Featured Research

from universities, journals, and other organizations

Estrogen May Play Role In Prevention Of Cataracts

Date:
October 11, 1999
Source:
Indiana University
Summary:
Indiana University School of Medicine researchers have shown that optic lens cells may be added to the growing list of parts of the body found to be sensitive to the hormone estrogen.

INDIANAPOLIS -- Indiana University School of Medicine researchers have shown that optic lens cells may be added to the growing list of parts of the body found to be sensitive to the hormone estrogen.

Related Articles


Lens cells have receptors for estrogen, adding further evidence to epidemiological research showing that estrogen may play a role in preventing cataracts in aging women. The new work was published in the August 3 issue of Proceedings of the National Academy of Science. Robert M. Bigsby, Ph.D., associate professor of obstetrics and gynecology is the lead author.

In the study, researchers removed the ovaries of rats before treating them with methylnitrosourea, a carcinogenic compound that causes breast cancer in laboratory animals.

The rats were divided into groups that received no estrogen, estradiol (the predominant natural estrogen in pre-menopausal women) or estrone (the predominant natural estrogen in post-menopausal women).

Within six to eight months, 74 percent of the rats receiving no estrogen developed a type of cataract similar to age-related cataracts seen in humans. Only 12 percent of the rats treated with estradiol and 25 percent of those treated with estrone developed cataracts.

"This experimental model gives credence to the epidemiological studies that estrogens are protective against cataracts," said Dr. Bigsby.

Seventy-five percent of people over the age of 75 exhibit some degree of cataracts. It is estimated that more than 50 percent of cases of blindness are caused by cataracts. Age-related cataracts affect more women than men, and one study of women with early onset of menopause showed a 2.9-fold risk of developing cataracts.

"We now have an animal model system that will allow us to determine if the different types of estrogens used in post-menopausal hormone replacement therapy will also prove protective against cataracts," Dr. Bigsby said.


Story Source:

The above story is based on materials provided by Indiana University. Note: Materials may be edited for content and length.


Cite This Page:

Indiana University. "Estrogen May Play Role In Prevention Of Cataracts." ScienceDaily. ScienceDaily, 11 October 1999. <www.sciencedaily.com/releases/1999/10/991011081856.htm>.
Indiana University. (1999, October 11). Estrogen May Play Role In Prevention Of Cataracts. ScienceDaily. Retrieved November 24, 2014 from www.sciencedaily.com/releases/1999/10/991011081856.htm
Indiana University. "Estrogen May Play Role In Prevention Of Cataracts." ScienceDaily. www.sciencedaily.com/releases/1999/10/991011081856.htm (accessed November 24, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Monday, November 24, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

Ebola-Hit Sierra Leone's Late Cocoa Leaves Bitter Taste

AFP (Nov. 23, 2014) The arable district of Kenema in Sierra Leone -- at the centre of the Ebola outbreak in May -- has been under quarantine for three months as the cocoa harvest comes in. Duration: 01:32 Video provided by AFP
Powered by NewsLook.com
Don't Fall For Flu Shot Myths

Don't Fall For Flu Shot Myths

Newsy (Nov. 23, 2014) Misconceptions abound when it comes to your annual flu shot. Medical experts say most people older than 6 months should get the shot. Video provided by Newsy
Powered by NewsLook.com
WFP: Ebola Risks Heightened Among Women Throughout Africa

WFP: Ebola Risks Heightened Among Women Throughout Africa

AFP (Nov. 21, 2014) Having children has always been a frightening prospect in Sierra Leone, the world's most dangerous place to give birth, but Ebola has presented an alarming new threat for expectant mothers. Duration: 00:37 Video provided by AFP
Powered by NewsLook.com
Could Your Genes Be The Reason You're Single?

Could Your Genes Be The Reason You're Single?

Newsy (Nov. 21, 2014) Researchers in Beijing discovered a gene called 5-HTA1, and carriers are reportedly 20 percent more likely to be single. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins