Featured Research

from universities, journals, and other organizations

Kentucky Researchers Find Way To Speed Response Of Viagra

Date:
January 7, 1999
Source:
University Of Kentucky Medical Center
Summary:
Two University of Kentucky College of Pharmacy faculty members have developed a nasal drug delivery system for Viagra causing the drug to work almost immediately after dosing.

Two University of Kentucky College of Pharmacy faculty members have developed a nasal drug delivery system for Viagra causing the drug to work almost immediately after dosing.

A problem with the Viagra tablet, approved last March for impotency in men, is that it can take an hour or more for the drug to take effect, said Lewis Dittert, Ph.D., professor in the UK College of Pharmacy.

"If a man takes Viagra and gets no response, he may become impatient and after 30 to 45 minutes be tempted to take one or two more tablets, just as the first one is being absorbed," Dittert said. "The result would be an overdose."

Dittert and Anwar Hussain, Ph.D., professor in the UK College of Pharmacy, developed the nasal spray at their company, New Millennium Pharmaceutical Research Inc. (NMPRI) located at Advanced Science and Technology Commercialization Center (ASTeCC) on the UK campus.

The active ingredient in the Viagra tablet is poorly soluble in water and becomes even less soluble when it reaches the small intestine where it is absorbed by the blood, Dittert said.

The advantage of the intranasal route is the drug is transferred directly into the blood without being exposed to the alkaline intestinal fluids. UK researchers also have made the active ingredient into an aqueous solution and made it soluble in water.

Hussain has studied nasal drug delivery systems for more than 15 years and Dittert for more than 10 years.


Story Source:

The above story is based on materials provided by University Of Kentucky Medical Center. Note: Materials may be edited for content and length.


Cite This Page:

University Of Kentucky Medical Center. "Kentucky Researchers Find Way To Speed Response Of Viagra." ScienceDaily. ScienceDaily, 7 January 1999. <www.sciencedaily.com/releases/1999/01/990107073804.htm>.
University Of Kentucky Medical Center. (1999, January 7). Kentucky Researchers Find Way To Speed Response Of Viagra. ScienceDaily. Retrieved August 23, 2014 from www.sciencedaily.com/releases/1999/01/990107073804.htm
University Of Kentucky Medical Center. "Kentucky Researchers Find Way To Speed Response Of Viagra." ScienceDaily. www.sciencedaily.com/releases/1999/01/990107073804.htm (accessed August 23, 2014).

Share This




More Health & Medicine News

Saturday, August 23, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Drug Used To Treat 'Ebola's Cousin' Shows Promise

Newsy (Aug. 21, 2014) An experimental drug used to treat Marburg virus in rhesus monkeys could give new insight into a similar treatment for Ebola. Video provided by Newsy
Powered by NewsLook.com
Two US Ebola Patients Leave Hospital Free of the Disease

Two US Ebola Patients Leave Hospital Free of the Disease

AFP (Aug. 21, 2014) Two American missionaries who were sickened with Ebola while working in Liberia and were treated with an experimental drug are doing better and have left the hospital, doctors say on August 21, 2014. Duration: 01:05 Video provided by AFP
Powered by NewsLook.com
Cadavers, a Teen, and a Medical School Dream

Cadavers, a Teen, and a Medical School Dream

AP (Aug. 21, 2014) Contains graphic content. He's only 17. But Johntrell Bowles has wanted to be a doctor from a young age, despite the odds against him. He was recently the youngest participant in a cadaver program at the Indiana University NW medical school. (Aug. 21) Video provided by AP
Powered by NewsLook.com
American Ebola Patients Released: What Cured Them?

American Ebola Patients Released: What Cured Them?

Newsy (Aug. 21, 2014) It's unclear whether the American Ebola patients' recoveries can be attributed to an experimental drug or early detection and good medical care. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins