Featured Research

from universities, journals, and other organizations

UT Southwestern Researchers Test New Treatment For Schizophrenia

Date:
August 22, 2000
Source:
University Of Texas Southwestern Medical Center At Dallas
Summary:
UT Southwestern Medical Center at Dallas psychiatry researchers are testing a new way to deliver a schizophrenia drug that may help curtail the problem of patients not taking their medication, which is common in people with schizophrenia.

UT Southwestern Medical Center at Dallas psychiatry researchers are testing a new way to deliver a schizophrenia drug that may help curtail the problem of patients not taking their medication, which is common in people with schizophrenia.

Related Articles


The drug being tested is a widely prescribed atypical anti-psychotic medication that has been reformulated into an injectable, time-released form that lasts for two weeks, said Dr. Matthew J. Byerly, clinical assistant professor of psychiatry and principal Dallas investigator in the national clinical trial, which will involve 415 patients at numerous academic medical centers.

What's new about the drug is that the anti-psychotic agent is trapped in microspheres, which dissolve slowly in the body and release the drug over time. If the treatment proves successful, then physicians would have an alternative to daily oral medications. While there are older, time-released injectable drugs available, they have many side effects and aren't believed to be as effective as the new drug, which has been used successfully in a daily formulation.

"The medication used in the new treatment is the first of the new generation of atypical anti-psychotic drugs that has been formulated for storage and release over an extended time period," Byerly said.

Volunteer patients in the study will take two to three weeks of oral drug therapy while receiving their initial injections until their blood levels of medication reach the desired level. Some study subjects will be given a placebo. All participants will be required to spend one week as an inpatient. UT Southwestern participants will be hospitalized at Zale Lipshy University Hospital.

"This treatment is yet another step toward finding better treatment options for people with schizophrenia," said Dr. Mary Weber, an instructor of psychiatry in UT Southwestern's schizophrenia research program.

The researchers explained that while many patients may appreciate not having to take daily pills, the new treatment may turn out to be especially important for patients who have difficulty remembering to take their medication. Byerly said that if the new treatment proves as effective as they anticipate, "there will finally be a good option for people with schizophrenia who have difficulty taking medication each day but who cannot tolerate the side effects of existing long-acting medications."

The UT Southwestern researchers are working in conjunction with Dallas Metrocare Services, the largest provider of mental health services in the North Texas area, on the study.

For further information about the trial, call Aimee Waerhouse at 214-648-8302.


Story Source:

The above story is based on materials provided by University Of Texas Southwestern Medical Center At Dallas. Note: Materials may be edited for content and length.


Cite This Page:

University Of Texas Southwestern Medical Center At Dallas. "UT Southwestern Researchers Test New Treatment For Schizophrenia." ScienceDaily. ScienceDaily, 22 August 2000. <www.sciencedaily.com/releases/2000/08/000811062353.htm>.
University Of Texas Southwestern Medical Center At Dallas. (2000, August 22). UT Southwestern Researchers Test New Treatment For Schizophrenia. ScienceDaily. Retrieved January 30, 2015 from www.sciencedaily.com/releases/2000/08/000811062353.htm
University Of Texas Southwestern Medical Center At Dallas. "UT Southwestern Researchers Test New Treatment For Schizophrenia." ScienceDaily. www.sciencedaily.com/releases/2000/08/000811062353.htm (accessed January 30, 2015).

Share This


More From ScienceDaily



More Health & Medicine News

Friday, January 30, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC: Get Vaccinated for Measles

CDC: Get Vaccinated for Measles

Reuters - US Online Video (Jan. 30, 2015) The CDC is urging people to get vaccinated for measles amid an outbreak that began at Disneyland and has now infected more than 90 people. Linda So reports. Video provided by Reuters
Powered by NewsLook.com
Obama To Outline New Plan For Personalized Medicine

Obama To Outline New Plan For Personalized Medicine

Newsy (Jan. 30, 2015) President Obama is expected to speak with drugmakers Friday about his Precision Medicine Initiative first introduced last week. Video provided by Newsy
Powered by NewsLook.com
Oxfam Calls for Massive Aid for Ebola-Hit West Africa

Oxfam Calls for Massive Aid for Ebola-Hit West Africa

AFP (Jan. 29, 2015) Oxfam International has called for a multi-million dollar post-Ebola "Marshall Plan", with financial support given by wealthy countries, to help Guinea, Sierra Leone and Liberia to recover. Duration: 01:10 Video provided by AFP
Powered by NewsLook.com
Are We Winning The Fight Against Ebola?

Are We Winning The Fight Against Ebola?

Newsy (Jan. 29, 2015) The World Health Organization announced the fight against Ebola has entered its second phase as the number of cases per week has steadily dropped. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins