study suggest that deficiency of the SMN gene ... read more

Adenosine Deaminase May Help the Immune System Fight HIV on Its Own

Feb. 2, 2016 — A new therapeutic strategy for HIV may already be available by repurposing an existing prescription drug, new research shows. The drug, an enzyme called adenosine deaminase, or ADA, ultimately may be ... read more

Biomolecule's Behavior Under Artificial Conditions More Natural Than Expected

Feb. 2, 2016 — Researchers often analyze isolated biomolecules in test tubes, and it is doubtful if the results can be applied to densely-packed cells. A team of researchers monitored the folding of an RNA ... read more

Cell Insight Offers Clues on Biological Processes Linked to Fertility

Feb. 2, 2016 — Congenital disorders such as Down's syndrome could be better understood, following new insights into how healthy cells are formed. Scientists have identified a set of proteins that play a key ... read more

Feb. 2, 2016 — A large-scale study based on almost 7,000 strains of Listeria monocytogenes -- the bacterium responsible for human listeriosis, a severe foodborne infection -- has concluded. Through the integrative ... read more

'Junk' DNA Plays Role in Preventing Breast Cancer

Feb. 2, 2016 — Supposed 'junk' DNA, found in between genes, plays a role in suppressing cancer, according to new research. The human genome contains around three meters of DNA, of which only about two per ... read more

Feb. 1, 2016 — It has long been thought that cancer metastasizes, or spreads, when a single cancer cell escapes from the original tumor, travels through the bloodstream and sets up shop in distant organs. However, ... read more

Feb. 1, 2016 — When the process of epigenetic reprogramming is defective in mouse development, the consequences in adulthood can include abnormal repetitive behaviors, scientists have ... read more

Feb. 1, 2016 — A genetic mechanism that is likely to drive mutations that can lead to cancer has been discovered by scientists. The study finds the enzyme APOBEC3G -- a known trigger for mutations that occur as ... read more

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