Featured Research

from universities, journals, and other organizations

Study Reports Increase Of Brain Tumors In New York; Possible Clues To Origin Of The Most Common Type

Date:
January 4, 2001
Source:
Roswell Park Cancer Institute
Summary:
The "not so good news" from a recent study conducted at Roswell Park Cancer Institute (RPCI) is that the incidence rates for two forms of common brain tumors - glioblastoma multiforme (GBM) and anaplastic astrocytoma (AA) - have increased in New York State between 1976 and 1995. The "good news" is that the study may have revealed clues to the origins of GBM; the most common of these tumors.

BUFFALO, NY - The "not so good news" from a recent study conducted at Roswell Park Cancer Institute (RPCI) is that the incidence rates for two forms of common brain tumors - glioblastoma multiforme (GBM) and anaplastic astrocytoma (AA) - have increased in New York State between 1976 and 1995. The "good news" is that the study may have revealed clues to the origins of GBM; the most common of these tumors.

Related Articles


The study by Brian P. McKinley, MD, Department of Surgery, and colleagues at RPCI, is published in the December 2000 edition of the Journal of Neurosurgery.

The research team used data from the New York State Cancer Registry (NYSCR) to calculate crude, age- and sex-specific incidence rates for each of the three tumor types from 1976 to 1995. Their review of the NYSCR data identified 11,204 cases of GBM, 4,613 cases of astrocytoma not otherwise specified (ANOS), and 878 cases of AA diagnosed during that time period. The results demonstrated statistically significant increases in the age-adjusted incidence of GBM (33% for men, 55% for women) and AA (150% for men, 160% for women); as well as an apparent increase of ANOS (75% for men, 50% for women) which was not statistically significant.

"Our analysis of GBM, ANOS and AA cases confirms that as a group, the incidence of these central nervous system malignancies has increased over the last two decades in New York State," according to Dr. McKinley. The authors are quick to point out that their data cannot fully explain the increased incidence observed in each of these tumors.

"We believe that the dominant reasons for these increases are improved diagnostic methods and a more aggressive diagnostic approach toward the elderly," notes McKinley. "But, we are not willing to rule out changes in environmental exposures, tumorigenesis, or an inherent susceptibility of elderly as being responsible for these observations."

Interestingly, while the incidence of GBM increased in both men and women during the study period, men have an overall incidence of GBM that is one and a half to two times that of women. "This trend toward lower risk of GBM in the female population appears to begin around the age of menarche and to be mitigated by menopause," according to McKinley. The authors report that while other studies have inferred an overall protective effect of female gender on GBM and laboratory studies have also supported the potential role of female sex hormones, their data are the first to demonstrate this effect in a large, population-based study of GBM incidence.

"The combination of these studies and data from our large population-based analysis of GBM incidence should provide the impetus to investigate the potential roles that sex hormones and their metabolites may have in the origins of GBM," the authors conclude. "An analysis of these factors as well as the contributions of genetic differences between the sexes in the pathology and epidemiology of GBM should be pursued aggressively."

Roswell Park Cancer Institute was founded in 1898, is the nation's first cancer research, treatment and education center and is the only National Cancer Institute-designated comprehensive cancer center in Western New York.


Story Source:

The above story is based on materials provided by Roswell Park Cancer Institute. Note: Materials may be edited for content and length.


Cite This Page:

Roswell Park Cancer Institute. "Study Reports Increase Of Brain Tumors In New York; Possible Clues To Origin Of The Most Common Type." ScienceDaily. ScienceDaily, 4 January 2001. <www.sciencedaily.com/releases/2001/01/010102061602.htm>.
Roswell Park Cancer Institute. (2001, January 4). Study Reports Increase Of Brain Tumors In New York; Possible Clues To Origin Of The Most Common Type. ScienceDaily. Retrieved January 25, 2015 from www.sciencedaily.com/releases/2001/01/010102061602.htm
Roswell Park Cancer Institute. "Study Reports Increase Of Brain Tumors In New York; Possible Clues To Origin Of The Most Common Type." ScienceDaily. www.sciencedaily.com/releases/2001/01/010102061602.htm (accessed January 25, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Sunday, January 25, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

How Technology Is Ruining Snow Days For Students

How Technology Is Ruining Snow Days For Students

Newsy (Jan. 25, 2015) — More schools are using online classes to keep from losing time to snow days, but it only works if students have Internet access at home. Video provided by Newsy
Powered by NewsLook.com
Smart Wristband to Shock Away Bad Habits

Smart Wristband to Shock Away Bad Habits

Reuters - Innovations Video Online (Jan. 23, 2015) — A Boston start-up is developing a wristband they say will help users break bad habits by jolting them with an electric shock. Ben Gruber reports. Video provided by Reuters
Powered by NewsLook.com
Amazing Technology Allows Blind Mother to See Her Newborn Son

Amazing Technology Allows Blind Mother to See Her Newborn Son

RightThisMinute (Jan. 23, 2015) — Not only is Kathy seeing her newborn son for the first time, but this is actually the first time she has ever seen a baby. Kathy and her sister, Yvonne, have been legally blind since childhood, but thanks to an amazing new technology, eSight glasses, which gives those who are legally blind the ability to see, she got the chance to see the birth of her son. It&apos;s an incredible moment and an even better story. Video provided by RightThisMinute
Powered by NewsLook.com
One Dose, Then Surgery to Test Tumor Drugs Fast

One Dose, Then Surgery to Test Tumor Drugs Fast

AP (Jan. 23, 2015) — A Phoenix hospital is experimenting with a faster way to test much needed medications for deadly brain tumors. Patients get a single dose of a potential drug, and hours later have their tumor removed to see if the drug had any affect. (Jan. 23) Video provided by AP
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
 
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:  

Breaking News:

Strange & Offbeat Stories

 

Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:  

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile iPhone Android Web
Follow Facebook Twitter Google+
Subscribe RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins