Featured Research

from universities, journals, and other organizations

Novel Prostate Cancer Vaccine Study Under Way At Indiana University School Of Medicine

Date:
June 8, 2000
Source:
Indiana University
Summary:
Indiana University Cancer Center is investigating a new vaccine for treating prostate cancer that has spread beyond the prostate gland.

INDIANAPOLIS -- Indiana University Cancer Center is investigating a new vaccine for treating prostate cancer that has spread beyond the prostate gland.

Related Articles


Vaccination against disease is not a new concept, but in the arena of cancer therapies it is viewed as a possible way to kill malignant cells without damaging healthy cells. In this case, the therapy holds promise because it provides an avenue for treating the malignant cells before they become symptomatic.

Participants in the trial are men who have already undergone surgery or radiation therapy for prostate cancer. Subsequent blood tests for prostate specific antigen indicated their cancer has spread. PSA is produced by the prostate, but patients enrolling in this trial have had their prostates removed or treated with radiation so their PSA levels should be very low or undetectable. Participants in the trial must have no symptoms or findings of disease recurrence other than the elevated PSA.

"Because of the PSA blood test, recurrence of prostate cancer can be detected at an earlier stage than it could be previously," said Christopher Sweeney, M.D., an oncologist at the IU School of Medicine and one of the physicians treating trial participants. "It is hoped the vaccine will boost the patient's immune system and eliminate the cancer while it is still at a low level in the body."

Two vaccines are being tested to determine which treatment regimen is most effective. One uses the vaccinia virus, a relatively harmless virus used in smallpox vaccines, and the second uses the fowlpox vaccine. Both are genetically altered viruses that have been changed to express human PSA. The PSA-bearing virus is attacked by the human immune system and, ideally, the body simultaneously will attack the PSA tumor cells.

Patients are treated with four injections six weeks apart and then followed for at least six months to determine if the PSA tumor cells were eradicated. The IU Cancer Center is one of five sites nationwide enrolling patients for the Phase II trial. The trial is sponsored by the Eastern Cooperative Oncology Group, a national cancer clinical trial cooperative group funded by the National Cancer Institute.

###

People seeking additional information or who want to enroll in the trial may call Karen Fife at 317-274-2552.


Story Source:

The above story is based on materials provided by Indiana University. Note: Materials may be edited for content and length.


Cite This Page:

Indiana University. "Novel Prostate Cancer Vaccine Study Under Way At Indiana University School Of Medicine." ScienceDaily. ScienceDaily, 8 June 2000. <www.sciencedaily.com/releases/2000/06/000608072243.htm>.
Indiana University. (2000, June 8). Novel Prostate Cancer Vaccine Study Under Way At Indiana University School Of Medicine. ScienceDaily. Retrieved November 26, 2014 from www.sciencedaily.com/releases/2000/06/000608072243.htm
Indiana University. "Novel Prostate Cancer Vaccine Study Under Way At Indiana University School Of Medicine." ScienceDaily. www.sciencedaily.com/releases/2000/06/000608072243.htm (accessed November 26, 2014).

Share This


More From ScienceDaily



More Health & Medicine News

Wednesday, November 26, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Pet Dogs to Be Used in Anti-Ageing Trial

Pet Dogs to Be Used in Anti-Ageing Trial

Reuters - Innovations Video Online (Nov. 26, 2014) Researchers in the United States are preparing to discover whether a drug commonly used in human organ transplants can extend the lifespan and health quality of pet dogs. Video provided by Reuters
Powered by NewsLook.com
From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

From Popcorn To Vending Snacks: FDA Ups Calorie Count Rules

Newsy (Nov. 25, 2014) The US FDA is announcing new calorie rules on Tuesday that will require everywhere from theaters to vending machines to include calorie counts. Video provided by Newsy
Powered by NewsLook.com
Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Daily Serving Of Yogurt Could Reduce Risk Of Type 2 Diabetes

Newsy (Nov. 25, 2014) Need another reason to eat yogurt every day? Researchers now say it could reduce a person's risk of developing type 2 diabetes. Video provided by Newsy
Powered by NewsLook.com
Madagascar Working to Contain Plague Outbreak

Madagascar Working to Contain Plague Outbreak

AFP (Nov. 24, 2014) Madagascar said Monday it is trying to contain an outbreak of plague -- similar to the Black Death that swept Medieval Europe -- that has killed 40 people and is spreading to the capital Antananarivo. Duration: 00:42 Video provided by AFP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins