Featured Research

from universities, journals, and other organizations

Kentucky Researchers Find Way To Speed Response Of Viagra

Date:
January 7, 1999
Source:
University Of Kentucky Medical Center
Summary:
Two University of Kentucky College of Pharmacy faculty members have developed a nasal drug delivery system for Viagra causing the drug to work almost immediately after dosing.

Two University of Kentucky College of Pharmacy faculty members have developed a nasal drug delivery system for Viagra causing the drug to work almost immediately after dosing.

A problem with the Viagra tablet, approved last March for impotency in men, is that it can take an hour or more for the drug to take effect, said Lewis Dittert, Ph.D., professor in the UK College of Pharmacy.

"If a man takes Viagra and gets no response, he may become impatient and after 30 to 45 minutes be tempted to take one or two more tablets, just as the first one is being absorbed," Dittert said. "The result would be an overdose."

Dittert and Anwar Hussain, Ph.D., professor in the UK College of Pharmacy, developed the nasal spray at their company, New Millennium Pharmaceutical Research Inc. (NMPRI) located at Advanced Science and Technology Commercialization Center (ASTeCC) on the UK campus.

The active ingredient in the Viagra tablet is poorly soluble in water and becomes even less soluble when it reaches the small intestine where it is absorbed by the blood, Dittert said.

The advantage of the intranasal route is the drug is transferred directly into the blood without being exposed to the alkaline intestinal fluids. UK researchers also have made the active ingredient into an aqueous solution and made it soluble in water.

Hussain has studied nasal drug delivery systems for more than 15 years and Dittert for more than 10 years.


Story Source:

The above story is based on materials provided by University Of Kentucky Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

University Of Kentucky Medical Center. "Kentucky Researchers Find Way To Speed Response Of Viagra." ScienceDaily. ScienceDaily, 7 January 1999. <www.sciencedaily.com/releases/1999/01/990107073804.htm>.
University Of Kentucky Medical Center. (1999, January 7). Kentucky Researchers Find Way To Speed Response Of Viagra. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/1999/01/990107073804.htm
University Of Kentucky Medical Center. "Kentucky Researchers Find Way To Speed Response Of Viagra." ScienceDaily. www.sciencedaily.com/releases/1999/01/990107073804.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC Revamps Ebola Guidelines After Criticism

CDC Revamps Ebola Guidelines After Criticism

Newsy (Oct. 21, 2014) The Centers for Disease Control and Prevention have issued new protocols for healthcare workers interacting with Ebola patients. Video provided by Newsy
Powered by NewsLook.com
WHO: Ebola Vaccine Trials to Start a in January

WHO: Ebola Vaccine Trials to Start a in January

AP (Oct. 21, 2014) Tens of thousands of doses of experimental Ebola vaccines could be available for "real-world" testing in West Africa as soon as January as long as they are deemed safe in soon to start trials, the World Health Organization said Tuesday. (Oct. 21) Video provided by AP
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
CDC Issues New Ebola Guidelines for Health Workers

CDC Issues New Ebola Guidelines for Health Workers

Reuters - US Online Video (Oct. 21, 2014) The U.S. Centers for Disease Control and Prevention has set up new guidelines for health workers taking care of patients infected with Ebola. Linda So reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins