Featured Research

from universities, journals, and other organizations

Smoking Cigarettes, Cigars, Pipes Or Using Snuff Or Chewing Tobacco Does Not Cause Brain Cancer, Yale Study Shows

Date:
May 15, 2001
Source:
Yale University
Summary:
Although cigarette smoking and use of other tobacco products are considered to be the greatest single source of human exposure to certain carcinogens, they do not appear to cause brain cancer, a Yale investigation has found.

New Haven, Conn. – Although cigarette smoking and use of other tobacco products are considered to be the greatest single source of human exposure to certain carcinogens, they do not appear to cause brain cancer, a Yale investigation has found.

Related Articles


"Brain cancer incidence and mortality have been increasing in many industrialized countries," said Tongzhang Zheng, associate professor of epidemiology and environmental health at Yale School of Medicine and principal investigator of the study published in a recent issue of the journal Cancer Epidemiology, Biomarkers & Prevention. "Some have suggested that cigarette smoking and other tobacco product use may increase the risk of brain tumors because tobacco product use is considered to be the greatest source for human exposure to N-nitroso compounds, which are potent nervous system carcinogens in animal studies. Our investigation, however, did not find a positive association between cigarette smoking, or with use of other tobacco products, and risk of brain cancer."

Zheng said some studies have shown persons who smoked non-filtered cigarettes were at higher risk for brain cancer, but his investigation did not find an association. In addition, "there was no increased risk of brain cancer by various smoking characteristics, including age started smoking, years of smoking, number of cigarettes per day or life-time pack-years of smoking," he said.

The study, based on data from the state of Iowa, included 375 confirmed cases of glioma, and 2,434 population-based controls.

The aging, curing, fermentation and processing of tobacco and nicotine can give rise to carcinogenic N-nitroso compounds in tobacco products. Laboratory tests have shown ingestion of tobacco products causes brain tumors in mice.

"This is one of only a few studies to systematically examine the risk of a specific histological type of brain cancer, glioma, with use of particular types of tobacco products, including cigarettes, cigars or pipes, snuff and chewing tobacco, among both males and females," Zheng said. "Most of the earlier studies only compared smokers with those who never smoked, and lacked information on age smoking began, type of tobacco products used, duration or intensity of smoking. Very few studies have also reported the findings related to use of other tobacco products."

He said he did not know why ingestion of tobacco products would cause brain cancer in mice but not humans, but speculated that the human brain-blood barrier may limit the actual amount of N-nitroso compounds that reach the brain tissue.

Co-authors of the published findings were Kenneth Cantor of the National Cancer Institute; Yawei Zhang of the Department of Epidemiology and Public Health at Yale; Brian Chiu of the Department of Preventive and Societal Medicine at the University of Nebraska Medical Center, and Charles Lynch of the Department of Epidemiology at the University of Iowa College of Public Health.


Story Source:

The above story is based on materials provided by Yale University. Note: Materials may be edited for content and length.


Cite This Page:

Yale University. "Smoking Cigarettes, Cigars, Pipes Or Using Snuff Or Chewing Tobacco Does Not Cause Brain Cancer, Yale Study Shows." ScienceDaily. ScienceDaily, 15 May 2001. <www.sciencedaily.com/releases/2001/05/010510072748.htm>.
Yale University. (2001, May 15). Smoking Cigarettes, Cigars, Pipes Or Using Snuff Or Chewing Tobacco Does Not Cause Brain Cancer, Yale Study Shows. ScienceDaily. Retrieved April 24, 2015 from www.sciencedaily.com/releases/2001/05/010510072748.htm
Yale University. "Smoking Cigarettes, Cigars, Pipes Or Using Snuff Or Chewing Tobacco Does Not Cause Brain Cancer, Yale Study Shows." ScienceDaily. www.sciencedaily.com/releases/2001/05/010510072748.htm (accessed April 24, 2015).

Share This


More From ScienceDaily



More Mind & Brain News

Friday, April 24, 2015

Featured Research

from universities, journals, and other organizations


Featured Videos

from AP, Reuters, AFP, and other news services

Judge OKs 65-Year Deal Over NFL Concussions

Judge OKs 65-Year Deal Over NFL Concussions

AP (Apr. 23, 2015) A judge has approved a potential $1 billion plan to resolve thousands of NFL concussion lawsuits filed by retired players. The NFL expects 6,000 of nearly 20,000 retired players to suffer from Alzheimer&apos;s disease or moderate dementia someday.(April 23) Video provided by AP
Powered by NewsLook.com
Research Says Complex Tools Might Not Be 'Our Thing' Anymore

Research Says Complex Tools Might Not Be 'Our Thing' Anymore

Newsy (Apr. 21, 2015) The use of complex tools has often been seen as a defining characteristic of humanity, but that notion is now in question. Video provided by Newsy
Powered by NewsLook.com
Our Love Of Puppy Dog Eyes Explained By Science

Our Love Of Puppy Dog Eyes Explained By Science

Newsy (Apr. 17, 2015) Researchers found a spike in oxytocin occurs in both humans and dogs when they gaze into each other&apos;s eyes. Video provided by Newsy
Powered by NewsLook.com
Scientists Find Link Between Gestational Diabetes And Autism

Scientists Find Link Between Gestational Diabetes And Autism

Newsy (Apr. 17, 2015) Researchers who analyzed data from over 300,000 kids and their mothers say they&apos;ve found a link between gestational diabetes and autism. Video provided by Newsy
Powered by NewsLook.com

Search ScienceDaily

Number of stories in archives: 140,361

Find with keyword(s):
Enter a keyword or phrase to search ScienceDaily for related topics and research stories.

Save/Print:
Share:

Breaking News:

Strange & Offbeat Stories


Health & Medicine

Mind & Brain

Living & Well

In Other News

... from NewsDaily.com

Science News

Health News

Environment News

Technology News



Save/Print:
Share:

Free Subscriptions


Get the latest science news with ScienceDaily's free email newsletters, updated daily and weekly. Or view hourly updated newsfeeds in your RSS reader:

Get Social & Mobile


Keep up to date with the latest news from ScienceDaily via social networks and mobile apps:

Have Feedback?


Tell us what you think of ScienceDaily -- we welcome both positive and negative comments. Have any problems using the site? Questions?
Mobile: iPhone Android Web
Follow: Facebook Twitter Google+
Subscribe: RSS Feeds Email Newsletters
Latest Headlines Health & Medicine Mind & Brain Space & Time Matter & Energy Computers & Math Plants & Animals Earth & Climate Fossils & Ruins