Featured Research

from universities, journals, and other organizations

Novel Prostate Cancer Vaccine Study Under Way At Indiana University School Of Medicine

Date:
June 8, 2000
Source:
Indiana University
Summary:
Indiana University Cancer Center is investigating a new vaccine for treating prostate cancer that has spread beyond the prostate gland.

INDIANAPOLIS -- Indiana University Cancer Center is investigating a new vaccine for treating prostate cancer that has spread beyond the prostate gland.

Vaccination against disease is not a new concept, but in the arena of cancer therapies it is viewed as a possible way to kill malignant cells without damaging healthy cells. In this case, the therapy holds promise because it provides an avenue for treating the malignant cells before they become symptomatic.

Participants in the trial are men who have already undergone surgery or radiation therapy for prostate cancer. Subsequent blood tests for prostate specific antigen indicated their cancer has spread. PSA is produced by the prostate, but patients enrolling in this trial have had their prostates removed or treated with radiation so their PSA levels should be very low or undetectable. Participants in the trial must have no symptoms or findings of disease recurrence other than the elevated PSA.

"Because of the PSA blood test, recurrence of prostate cancer can be detected at an earlier stage than it could be previously," said Christopher Sweeney, M.D., an oncologist at the IU School of Medicine and one of the physicians treating trial participants. "It is hoped the vaccine will boost the patient's immune system and eliminate the cancer while it is still at a low level in the body."

Two vaccines are being tested to determine which treatment regimen is most effective. One uses the vaccinia virus, a relatively harmless virus used in smallpox vaccines, and the second uses the fowlpox vaccine. Both are genetically altered viruses that have been changed to express human PSA. The PSA-bearing virus is attacked by the human immune system and, ideally, the body simultaneously will attack the PSA tumor cells.

Patients are treated with four injections six weeks apart and then followed for at least six months to determine if the PSA tumor cells were eradicated. The IU Cancer Center is one of five sites nationwide enrolling patients for the Phase II trial. The trial is sponsored by the Eastern Cooperative Oncology Group, a national cancer clinical trial cooperative group funded by the National Cancer Institute.

###

People seeking additional information or who want to enroll in the trial may call Karen Fife at 317-274-2552.


Story Source:

The above story is based on materials provided by Indiana University. Note: Materials may be edited for content and length.


Cite This Page:

Indiana University. "Novel Prostate Cancer Vaccine Study Under Way At Indiana University School Of Medicine." ScienceDaily. ScienceDaily, 8 June 2000. <www.sciencedaily.com/releases/2000/06/000608072243.htm>.
Indiana University. (2000, June 8). Novel Prostate Cancer Vaccine Study Under Way At Indiana University School Of Medicine. ScienceDaily. Retrieved July 29, 2014 from www.sciencedaily.com/releases/2000/06/000608072243.htm
Indiana University. "Novel Prostate Cancer Vaccine Study Under Way At Indiana University School Of Medicine." ScienceDaily. www.sciencedaily.com/releases/2000/06/000608072243.htm (accessed July 29, 2014).

Share This




More Health & Medicine News

Tuesday, July 29, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Deadly Ebola Virus Threatens West Africa

Deadly Ebola Virus Threatens West Africa

AP (July 28, 2014) West African nations and international health organizations are working to contain the largest Ebola outbreak in history. It's one of the deadliest diseases known to man, but the CDC says it's unlikely to spread in the U.S. (July 28) Video provided by AP
Powered by NewsLook.com
$15B Deal on Vets' Health Care Reached

$15B Deal on Vets' Health Care Reached

AP (July 28, 2014) A bipartisan deal to improve veterans health care would authorize at least $15 billion in emergency spending to fix a veterans program scandalized by long patient wait times and falsified records. (July 28) Video provided by AP
Powered by NewsLook.com
Two Americans Contract Ebola in Liberia

Two Americans Contract Ebola in Liberia

Reuters - US Online Video (July 28, 2014) Two American aid workers in Liberia test positive for Ebola while working to combat the deadliest outbreak of the virus ever. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Traditional African Dishes Teach Healthy Eating

Traditional African Dishes Teach Healthy Eating

AP (July 28, 2014) Classes are being offered nationwide to encourage African Americans to learn about cooking fresh foods based on traditional African cuisine. The program is trying to combat obesity, heart disease and other ailments often linked to diet. (July 28) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:
from the past week

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins