Featured Research

from universities, journals, and other organizations

Progress In Auditory Hair Cell Studies In Birds Points Way To Possible Human Hearing Improvement

Date:
October 24, 2000
Source:
University Of Washington
Summary:
Scientists have known for years that birds' ears do something human ears cannot: when hair cells in the avian ear are destroyed, the bird goes deaf only temporarily. Now, research at the University of Washington is showing why.

Scientists have known for years that birds' ears do something human ears cannot: when hair cells in the avian ear are destroyed, the bird goes deaf only temporarily. Now, research at the University of Washington is showing why.

In a paper published in the Oct. 24 issue of the Proceedings of the National Academy of Sciences, Dr. Edwin W. Rubel, the Bloedel professor of hearing science, and Research Assistant Professor Jennifer Stone explain what is known about how the process works in birds. Once that mechanism is completely traced, the next step will be studies of how that knowledge might be transferred to mammals, including humans.

"What we detail in this paper is the sequence of events the cells go through in order to make new hair cells. In most cases, this involves a support cell that sits near the base of a hair cell," Rubel said in a recent interview at the UW Virginia Bloedel Hearing Research Center and Department of Otolaryngology. "When the nearby avian hair cell dies, this support cell is stimulated by some external process to develop into a new hair cell, just like human skin cells."

The new hair cell then somehow gets linked to the brain and the nervous system and develops all the same biochemical characteristics the original hair cell had. This doesn't happen in mammals. Stone said the discovery of this capability in birds at the UW 12 years ago contradicted everything then known about neurobiology and hearing. When hair cells in humans and other warm-blooded vertebrates are killed, the nearby cells do not start dividing as they did before birth.

Rubel said the key is understanding how the mechanism for the destruction of a hair cell could be stopped. If researchers can establish the cascade of steps involved in the cellular death, they would be able to interrupt the process, and prevent the development of some forms of deafness before they start.

Stone and Rubel agreed their research would not lead directly to a cure for human deafness in the near future.

"It's really important to recognize the increased complexity of the mammalian auditory organ, compared to the birds'," Stone said. "Simply making a hair cell, while it seems like an automatic process in a chicken, is a much larger task in a human, because of the complexity of the mammalian auditory system."

The research has opened new paths for significant progress in hearing protection and conservation directly as a result of the avian hair cell research. Rubel and Stone said they hope their work attracts more investigators to the field, in search of more solutions to hearing loss.

"When people ask me if we have cured deafness, I say what we've done is establish the question. We established the possibility that other approaches could be used besides hearing aids and cochlear implants," Rubel said. "These are areas that researchers weren't even considering before. That's how one establishes a new area of research and draws more researchers into it, multiplying the progress dramatically."

Rubel first reported the phenomenon of avian auditory hair cell regeneration in a Science article 12 years ago.


Story Source:

The above story is based on materials provided by University Of Washington. Note: Materials may be edited for content and length.


Cite This Page:

University Of Washington. "Progress In Auditory Hair Cell Studies In Birds Points Way To Possible Human Hearing Improvement." ScienceDaily. ScienceDaily, 24 October 2000. <www.sciencedaily.com/releases/2000/10/001023204257.htm>.
University Of Washington. (2000, October 24). Progress In Auditory Hair Cell Studies In Birds Points Way To Possible Human Hearing Improvement. ScienceDaily. Retrieved October 21, 2014 from www.sciencedaily.com/releases/2000/10/001023204257.htm
University Of Washington. "Progress In Auditory Hair Cell Studies In Birds Points Way To Possible Human Hearing Improvement." ScienceDaily. www.sciencedaily.com/releases/2000/10/001023204257.htm (accessed October 21, 2014).

Share This



More Health & Medicine News

Tuesday, October 21, 2014

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

CDC Revamps Ebola Guidelines After Criticism

CDC Revamps Ebola Guidelines After Criticism

Newsy (Oct. 21, 2014) The Centers for Disease Control and Prevention have issued new protocols for healthcare workers interacting with Ebola patients. Video provided by Newsy
Powered by NewsLook.com
WHO: Ebola Vaccine Trials to Start a in January

WHO: Ebola Vaccine Trials to Start a in January

AP (Oct. 21, 2014) Tens of thousands of doses of experimental Ebola vaccines could be available for "real-world" testing in West Africa as soon as January as long as they are deemed safe in soon to start trials, the World Health Organization said Tuesday. (Oct. 21) Video provided by AP
Powered by NewsLook.com
First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

First-Of-Its-Kind Treatment Gives Man Ability To Walk Again

Newsy (Oct. 21, 2014) A medical team has for the first time given a man the ability to walk again after transplanting cells from his brain onto his severed spinal cord. Video provided by Newsy
Powered by NewsLook.com
CDC Issues New Ebola Guidelines for Health Workers

CDC Issues New Ebola Guidelines for Health Workers

Reuters - US Online Video (Oct. 21, 2014) The U.S. Centers for Disease Control and Prevention has set up new guidelines for health workers taking care of patients infected with Ebola. Linda So reports. Video provided by Reuters
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins