Human Biology News
October 13, 2015

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October 13, 2015

New Research Sees Zebrafish Earn Their Stripes in the Fight Against Muscular Dystrophy

Oct. 13, 2015 — New research has demonstrated a new method for observing the behavior of the protein Dystrophin in a living animal cell, in real-time. This breakthrough may provide a key to understanding how to ... read more

Turncoat Protein Regulates Sensitivity of Breast Cancer Cells to Drug

Oct. 12, 2015 — A surprising, paradoxical relationship between a tumor suppressor molecule and an oncogene may be the key to explaining and working around how breast cancer tumor cells become desensitized to a ... read more

RNA's Part in Determining the Health of Stem Cells

Oct. 12, 2015 — What makes stem cells so interesting is that they are pluripotent: they have the potential to become any cell in an organism. Their ability to differentiate into any cell and be used to replace those ... read more

Immune Gene Prevents Parkinson's Disease, Dementia

Oct. 9, 2015 — An estimated seven to ten million people worldwide are living with Parkinson's disease (PD). More than half of PD patients develop progressive disease showing signs of dementia similar to ... read more

Common Gene Variant Linked to Chromosome Errors, Early Pregnancy Loss

Oct. 8, 2015 — Researchers have identified a common genetic variant strongly associated with chromosome gains and losses during the early stages of human embryonic development. These errors in cell division, which ... read more

Researchers Create 'Leukemia in a Dish' to Better Study It

Oct. 8, 2015 — Scientists engineered stem cells to better understand the mechanisms behind a form of leukemia caused by changes in a key gene, according to a new ... read more

A Convergence of Deadly Signals

Oct. 8, 2015 — A team of Ludwig Cancer Research scientists has mapped out how a mutant version of the epidermal growth factor receptor (EGFR) known as EGFRvIII specifically drives critical processes that alter the ... read more

Oct. 8, 2015 — Biochemists have long known that crucial cell processes depend on a highly regulated cleanup system known as proteolysis, where specialized proteins called proteases degrade damaged or ... read more

Genetic Variation Is Key to Fighting Viruses

Oct. 8, 2015 — Using a genome-wide association study, scientists have identified subtle genetic changes that can cause substantial differences to how we fight viral infections. The new work connects genetics to ... read more

Oct. 8, 2015 — Our cells contain proteins, essential to functions like protein creation and DNA repair but also involved in forms of ALS and cancer, that never take a characteristic shape, a new study shows. ... read more

Oct. 8, 2015 — A new technique allows scientists to study diseases like Alzheimer's and Parkinson's using cells from human patients. Historically, animal models -- from fruit flies to mice -- have been ... read more

Oct. 8, 2015 — Compared with direct gene injection, cell-mediated GDNF gene delivery led to considerably more pronounced preservation of myelinated fibers in the remote segments of the spinal cord (5 vs 3 mm from ... read more

Oct. 8, 2015 — The organization of DNA packaged in chromosomes during cell division has been very difficult to study experimentally. Researchers have found that the structure of translocations in cancer cells shows ... read more

'Alarm Clock' of a Leukemia-Causing Oncogene Identified

Oct. 8, 2015 — Mutations in DNMT3A gene cause MEIS1 activacion, triggering leukemia, a research team ... read more

Oct. 8, 2015 — The organization of DNA packaged in chromosomes during cell division has been very difficult to study experimentally. Researchers from the Universitat Autònoma de Barcelona have found that the ... read more

'Chromosomal Chaos:' Complex Array of Mutations Found in Rare, Aggressive Leukemia

Oct. 7, 2015 — Sezary syndrome (SS), an aggressive leukemia of mature T cells, is more complicated at a molecular level than ever suspected. With a poor prognosis and limited options for targeted therapies, this ... read more

Shaking Up the Foundations of Epigenetics

Oct. 7, 2015 — Cells of multicellular organisms contain identical genetic material (the genome) yet can have drastic differences in their structural arrangements and functions. This variation of the distinct cell ... read more

New Player Found in Tumor Suppression, Aging

Oct. 7, 2015 — The protective role played by a little-known protein complex, SMC 5/6, in cancer and aging has been revealed by new research. These results emphasize, once more, the relationship between these two ... read more

Groundbreaking Computer Program Diagnoses Cancer in Two Days

Oct. 7, 2015 — In about one in 20 cancer cases, the doctor can confirm that the patient has cancer -- but cannot find the source. These patients then face the prospect of a long wait with numerous diagnostic tests ... read more

Oct. 7, 2015 — The Royal Swedish Academy of Sciences has decided to award the Nobel Prize in Chemistry for 2015 to Tomas Lindahl Francis Crick Institute and Clare Hall Laboratory, Hertfordshire, UK, Paul Modrich ... read more

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