Human Biology News
February 6, 2016

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updated 10:30am EST

More Human Biology News
February 6, 2016

Feb. 3, 2016 — A powerful, three-way mechanism by which a mutation drives the growth of childhood brain cancers, was discovered by scientists. The team hopes the discovery will lead to better methods for diagnosing ... read more

Feb. 3, 2016 — For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds ... read more

Sstudy Identifies Mechanism for Drug Target to Help Block HIV's Ability to Spread

Feb. 2, 2016 — A new study identifies how RNA-based drug 5-aza-C blocks HIV's ability to spread by converting to DNA before infiltrating the virus. Because RNA drugs are more cost-effective, the findings could ... read more

Feb. 2, 2016 — It is normal -- in fact necessary -- for our immune system to occasionally fly into an inflammatory rage to defend the host (us) against pathogens or even tumor cells. Problems arise when the rage ... read more

Adenosine Deaminase May Help the Immune System Fight HIV on Its Own

Feb. 2, 2016 — A new therapeutic strategy for HIV may already be available by repurposing an existing prescription drug, new research shows. The drug, an enzyme called adenosine deaminase, or ADA, ultimately may be ... read more

Biomolecule's Behavior Under Artificial Conditions More Natural Than Expected

Feb. 2, 2016 — Researchers often analyze isolated biomolecules in test tubes, and it is doubtful if the results can be applied to densely-packed cells. A team of researchers monitored the folding of an RNA ... read more

Cell Insight Offers Clues on Biological Processes Linked to Fertility

Feb. 2, 2016 — Congenital disorders such as Down's syndrome could be better understood, following new insights into how healthy cells are formed. Scientists have identified a set of proteins that play a key ... read more

Feb. 2, 2016 — A large-scale study based on almost 7,000 strains of Listeria monocytogenes -- the bacterium responsible for human listeriosis, a severe foodborne infection -- has concluded. Through the integrative ... read more

'Junk' DNA Plays Role in Preventing Breast Cancer

Feb. 2, 2016 — Supposed 'junk' DNA, found in between genes, plays a role in suppressing cancer, according to new research. The human genome contains around three meters of DNA, of which only about two per ... read more

Feb. 1, 2016 — When the process of epigenetic reprogramming is defective in mouse development, the consequences in adulthood can include abnormal repetitive behaviors, scientists have ... read more

Feb. 1, 2016 — A genetic mechanism that is likely to drive mutations that can lead to cancer has been discovered by scientists. The study finds the enzyme APOBEC3G -- a known trigger for mutations that occur as ... read more

Making the Leap from Sequence Data to Actionable Targets in Clinical Oncology

Feb. 1, 2016 — The ever-shrinking cost of DNA sequencing improves accessibility for an increasing number of people and, importantly, for the diagnosis and treatment of disease. This is particularly salient in ... read more

Researchers Work to Unravel the Complex Genetic Disease Neurofibromatosis Type 1

Feb. 1, 2016 — From a collection of more than 7,800 unrelated neurofibromatosis type 1 mutations, researchers have aimed at two goals: correlate a particular mutation with the symptoms that will develop as the ... read more

Researchers Identify Way Radiation May Fight Cancer Cells Escaping Immune System

Feb. 1, 2016 — A team of researchers is fighting cancers using a combination of therapies and recently found ways that radiation could maximize responses to novel immune-based therapeutic approaches to fight ... read more

CRISPR/Cas9 Therapeutic for Tyrosinemai Type I Delivered to Mice

Feb. 1, 2016 — A more efficient delivery of a CRISPR/Cas9 therapeutic to adult mice with the metabolic disease Tyrosinemia type I developed may also prove to be safer for use in humans. A study shows that the ... read more

Targeting Upper Motor Neurons to Treat ALS

Feb. 1, 2016 — Scientists have demonstrated for the first time that it is possible to specifically modify gene expression in diseased upper motor neurons, brain cells that break down in ALS. The study provides ... read more

Feb. 1, 2016 — Biologists have modified a harmless virus in such a way that it can successfully enter the adult mouse brain through the bloodstream and deliver genes to cells of the nervous system. The virus could ... read more

Feb. 1, 2016 — The genome-editing technique known as CRISPR allows scientists to clip a specific DNA sequence and replace it with a new one, offering the potential to cure diseases caused by defective genes. For ... read more

Abnormal Gene Is a Triple Threat in Driving Pediatric Brain Tumors

Feb. 1, 2016 — An abnormal fused gene that drives pediatric brain tumors poses a triple threat, operating simultaneously through three distinct biological mechanisms -- the first such example in cancer biology. ... read more

Feb. 1, 2016 — For the first time, researchers have treated an animal model of a genetic disorder using a viral vector to deliver genome-editing components in which the disease- causing mutation has been corrected. ... read more

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