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Relapses Prevented In Mouse Model Of Multiple Sclerosis: Research Aimed At Treating Relapses In Human MS

Date:
November 3, 1998
Source:
University Of Pennsylvania Medical Center
Summary:
Researchers at the University of Pennsylvania Medical Center have discovered that antibodies to a common inflammatory-response protein can prevent relapses in an animal model of human multiple sclerosis.

Researchers at the University of Pennsylvania Medical Center have discovered that antibodies to a common inflammatory-response protein can prevent relapses in an animal model of human multiple sclerosis. "We have been able to prevent relapses in the mouse version of multiple sclerosis using anti-interleukin-12 antibodies for the first time," says Mohamad Rostami, MD, PhD, professor of neurology at Penn's School of Medicine. "Most treatments for MS are first tried out in the experimental allergic encephalomyelitis, or EAE, animal model of MS, before being tested in humans, so this research represents another possible therapy for MS patients." Rostami, Cris Constantinescu, a doctoral student in Rostami's laboratory, and colleagues report their findings in the November 1 issue of the Journal of Immunology.


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The above story is based on materials provided by University Of Pennsylvania Medical Center. Note: Materials may be edited for content and length.


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University Of Pennsylvania Medical Center. "Relapses Prevented In Mouse Model Of Multiple Sclerosis: Research Aimed At Treating Relapses In Human MS." ScienceDaily. ScienceDaily, 3 November 1998. <www.sciencedaily.com/releases/1998/10/981031180233.htm>.
University Of Pennsylvania Medical Center. (1998, November 3). Relapses Prevented In Mouse Model Of Multiple Sclerosis: Research Aimed At Treating Relapses In Human MS. ScienceDaily. Retrieved April 21, 2014 from www.sciencedaily.com/releases/1998/10/981031180233.htm
University Of Pennsylvania Medical Center. "Relapses Prevented In Mouse Model Of Multiple Sclerosis: Research Aimed At Treating Relapses In Human MS." ScienceDaily. www.sciencedaily.com/releases/1998/10/981031180233.htm (accessed April 21, 2014).

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